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The map label for this gene is lpfB [H]

Identifier: 209398252

GI number: 209398252

Start: 4559865

End: 4560554

Strand: Reverse

Name: lpfB [H]

Synonym: ECH74115_4921

Alternate gene names: 209398252

Gene position: 4560554-4559865 (Counterclockwise)

Preceding gene: 209397169

Following gene: 209397444

Centisome position: 81.85

GC content: 42.61

Gene sequence:

>690_bases
ATGATGAAAAGTAAATTTGTTGCGTTGGCTCTCTCTCTGTTCCTTTCACAGTCAGTTCTGGCGGGTGGCGTCGGACTTAG
CTCTACTCGCGTAATTTATGATGGCAGTAAGAAAGAAGCCTCGCTGACCGTACAGAATAAAAGTAAGACGGAAGAGTTTC
TTATCCAATCCTGGGTGGATGATGCCGCGGGCAGCAAAAAAACACCGTTTATTATTACGCCCCCACTATTCAAGCTTGAT
CCAGAAAAGAACAATATTTTGCGTATTGTGAATATTACGCCCGGCCTGCCTCAGGATCGCGAATCGGTCTACTGGGTTAA
TGTGAAAGCCATTCCATCTAAAAGTGACGACAGCGAAAACAAAAATGTTTTGCAGATTGCCGTTCGCACCCGAATCAAAC
TTTTTTATCGCCCGGCAGGTTTAAAGGGTGATGTAAAAACCGCGCCAAATGAACTGCGATTTACGCGTAACGGTAATCAG
CTCCGCGTTGATAATCCGACAGTTTTTAATATTACCTTTAATCAATTTTTTGCGAATGACAAAGAAATTGAAAAAGCAGG
CATGGTACCCGCTAAAGGGGCATTAAATATCACATTACCCGCCGGGGTAGGTAGCGTTTCTAAAATTAAATATAACACCA
TCAATGACTTTGGATCGTCAGCGGAAATGATCACTAAAAATGTTGATTGA

Upstream 100 bases:

>100_bases
GGCAATGCGCAGGTCGATTTCAACCTGTCTTACGAGTAATCGTCCGTTTTACAAATGGCGGCGTAATTGCCGCCATTAGT
CGTCAAAGTTCATGGATCGA

Downstream 100 bases:

>100_bases
TTAATATCTTTTCAGGAGAAATAGCTCAATGTCACGGAAGACCGTTTCACGTACTTTTTCTTCCTTTTCTATCTCTGTGG
TGGCGGTTGCTGTTGCCAGC

Product: chaperone protein FimC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVDDAAGSKKTPFIITPPLFKLD
PEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSENKNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQ
LRVDNPTVFNITFNQFFANDKEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD

Sequences:

>Translated_229_residues
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVDDAAGSKKTPFIITPPLFKLD
PEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSENKNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQ
LRVDNPTVFNITFNQFFANDKEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD
>Mature_229_residues
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVDDAAGSKKTPFIITPPLFKLD
PEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSENKNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQ
LRVDNPTVFNITFNQFFANDKEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD

Specific function: Required for the biogenesis of long polar fimbria; binds and interact with lpfA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=219, Percent_Identity=43.8356164383562, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789532, Length=230, Percent_Identity=40.4347826086956, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1786743, Length=222, Percent_Identity=40.0900900900901, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1787171, Length=214, Percent_Identity=38.3177570093458, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786333, Length=238, Percent_Identity=33.1932773109244, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786936, Length=207, Percent_Identity=30.9178743961353, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788677, Length=196, Percent_Identity=34.1836734693878, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788428, Length=180, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082203, Length=224, Percent_Identity=29.4642857142857, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87081806, Length=230, Percent_Identity=30.8695652173913, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 25198; Mature: 25198

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHH
DAAGSKKTPFIITPPLFKLDPEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSEN
HHCCCCCCCEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCC
KNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQLRVDNPTVFNITFNQFFAND
CCEEEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEHHHHHCCC
KEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD
HHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHEEECCC
>Mature Secondary Structure
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVD
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHH
DAAGSKKTPFIITPPLFKLDPEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSEN
HHCCCCCCCEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCCCC
KNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQLRVDNPTVFNITFNQFFAND
CCEEEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEECCCEEEEEEHHHHHCCC
KEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD
HHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721701; 11677609 [H]