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The map label for this gene is sopA [H]

Identifier: 209396431

GI number: 209396431

Start: 958579

End: 960591

Strand: Direct

Name: sopA [H]

Synonym: ECH74115_0947

Alternate gene names: 209396431

Gene position: 958579-960591 (Clockwise)

Preceding gene: 209400208

Following gene: 209398717

Centisome position: 17.2

GC content: 34.77

Gene sequence:

>2013_bases
ATGGATTGTTCAAAATGCAATGGTTATGCGACGATGTTATTAAATATGGTGCAGGGTTCTGACCCGGTTAATTTACTGGA
ATTACATGGTTTCCTTGAACATTTCGCATATTATGTTTCATTTGGCAAATTTAATGCTGGCCACCAGCGCTATAATGCAT
TTAAAAAATTCGTCAGTGAGATTTCGGAGATCAGCGCAAATGATATCAATATGACGATTAAAACCGGGCAATCCAGACAT
GAAAATGTGATCTCTATAAATATGAATGATGCAATTCCTCGTGATGAGAAAGGGATCACCGTTAGAATAGATAATATTAA
TGGAAAGAAAAACAACTCTAATTCATCAGATGTTTTTATTCCTTATGTAAATACATTTCCCGACCTCAAAAATAAAATAC
TCAGGATGAAAATTGAACTGACTGAAGGTAGTGGTTTTTCTAAAAGTCTTTCTGACAGTCAGATTGAGATGCATATTCTG
AGGACTGTTAATTCGCTAAATGTTGGCGAGAAATTGAATGATGATAATCTTGCAGATCATTCTATATTCACTAACGAATT
CTCTGTTATTATTCCGCCATCCTATTATGATGCAACTTCTGCAGTAAACGCTAATAATATTGTGAGAGAAAAACTATTTG
AAAGTGATAGTAAAGTTAAAGATATCGTCGATGATATGTCTAATCATGACGTGGAGAGCGAAAAAGATATATTTGTAATC
GGGGGGATGATAGAAAAACTGAATTCTCTGGCAGACGAATCTTTCAATGATAGTACTGATAACATACAAACAGTAAAAGA
TCTGTTAACGCAATTAACTGATGGCATGGAGCTCTTCGCGCTGCGGGACATAGTGGCATTCCCATCAACCATAATAGCAA
AATTAATAAAATCCCCACTTAATAGCGATCATGAACTTGTTATGCGCGCACTGGATACGTATCTGTGCTACTTCAGAAAT
AAAAATCTGAATAACAATGCGGAAATAATTAACTTTTTCCATGCCCTCTTTTTAAAGAGACCAGAGTTGATGGTTGCTGA
AAATTATAGATTTATTCAATTTATTGATTTGCTTTTTGAAAACGGAAATGTTGAAGAGAAAAACTTAGCATTTGACCTTT
ATCACAATTATCTTTCATTATCTGAAATAAAACAATTCGTTACTGAAGAAATTAAATTGAATTTCAATGAGCAGCAAGGA
TTGTTAGATAAAGATAATAAATGTTATATCCTGTTATCATCCGATAACTCTGGGCGAGTAATGCGCTTATCGCACCAGGC
GTTAATCTCAATGCTTGAGCCAGAGGTTAAGAAAAAGACTATCTGGAATAATTACTCTATTTATCCATCTTTGCAGGATA
CCCATGAAGTTGTCAGAGATGATCCAGAAACGATTTGTATGCGTGCATTTCCTTTATTTGCAAAAGGATGGGAATATGCG
CAGAAAAATAAGAAACATCAATTGATCCTCAATGCTCTTGGATTCAAAGGTTATATTCGTGATATATTTATGTCAGCAAT
AATGCGAAAAACAGATTTTGTGCTCGAATGCAATAATCAACCGACAGAACTTAATTCATCATTTTCCTCTTTGATGAACG
ATTCAGATCAATGGCAACAGCATACTCTGAAAGATAAACATTACGCTAATCTATTAACGATGCTGGATCTCAATGATGCC
AGTGAAAGTGATAAGTCTAAAATATTTTTCTGCCTGTCTGCCGTATTTGCAAATATTTCTCACAGTAATGTCTTTAACGG
TATTCCTGATGCGTCAAAAACTTTAAAACGTTATGCATTTGCTTTATTGGCGAAAGCTCATTCTTTAGATGAAAGTATGA
TAAGCAATCAAACTTTTAATACATACAAAACGGTATTGCTTGATTTCAATAATCTGTCTAATGAAGAGGCCAACCAGTTG
CGCATAAGTTCGTTATATCGTGATATGGTCCGCTATGCACAATATCGTTTTTCTAAAGTTTTATCCGAGTGGACGCCAGA
CGCATGGCTGTAA

