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The map label for this gene is hypE [H]

Identifier: 209396976

GI number: 209396976

Start: 3681383

End: 3682393

Strand: Direct

Name: hypE [H]

Synonym: ECH74115_3982

Alternate gene names: 209396976

Gene position: 3681383-3682393 (Clockwise)

Preceding gene: 209396571

Following gene: 209396082

Centisome position: 66.07

GC content: 57.67

Gene sequence:

>1011_bases
GTGAATAATATCCAACTCGCCCACGGTAGCGGCGGCCAGGCGATGCAGCAATTAATCAACAGCCTGTTTATGGAAGCCTT
TGCCAACCCGTGGCTGGCAGAGCAGGAAGATCAGGCACGTCTTGATCTGGCGCAGCTGGTAGCGGAAGGCGACCGTCTGG
CGTTCTCCACCGACAGTTACGTTATTGACCCGCTGTTCTTCCCTGGCGGTAATATCGGCAAGCTGGCGATTTGCGGCACC
GCGAATGACGTTGCGGTCAGTGGCGCTATTCCGCGCTATCTCTCCTGTGGCTTTATCCTCGAAGAAGGATTGCCGATGGA
GACACTGAAAGCCGTAGTGACCAGCATGGCAGAAACCGCCCGCACGGCAGGCATTGCCATCGTTACTGGCGATACTAAAG
TGGTGCAGCGCGGCGCGGCAGATAAACTGTTTATCAACACCGCGGGCATGGGCGCAATTCCGACGAATATTCACTGGGGC
GCACAGACGCTAACCGCAGGCGATATATTGCTGGTTAGCGGTACACTCGGCGACCACGGGGCGACTATCCTTAACCTGCG
TGAGCAGCTGGGGCTGGATGGCGAACTGGTCAGCGACTGCGCGGTGCTGACGCCGCTTATTCAGACGCTGCGTGACATTC
CCGGCGTGAAAGCGCTGCGTGATGCCACCCGTGGTGGTGTAAACGCGGTGGTTCATGAGTTCGCGGCAGCCTGCGGTTGC
GGTATTGAAATTTCTGAATCAGCGCTGCCGGTTAAACCTGCCGTGCGCGGCGTTTGCGAATTGCTGGGACTGGACGCCCT
GAACTTTGCCAACGAAGGCAAACTGGTGATCGCCGTTGAACGCAACGCGGCAGAGCAAGTGCTGGCAGCGTTACATTCCC
ATCCACTGGGGAAAGACGCGGCGCTGATTGGTGAAGTGGTGGAACGTAAAGGTGTTCGTCTTGCCGGTCTGTATGGCGTG
AAACGAACCCTCGATTTACCACACGCCGAACCGCTTCCGCGTATATGCTAA

Upstream 100 bases:

>100_bases
GTAACACCTGTAATCCTCAAACCGCGTTTGGTGCGCTGATGGTTTCCTCCGAAGGAGCGTGCGCCGCGTGGTATCAGTAT
CGTCAGCAGGAGAGTGAAGC

Downstream 100 bases:

>100_bases
TAAAATTCTAAATCTCCTATAGTTAGTCAATGACCTTTTGCACCGCTTTGCGGTGCTTTCCTGGAAGAACAAAATGTCAT
ATACACCGATGAGTGATCTC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWG
AQTLTAGDILLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC

Sequences:

>Translated_336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWG
AQTLTAGDILLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC
>Mature_336_residues
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWG
AQTLTAGDILLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=336, Percent_Identity=98.2142857142857, Blast_Score=667, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35155; Mature: 35155

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCE
VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA
EECEEECCCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHH
RTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWGAQTLTAGDILLVSGTLGDHG
HHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCC
ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA
CCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
HHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSY
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCE
VIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETA
EECEEECCCCCCCEEEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHH
RTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWGAQTLTAGDILLVSGTLGDHG
HHCCEEEEECCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCC
ATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDA
CCEECCCCCCCCHHHHHHHHHHCCHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
ALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
HHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]