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The map label for this gene is hypD [H]

Identifier: 209396571

GI number: 209396571

Start: 3680265

End: 3681386

Strand: Direct

Name: hypD [H]

Synonym: ECH74115_3981

Alternate gene names: 209396571

Gene position: 3680265-3681386 (Clockwise)

Preceding gene: 209398163

Following gene: 209396976

Centisome position: 66.05

GC content: 55.97

Gene sequence:

>1122_bases
ATGCGTTTTGTTGATGAATATCGCGCGCCGGAACAGGTGATGCAGTTAATTGAGCATCTGCGCGAACGTGCTTCACATCT
CTCTTACACCGCCGAACGCCCTCTGCGGATTATGGAAGTGTGCGGTGGTCATACCCACGCCATTTTTAAATTCGGCCTCG
ACCAGTTACTGCCTGAAAACGTTGAGTTTATCCACGGTCCGGGTTGCCCGGTGTGCGTACTGCCGATGGGCAGAATCGAC
ACCTGCGTGGAGATTGCCAGCCATCCGGAAGTCATCTTCTGTACCTTTGGCGACGCCATGCGCGTGCCGGGGAAACAGGG
ATCGCTGTTGCAGGCAAAAGCACGCGGTGCCGATGTGCGCATCGTCTATTCGCCGATGGATGCGTTGAAACTGGCGCAGG
AGAATCCAACCCGCAAAGTGGTGTTCTTCGGCTTAGGTTTTGAAACCACCATGCCGACCACCGCCATCACTCTGCAACAG
GCGAAAGCGCGTGATGTGCAGAATTTTTACTTCTTCTGCCAGCATATTACGCTTATCCCGACGCTGCGCAGTTTGCTGGA
ACAGCCGGATAACGGTATCGACGCGTTCCTCGCGCCGGGCCACGTTAGTATGGTTATCGGCACTGATGCCTATAATTTTA
TCGCCAGCGATTTTCAGCGTCCGCTGGTGGTGGCTGGTTTCGAACCCCTTGATCTACTGCAAGGCGTGGTCATGCTGGTG
GAGCAGAAAATAGCGGCCCACAGCAAGGTAGAGAATCAGTATCGTCGGGTGGTACCGGATGCCGGTAACCTGCTGGCGCA
ACAGGCGATTGCCGATGTGTTCTGTGTCAACGGCGACAGCGAATGGCGCGGCTTAGGCGTGATTGAATCTTCTGGCGTGC
ACCTGACGCCGGATTATCAACGATTCGATGCCGAAGCACATTTCCGCCCGGCACCGCAGCAGGTCTGCGATGACCCGCGC
GCGCGTTGTGGCGAAGTCTTGACGGGCAAATGTAAGCCGCATCAATGCCCGCTGTTTGGTAACACCTGTAATCCTCAAAC
CGCGTTTGGTGCGCTGATGGTTTCCTCCGAAGGAGCGTGCGCCGCGTGGTATCAGTATCGTCAGCAGGAGAGTGAAGCGT
GA

Upstream 100 bases:

>100_bases
TAATTAATGAAGCCGAAGCACGCGACACTCTCGACGCCTTGCAAAACATGTTTGACGTTGAGCCGGATGTCGGCGCGCTG
TTGTATGGCGAGGAAAAATA

Downstream 100 bases:

>100_bases
ATAATATCCAACTCGCCCACGGTAGCGGCGGCCAGGCGATGCAGCAATTAATCAACAGCCTGTTTATGGAAGCCTTTGCC
AACCCGTGGCTGGCAGAGCA

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
TCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPR
ARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA

Sequences:

>Translated_373_residues
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
TCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPR
ARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA
>Mature_373_residues
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
TCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPR
ARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=373, Percent_Identity=99.4638069705094, Blast_Score=773, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41356; Mature: 41356

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVR
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEHHCCCCCEE
IVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQAKARDVQNFYFFCQHITLIP
EEECCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHH
TLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
HHHHHHHCCCCCCCEEECCCEEEEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCEEECCCHH
RFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGAC
HHCCCCCCCCCCHHHCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCH
AAWYQYRQQESEA
HHHHHHHHHHCCC
>Mature Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVR
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEHHCCCCCEE
IVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQAKARDVQNFYFFCQHITLIP
EEECCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHH
TLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
HHHHHHHCCCCCCCEEECCCEEEEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCEEECCCHH
RFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGAC
HHCCCCCCCCCCHHHCCCHHHHHCHHHCCCCCCCCCCCCCCCCCCCHHHEEEEECCCCCH
AAWYQYRQQESEA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]