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The map label for this gene is yagR

Identifier: 209395976

GI number: 209395976

Start: 335024

End: 337222

Strand: Reverse

Name: yagR

Synonym: ECH74115_0330

Alternate gene names: 209395976

Gene position: 337222-335024 (Counterclockwise)

Preceding gene: 209398590

Following gene: 209398027

Centisome position: 6.05

GC content: 59.53

Gene sequence:

>2199_bases
ATGAAATTTGATAAACCCGCAGGGGAAAACCCGATCGATCAGCTGAAGGTTGTCGGTCGTCCCCATGACCGCATCGACGG
ACCGCTGAAAACTACCGGCACGGCACGCTACGCCTACGAATGGCATGAAGAATCCCCCAACGCCGCCTATGGCTATATCG
TCGGTTCCGCCATTGCCAAAGGACGCCTCACCGCCCTTGATACGGACGCCGCGCAAAAAGCGCCGGGCGTACTGCCTGTC
ATTACCGCCAGTAACGCCGGGGCACTCAGTAAAGGCGACAAAAACACCGCCAGGCTGTTAGGCGGCCCCACTATTGAGCA
CTATCATCAGGCCATTGCTCTGGTAGTGGCCGAGACCTTCGAACAGGCGCGAGCGGCGGCCTCGCTGGTGCAGGCGCACT
ATCGCCGTAATAAAGGAGCTTACTCCCTGGCGGACGAAAAACAGGCCGTCAGTCAGCCGCCGGAAGACACGCCCGACAAG
AACGTCGGTGACTTTGACGGGGCTTTCTCCTCCGCTGCGGTGAAGATTGATGCTACCTACACGACCCCGGACCAGAGCCA
TATGGCGATGGAGCCGCATGCCTCGATGGCCGTCTGGGATGGAAATAAGCTTACTCTCTGGACCTCAAATCAGATGATTG
ACTGGTGCCGCACCGATCTGGCAAAAACGCTGAAAGTGCCCGTGGAGAATGTGCGTATTATCTCCCCGTATATCGGCGGA
GGGTTTGGCGGCAAGCTGTTCCTGAGAAGCGATGCGCTGCTGGCGGCCCTCGCCGCCCGAGCGGTGAAACGTCCGGTTAA
AGTGATGCTCCCCCGCCCCTCTATTCCCAATAACACCACGCACCGCCCCGCCACCCTTCAGCACTTGCGTATCGGTGCCG
ACCAGAGCGGGAAAATCACCGCTATCTCACATGAAAGCTGGTCTGGAAACCTGCCCGGCGGCACGCCGGAAACGGCGGTA
CAGCAAAGCGAATTACTCTACGCCGGGGCAAACCGTCATACCGGCCTGCGGCTCGCCACGCTTGATTTGCCGGAAGGGAA
CGCCATGCGTGCGCCCGGCGAAGCCCCCGGTCTGATGGCGCTCGAAATCGCGATCGACGAACTGGCGGAAAAAGCGGGCA
TCGATCCCGTCGAGTTTCGCATCCTGAATGACACTCAGATTGACCCCGCCGACCCGACGCGCCGCTTCTCTCGCCGTCAG
CTTATCGAGTGCTTGCGCACCGGAGCGGATAAATTTGGTTGGAAGCAGCGCAACGCCACACCCGGACAGGTGCGCGACGG
GGAGTGGCTAGTCGGCCACGGCGTCGCGGCGGGCTTTCGCAATAATCTGCTGGAAAAATCGGGGGCTCGGGTTCACCTCG
AACCAAACGGCACCGTTACCGTGGAAACGGACATGACCGACATTGGCACCGGCAGCTACACCATTCTGGCCCAGACGGCA
GCGGAAATGCTTGGCGTACCGCTGGAGCAGGTTGCGGTTCACCTCGGCGATTCCAGTTTCCCGGTTTCTGCGGGTTCTGG
TGGACAATGGGGCGCGAATACCTCCACCTCCGGCGTTTACGCCGCCTGTGTGAAGCTTCGCGAAATGATTGCCTCGGCAG
TCGGGTTTGATCCTGAGCAGTCGCAGTTTGCCGACGGCAAGATTACCAACGGTACCCGAAGCGCCATACTACATGAGGCC
ACCGCAGGCGGCAGACTGACAGCGGAAGAGAGCATTGAATTCGGAACACTGAGCAAGGAGTACCAGCAGTCGACCTTTGC
CGGGCATTTTGTGGAGGTCGGCGTGCATAGCGCGACGGGAGAAGTTCGGGTCCGGCGTATGCTCGCTGTGTGTGCTGCAG
GACGCATCCTGAATCCGAAAACTGCACGCAGCCAAGTCATTGGCGCAATGACTATGGGCATGGGCGCGGCACTGATGGAG
GAGCTGGCGGTGGATGACCGTTTGGGCTACTTCGTTAATCACGATATGGCGGGGTATGAGGTGCCGGTCCATGCGGATAT
CCCAAAACAGGAAGTGATTTTCCTGGATGATACCGACCCCATATCCTCCCCGATGAAGGCCAAAGGTGTCGGTGAGCTGG
GCCTGTGCGGCGTGAGCGCGGCTATCGCCAACGCGGTGTATAACGCCACCGGTATTCGGGTACGCGATTATCCCATCACT
CTGGATAAGCTGCTCGATAAGCTGCCGGATGTGGTTTAA

