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The map label for this gene is lpfD [H]

Identifier: 209397444

GI number: 209397444

Start: 4556193

End: 4557248

Strand: Reverse

Name: lpfD [H]

Synonym: ECH74115_4918

Alternate gene names: 209397444

Gene position: 4557248-4556193 (Counterclockwise)

Preceding gene: 209398252

Following gene: 209398023

Centisome position: 81.79

GC content: 47.63

Gene sequence:

>1056_bases
ATGAAAGCGGCAATAGCATTATCCTTATTAGGATGCGTATTCGGATTTTCTGGCAAGGCATTTGCCGGAGATGCGTGGGG
GCCATGTACCCCCGCGGATGGCACGACTTATCACTATAATGTCGATGTGGATGTTGGTATACCTGATGCGGCAAAAAACG
TCGCAGGAACGGTTTTACCGGATGTCCTTAACTGGTCTAATGGACAAAACGTATCGCTAATTTGTGAATGTCCTGATTCT
TATAAGAATGAAAAAGATACTCTAGTGCAGGGGGTGAGTATGCTTCCCCCTTCTGGCCGTACGGTTGACAGTATGAAATA
TTATACTTTGACGGAGGAACTGGAGGTTGCGACGAACATTCGCATCAGTACCAGTGTGTATGGGTTTGTTCCTTTCAAAA
ACCAGCAGGCGCTGCAAACAACCGGATGCAACAAAGTCATTACTACGCCCTATATGGGCGGCGCAGGTCTACTTTCCTTT
GCTATTACTAAACCCTTTATCGGCGATTCCGTCATCCCTCTGACGTTAATTGCCGAACTGTATGCCTCGAAAACAAATAA
AGATTACGGAACAATACCCATATCTTCCGTATCTATTCAGGGGCGTGTCACCGTAACCCAGGATTGCGAAATTAAACCCG
GCACGGTGCTGGATGTGCCATTTGGTGAATTCCCCTCCTCGGCGTTTAAAAACAGGCAAGGGCAAATGCCTGAAGGTGCG
ACAGAGCAAGAAATTAACCTCAGCTTCGATTGCAACAATATCTCTGATGGTATCAAGGTTGCGTTGCGCCTTGAGGGGGC
AACCAATGCTGACGATCCCCGAGCGGTGGATATGGGCAACCCCGATATTGGCGTACTGGTGAAAGATTCCAGCGGCAAAA
TTTTGGTACCGAATGATTCAAGCAGCACCACGTTATTAAATTTGAGCAGCCTGGATTCTAAAACTCACCGCAATGCCGCG
ATTCGACTGCTGGCTTTACCGATTAGCACGACGGGTAAAGCGCCTAAAGGCGGGACGTTTGAAGGCGTAACGACCATATA
TCTTGAAATGGAGTGA

Upstream 100 bases:

>100_bases
CGTCGCAGCAATGCGTGGCGCCTTATAAATTATCCCTGGAATTAAAACAGGGCGGAATTATTCCTGTTTCGGCCAATTGC
CAGTAAGCAAGGAGAGCGAA

Downstream 100 bases:

>100_bases
TGCCATGAAGTTCAAACGATTGCTGCATAGCGGCATCGCCAGTTTGAGTCTGGTTGCCTGCGGGGTGAATGCGGCGACGG
ATCTTGGCCCGGCAGGGGAT

Product: protein LpfD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLPDVLNWSNGQNVSLICECPDS
YKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNIRISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSF
AITKPFIGDSVIPLTLIAELYASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDSSSTTLLNLSSLDSKTHRNAA
IRLLALPISTTGKAPKGGTFEGVTTIYLEME

Sequences:

>Translated_351_residues
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLPDVLNWSNGQNVSLICECPDS
YKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNIRISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSF
AITKPFIGDSVIPLTLIAELYASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDSSSTTLLNLSSLDSKTHRNAA
IRLLALPISTTGKAPKGGTFEGVTTIYLEME
>Mature_351_residues
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLPDVLNWSNGQNVSLICECPDS
YKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNIRISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSF
AITKPFIGDSVIPLTLIAELYASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDSSSTTLLNLSSLDSKTHRNAA
IRLLALPISTTGKAPKGGTFEGVTTIYLEME

Specific function: Involved In Regulation Of Length And Mediation Of Adhesion Of Sfma Fimbriae (But Not Necessary For The Production Of Fimbriae). Seems To Be Mannose Binding Adhesin (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI145693100, Length=256, Percent_Identity=27.34375, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787173, Length=340, Percent_Identity=25, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789534, Length=274, Percent_Identity=25.5474452554745, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37240; Mature: 37240

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLP
CCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHCCHHHH
DVLNWSNGQNVSLICECPDSYKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNI
HHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEHEEEE
RISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSFAITKPFIGDSVIPLTLIAEL
EEEEEEEEEEECCCCCHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHH
YASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
HHHCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCC
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDS
CCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCEEEEECCC
SSTTLLNLSSLDSKTHRNAAIRLLALPISTTGKAPKGGTFEGVTTIYLEME
CCEEEEEEHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLP
CCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHCCHHHH
DVLNWSNGQNVSLICECPDSYKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNI
HHHCCCCCCCEEEEEECCHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCEEHEEEE
RISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSFAITKPFIGDSVIPLTLIAEL
EEEEEEEEEEECCCCCHHHHCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHH
YASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
HHHCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCCC
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDS
CCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCEEEEECCC
SSTTLLNLSSLDSKTHRNAAIRLLALPISTTGKAPKGGTFEGVTTIYLEME
CCEEEEEEHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721701; 11677609 [H]