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The map label for this gene is atpA [H]

Identifier: 209696445

GI number: 209696445

Start: 3316498

End: 3318039

Strand: Reverse

Name: atpA [H]

Synonym: VSAL_I3061

Alternate gene names: 209696445

Gene position: 3318039-3316498 (Counterclockwise)

Preceding gene: 209696446

Following gene: 209696444

Centisome position: 99.79

GC content: 43.45

Gene sequence:

>1542_bases
ATGCAACTTAATTCCACGGAAATTAGCGATCTGATCAAACAACGTATTGAAAAATTCAACGTTGCAAGTGAAGCTCGTAA
TGAAGGTACAATCGTTTCTGTAAGCGACGGTATTATTCGTATCCACGGCCTTGCTGATGTTATGCAAGGCGAAATGATTG
AATTACCTGGTGGCCATTACGCACTAGCACTTAACCTTGAGCGTGACTCAGTGGGTGCTGTTGTTATGGGACCTTATGCT
GACTTACAAGAAGGCATGAAAGTTACAGGTACTGGTCGTATCCTTGAAGTACCAGTAGGCCCAGAAATGTTAGGTCGTGT
TGTAAACACACTTGGCGAGCCTATTGATGGTAAAGGACCTATTGACGCGAAATTAACTTCTCCAGTAGAAGTGATTGCAC
CTGGTGTAATCGATCGTAAATCAGTAGACCAACCACTACAAACTGGCTATAAGTCAGTTGACTCAATGATCCCAATCGGC
CGAGGTCAGCGTGAGCTAATCATCGGTGACCGTCAGACTGGTAAAACAGCAATGGCGATCGATGCGATCATTAACCAGAA
AAATTCTGGTATCTTCGCTATTTATGTTGCAATTGGCCAAAAGGCATCAACAATTGCTAACGTAGTTCGTAAACTGGAAG
AGCATGGTGCACTAGCGAATACTATCGTTGTTGTTGCTTCTGCTTCTGAATCTGCTGCGCTGCAATATCTTGCACCGTAT
GCTGGTTGTGCGATGGGTGAATACTTCCGTGATCGCGGTGAAGATGCTCTGATTGTTTATGATGATCTATCTAAGCAAGC
AGTAGCTTATCGTCAGATTTCTCTACTATTGAAACGTCCACCGGGCCGTGAAGCGTTCCCTGGCGATGTATTCTATTTAC
ACTCCCGTCTACTAGAGCGTGCTGCTCGTGTAAGCGTAGCGTACGTTGAGAAATTCACCAATGGTGAAGTGAAAGGTAAA
ACTGGTTCTTTGACTGCTCTACCTATCATCGAAACTCAAGCTGGTGATGTATCTGCATTTGTACCAACTAACGTAATTTC
GATTACTGATGGTCAGATCTTCCTACAAACAGAACTGTTCACCGCTGGTGTTCGTCCTGCTGTAGATCCAGGTATCTCTG
TATCTCGTGTTGGTGGTGCTGCGCAAACTAAGATCATTAAGAAACTGTCTGGTGGTATTCGTACTGCTCTTGCACAGTAT
CGTGAACTTGCAGCATTTGCTCAGTTCTCTTCTGATCTTGATGAAGCGACTAAAAAGCAACTTGATCATGGTGAGAAAGT
AACTGAGCTTATGAAACAAAAACAGTACGCTCCAATGTCTGTTTTTGATCAAGCATTAGTTATCTTTACAGCTGAGAAAG
GCTACTTGAATGATGTTGAGCTTAAGAAGCTTGCTGATTTTGAAGAAGCTCTGCTGTCGTATGCTCGTGGTCAATTTGCC
GATCTAGCAAAAGAGATCGACTCATCGGGTGCTTGGAATAAAGAAATTGAAGATCAGTTCGTGAAACTGGTTGAAGATTT
CAAAGCAACCCAGACCTGGTAA

Upstream 100 bases:

>100_bases
GGGGTCATAATTCGAGCCGGAGACCTAGTCATTGATAACTCAGTTAGAGGCCGTTTGAGCCGACTGAGTGAAACATTGCA
GTCTTGATGGGGAATGGTGC

Downstream 100 bases:

>100_bases
TTCGTTGGTGACCTGTTATGGGTCACCCGAAAACGGAGAGTAACGATGGCCGGTGCAAAAGAGATTCGTAGCAAGATCGG
GAGTGTGAAAAGCACTCAAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISDLIKQRIEKFNVASEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGHYALALNLERDSVGAVVMGPYA
DLQEGMKVTGTGRILEVPVGPEMLGRVVNTLGEPIDGKGPIDAKLTSPVEVIAPGVIDRKSVDQPLQTGYKSVDSMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIFAIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVSVAYVEKFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFTAGVRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATKKQLDHGEKVTELMKQKQYAPMSVFDQALVIFTAEKGYLNDVELKKLADFEEALLSYARGQFA
DLAKEIDSSGAWNKEIEDQFVKLVEDFKATQTW