Upstream 100 bases:

>100_bases
AATTTGCAGTACGAAAAGTTAAAAATGAGCGATTTCTGTAAGACTCCCCATTTTGCCAGGCTTATGATTCGCAGATCATT
CAAGTGCAAAGGAGCGATGT

Downstream 100 bases:

>100_bases
AGATCGCAGCAGAATAATGGCATTGATGGCCCTGGCTCAGGCCAGGGTCGGCAATACCGGTTCCTGCGAAGCGATGACGG
CGGCAATTGTAACCACGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Salmonella outer protein A; Secreted effector protein SopA [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSEISEISANDINMTIKTGQSRH
ENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFIPYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHIL
RTVNSLNVGEKLNDDNLADHSIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPLNSDHELVMRALDTYLCYFRN
KNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFENGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQG
LLDKDNKCYILLSSDNSGRVMRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQHTLKDKHYANLLTMLDLNDA
SESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAFALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQL
RISSLYRDMVRYAQYRFSKVLSEWTPDAWL

Sequences:

>Translated_670_residues
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSEISEISANDINMTIKTGQSRH
ENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFIPYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHIL
RTVNSLNVGEKLNDDNLADHSIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPLNSDHELVMRALDTYLCYFRN
KNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFENGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQG
LLDKDNKCYILLSSDNSGRVMRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQHTLKDKHYANLLTMLDLNDA
SESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAFALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQL
RISSLYRDMVRYAQYRFSKVLSEWTPDAWL
>Mature_670_residues
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSEISEISANDINMTIKTGQSRH
ENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFIPYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHIL
RTVNSLNVGEKLNDDNLADHSIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPLNSDHELVMRALDTYLCYFRN
KNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFENGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQG
LLDKDNKCYILLSSDNSGRVMRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQHTLKDKHYANLLTMLDLNDA
SESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAFALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQL
RISSLYRDMVRYAQYRFSKVLSEWTPDAWL

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell (By similarity). Note=Secreted via type III secretion system 1 (SPI-1 TTSS), and delivered into the host cell (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SopA E3 ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 76847; Mature: 76847

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSE
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ISEISANDINMTIKTGQSRHENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFI
HHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEE
PYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHILRTVNSLNVGEKLNDDNLADH
EECCCCHHHHHCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
SIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
CEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEE
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHC
NSDHELVMRALDTYLCYFRNKNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFE
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHC
NGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQGLLDKDNKCYILLSSDNSGRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCE
MRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
EEEHHHHHHHHHCCHHHHHHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCHHHH
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQ
HCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHHHH
HTLKDKHYANLLTMLDLNDASESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAF
HHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHH
ALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQLRISSLYRDMVRYAQYRFSKV
HHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSEWTPDAWL
HHHCCCCCCC
>Mature Secondary Structure
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSE
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
ISEISANDINMTIKTGQSRHENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFI
HHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEE
PYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHILRTVNSLNVGEKLNDDNLADH
EECCCCHHHHHCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
SIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
CEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCEEEE
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPL
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHC
NSDHELVMRALDTYLCYFRNKNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFE
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHC
NGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQGLLDKDNKCYILLSSDNSGRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCE
MRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
EEEHHHHHHHHHCCHHHHHHCCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHHCHHHH
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQ
HCCCCHHHHHHHHCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCHHHHH
HTLKDKHYANLLTMLDLNDASESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAF
HHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHH
ALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQLRISSLYRDMVRYAQYRFSKV
HHHHHHHHHHHHHHCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSEWTPDAWL
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA