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The map label for this gene is ygcN [H]

Identifier: 209397050

GI number: 209397050

Start: 3717172

End: 3718443

Strand: Direct

Name: ygcN [H]

Synonym: ECH74115_4021

Alternate gene names: 209397050

Gene position: 3717172-3718443 (Clockwise)

Preceding gene: 209396419

Following gene: 209398115

Centisome position: 66.71

GC content: 54.72

Gene sequence:

>1272_bases
ATGGAAGACGACTGCGACATTATTATTATTGGTGCCGGTATTGCAGGCACCGCTTGCGCGTTACGCTGCGCGCGAGCGGG
TTTATCCGTTTTGTTACTGGAACGCGCTGAAATCCCCGGCAGCAAAAATCTTTCCGGCGGGCGGTTATATACCCATGCAC
TCGCGGAACTCCTCCCTCAATTTCATCTGACCGCGCCTCTTGAACGACGCATCACTCACGAAAGCCTTTCCCTGTTAACG
CCGGATTGCGCAACGACGTTTTCCAGCTTACAGCCCGGCGGTGAATCCTGGAGTGTATTACGTGCACGGTTCGATCCGTG
GCTGGTTGCCGAAGCCGAAAAAGAAGGTGTCGAATGCATCCCTGGTGCGACGGTGGATGCACTGTATGAAGAAAACGGCA
GGGTGTGTGGTGTCATTTGTGGTGACGATATTCTCCGCGCCCGTTATGTGGTGCTGGCAGAAGGTGCCAACAGCGTCCTG
GCTGAACGTCACGGGTTAGTGACTCGTCCTGCTGGCGAAGCGATGGCGTTGGGGATCAAAGAAGTGCTGTCGCTGGAAAC
ATCCGCTATTGAAGAACGTTTTCATCTGGAGAATAACGAAGGCGCAGCGTTGCTGTTCAGCGGCGGAATCTGTGATGACT
TACCCGGCGGCGCATTTCTTTATACTAATCAACAAACGCTCTCGTTAGGGATTGTTTGCCCACTCTCTTCCCTTACGCAA
AGTCGTGTTCCGGCAAGCGAGCTGCTTGCTCGCTTTAAAACGCATCCGGCAGTGCGCCCGCTTATCAAAAACACGGAATC
ACTGGAGTATGGTGCGCATCTGGTGCCAGAAGGTGGCTTGCACAGTATGCCGGTACAATACGCCGGTAACGGCTGGCTGC
TGGTGGGCGATGCGTTGCGCAGTTGCGTCAATACCGGAATTTCTGTGCGCGGCATGGATACGGCGCTAACTGGCGCGCAG
GCGGCGGCACAAACACTGATAAGCGCCTGCCAGCACCGCGAGCCGCAAAATCTGTTTCCGCTTTATCATCACAACGTAGA
GCGCAGCCTGCTGTGGGATGTTCTACAGCGTTATCAGCATGTTCCGGTGCTTTTGCAACGCCCGGGATGGTACCGTACGT
GGCCTGCGTTAATGCAGGATATTTCCCGCGATTTATGGGATCAGGGTGATAAACCTGTTCCACCGCTGCGCCAGTTACTC
TGGCGTCATTTACGTCGTCATGGCTTGTGGAATCTGGCGGGCGATGTTATCAGGAGTGTTCGATGTCTGTAG

Upstream 100 bases:

>100_bases
GTTGTATCTATCGCGGCGAATGATAAGAGTGTGGCGGCGGTCAATTTCCCTTAAGTAACGCTATGTTAGGGTGTTGTGTT
CAGGATATCTGGGGCATGAC

Downstream 100 bases:

>100_bases
CCCGTAATCTCTGGCGCGCTGCTGATGCGCCGCACATTGTTCCGGCTGACTCCGTTGAGCGTCAGATGGTACAACGGTTG
ATTAACGCCTGTCCGGTAGG

Product: pyridine nucleotide-disulphide oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLL
WRHLRRHGLWNLAGDVIRSVRCL

Sequences:

>Translated_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLL
WRHLRRHGLWNLAGDVIRSVRCL
>Mature_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLL
WRHLRRHGLWNLAGDVIRSVRCL

Specific function: Probably accepts electrons from ygcQ/ygcR and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=400, Percent_Identity=25, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI87082155, Length=423, Percent_Identity=97.3995271867612, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=428, Percent_Identity=42.2897196261682, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=41.1214953271028, Blast_Score=332, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI25144720, Length=397, Percent_Identity=25.9445843828715, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324932, Length=367, Percent_Identity=26.9754768392371, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24652256, Length=407, Percent_Identity=25.7985257985258, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 46259; Mature: 46259

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDTALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCC
VPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWNLAGDVIRSV
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RCL
CCC
>Mature Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDTALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHCC
VPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLLWRHLRRHGLWNLAGDVIRSV
CCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
RCL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]