Sequences:

>Translated_513_residues
MQLNSTEISDLIKQRIEKFNVASEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGHYALALNLERDSVGAVVMGPYA
DLQEGMKVTGTGRILEVPVGPEMLGRVVNTLGEPIDGKGPIDAKLTSPVEVIAPGVIDRKSVDQPLQTGYKSVDSMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIFAIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVSVAYVEKFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFTAGVRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATKKQLDHGEKVTELMKQKQYAPMSVFDQALVIFTAEKGYLNDVELKKLADFEEALLSYARGQFA
DLAKEIDSSGAWNKEIEDQFVKLVEDFKATQTW
>Mature_513_residues
MQLNSTEISDLIKQRIEKFNVASEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGHYALALNLERDSVGAVVMGPYA
DLQEGMKVTGTGRILEVPVGPEMLGRVVNTLGEPIDGKGPIDAKLTSPVEVIAPGVIDRKSVDQPLQTGYKSVDSMIPIG
RGQRELIIGDRQTGKTAMAIDAIINQKNSGIFAIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVSVAYVEKFTNGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFTAGVRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQY
RELAAFAQFSSDLDEATKKQLDHGEKVTELMKQKQYAPMSVFDQALVIFTAEKGYLNDVELKKLADFEEALLSYARGQFA
DLAKEIDSSGAWNKEIEDQFVKLVEDFKATQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=513, Percent_Identity=55.1656920077973, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI4757810, Length=513, Percent_Identity=55.1656920077973, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI32189394, Length=466, Percent_Identity=25.5364806866953, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI19913428, Length=315, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913426, Length=314, Percent_Identity=26.7515923566879, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913424, Length=338, Percent_Identity=25.7396449704142, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=82.0662768031189, Blast_Score=863, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=362, Percent_Identity=25.9668508287293, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788251, Length=383, Percent_Identity=24.5430809399478, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=54.7572815533981, Blast_Score=550, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=54.7572815533981, Blast_Score=549, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.6504854368932, Blast_Score=509, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=377, Percent_Identity=26.790450928382, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=460, Percent_Identity=24.3478260869565, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=314, Percent_Identity=27.7070063694268, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=63.8297872340426, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=26.3358778625954, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.411306042885, Blast_Score=550, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6322581, Length=461, Percent_Identity=26.8980477223427, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319603, Length=314, Percent_Identity=26.7515923566879, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.2801556420233, Blast_Score=552, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24638766, Length=413, Percent_Identity=25.6658595641646, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI281361666, Length=305, Percent_Identity=26.8852459016393, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24646341, Length=305, Percent_Identity=26.8852459016393, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17136796, Length=305, Percent_Identity=26.8852459016393, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28574560, Length=321, Percent_Identity=25.5451713395639, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24583992, Length=334, Percent_Identity=26.0479041916168, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583988, Length=263, Percent_Identity=28.1368821292776, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583986, Length=263, Percent_Identity=28.1368821292776, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583984, Length=263, Percent_Identity=28.1368821292776, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129479, Length=239, Percent_Identity=28.0334728033473, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55515; Mature: 55515

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISDLIKQRIEKFNVASEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGHY
CCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEECCCCCE
ALALNLERDSVGAVVMGPYADLQEGMKVTGTGRILEVPVGPEMLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCHHHHHCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCC
IDAKLTSPVEVIAPGVIDRKSVDQPLQTGYKSVDSMIPIGRGQRELIIGDRQTGKTAMAI
CCCCCCCCHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKNSGIFAIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSVAYVEKFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHH
TAGVRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFSSDLDEATKKQ
HCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGEKVTELMKQKQYAPMSVFDQALVIFTAEKGYLNDVELKKLADFEEALLSYARGQFA
HCCCHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHH
DLAKEIDSSGAWNKEIEDQFVKLVEDFKATQTW
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISDLIKQRIEKFNVASEARNEGTIVSVSDGIIRIHGLADVMQGEMIELPGGHY
CCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEEEECHHHHHCCCEEECCCCCE
ALALNLERDSVGAVVMGPYADLQEGMKVTGTGRILEVPVGPEMLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCHHHHHCCCEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCCC
IDAKLTSPVEVIAPGVIDRKSVDQPLQTGYKSVDSMIPIGRGQRELIIGDRQTGKTAMAI
CCCCCCCCHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
DAIINQKNSGIFAIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHH
AGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLER
HHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSVAYVEKFTNGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEEHH
TAGVRPAVDPGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFSSDLDEATKKQ
HCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDHGEKVTELMKQKQYAPMSVFDQALVIFTAEKGYLNDVELKKLADFEEALLSYARGQFA
HCCCHHHHHHHHHHCCCCHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHH
DLAKEIDSSGAWNKEIEDQFVKLVEDFKATQTW
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]