Upstream 100 bases:

>100_bases
CGCTGTTCGCCAGCGCCCATCCCACCGCTGAAAACACCTTTAAACTCCTGTTGGCGAAGCGAACGCTTGCCTCCGTACTG
GCTGAAGCGAGGGCACAAGC

Downstream 100 bases:

>100_bases
GGAGGAACAATGTCATACCCGCTTTTTGATAAAGACGAACACTGGCATAAGCCAGAGCAGGCGTTTCTCACCGATGACCA
CCGGACCATTCTGCGCTTCG

Product: xanthine dehydrogenase family protein, molybdopterin-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLPV
ITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFSSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQSQFADGKITNGTRSAILHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Sequences:

>Translated_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLPV
ITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFSSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQSQFADGKITNGTRSAILHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV
>Mature_732_residues
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLPV
ITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFSSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQSQFADGKITNGTRSAILHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV

Specific function: Unknown

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family

Homologues:

Organism=Homo sapiens, GI91823271, Length=743, Percent_Identity=26.2449528936743, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI71773480, Length=743, Percent_Identity=24.6298788694482, Blast_Score=135, Evalue=2e-31,
Organism=Escherichia coli, GI1786478, Length=732, Percent_Identity=98.6338797814208, Blast_Score=1486, Evalue=0.0,
Organism=Escherichia coli, GI1789230, Length=760, Percent_Identity=28.6842105263158, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789246, Length=805, Percent_Identity=25.8385093167702, Blast_Score=190, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17540638, Length=721, Percent_Identity=25.5201109570042, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32566215, Length=557, Percent_Identity=23.3393177737882, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=735, Percent_Identity=21.3605442176871, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24647199, Length=724, Percent_Identity=24.0331491712707, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24647195, Length=743, Percent_Identity=24.4952893674293, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24647193, Length=729, Percent_Identity=24.5541838134431, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24647197, Length=734, Percent_Identity=24.5231607629428, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17737937, Length=728, Percent_Identity=24.1758241758242, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24647201, Length=714, Percent_Identity=24.3697478991597, Blast_Score=111, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YAGR_ECO57 (Q8X6J4)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B90668
- PIR:   E85518
- RefSeq:   NP_286001.1
- RefSeq:   NP_308341.1
- ProteinModelPortal:   Q8X6J4
- SMR:   Q8X6J4
- EnsemblBacteria:   EBESCT00000026190
- EnsemblBacteria:   EBESCT00000057618
- GeneID:   914413
- GeneID:   957138
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0350
- KEGG:   ecs:ECs0314
- GeneTree:   EBGT00050000009267
- HOGENOM:   HBG705921
- OMA:   TIQRIRI
- ProtClustDB:   CLSK879611
- BioCyc:   ECOL83334:ECS0314-MONOMER
- InterPro:   IPR000674
- InterPro:   IPR008274
- Gene3D:   G3DSA:3.30.365.10
- Gene3D:   G3DSA:3.90.1170.50

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2; SSF56003 Ald_xan_DH_mo_bd; SSF54665 Aldxan_dh_hamm

EC number: =1.17.1.4

Molecular weight: Translated: 78136; Mature: 78136

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCEEEEEEECCCCCCCEEEHEEHHHHHC
GRLTALDTDAAQKAPGVLPVITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETF
CCEEEECCCHHHHCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDKNVGDFDGAFSSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSAILHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCHHHHHEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC
>Mature Secondary Structure
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAK
CCCCCCCCCCHHHHHEECCCCCHHCCCCCCCCCCEEEEEEECCCCCCCEEEHEEHHHHHC
GRLTALDTDAAQKAPGVLPVITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETF
CCEEEECCCHHHHCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
EQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDKNVGDFDGAFSSAAVKIDATY
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEEE
TTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
CCCCCCCEEECCCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCC
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKIT
CCCCEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHEEECCCCCCCEE
AISHESWSGNLPGGTPETAVQQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMA
EEECCCCCCCCCCCCCHHHHHHHHEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCEEE
LEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQLIECLRTGADKFGWKQRNAT
EHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
PGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
CCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCEEEHHHHH
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQ
HHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
SQFADGKITNGTRSAILHEATAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATG
CCCCCCCCCCCHHHHHEEECCCCCEEEHHCCCCCCCCCHHHHHHHHCCEEEEEECCCCCH
EVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYE
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCE
VPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
EEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCC
LDKLLDKLPDVV
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796