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The map label for this gene is nahR [H]

Identifier: 209696365

GI number: 209696365

Start: 3216466

End: 3217407

Strand: Direct

Name: nahR [H]

Synonym: VSAL_I2971

Alternate gene names: 209696365

Gene position: 3216466-3217407 (Clockwise)

Preceding gene: 209696364

Following gene: 209696369

Centisome position: 96.73

GC content: 39.6

Gene sequence:

>942_bases
ATGGAATTAGAAGAAGTTTATCGTCGTGATTTAAATTTATTGGTTGCGTTAAAAGTTCTGTTAGAAGAAAACAGCGTTAG
CCAAGCGGCGATTCGCCTGAATTTAAGTCAATCAGCGATGAGTCGGGTGCTGGGTCGGCTGCGTGATTTACTGGGCGATC
CTTTATTTACTCGACAAGGGCAGCATCTGGTTCCAACAGAAAAAGCATTAGAAATTTGTGCGCAAATAAACCAACCTTTA
GAGTCGTTACGTCAGTTGCTTACGCCCAGCGATTTTACCCCTATGCATTGTGATCAACATTTTTTGATCGCAACGACCGA
TTATGCAATGCAGACAATTCTACCTTATGCATTACCTAAGATTTACGAACAAGCCCCAAATATATCTTTAGAGTTTACGT
CTCTTAATCATGAAAACTTGTTTAAACAATTGAGTACAGAGAAAGTCGACATGGCAATTTGTCGTCCTATCGGGTCCGTA
TCTCCATTAAAACAAGAAGTATTAGGGCAGGTTGGAGTGTTATGTCTTTTATCAAAGCATCATCCGTTGTCTCATGCATT
ACTGACATTGGACGATTATTTATCGTATCCACATGCGATGATTGCGATCAGTGATGGTGTAAAAGCATTGTTAGATACCG
CGTTGATTGGCCAACGAGATCGCAAACAAGTATTAAGGGCTTATCATTTAGAAGCGGCTTTAGCGATTGTCGACCGGATG
CCATTAATTATTACGGTTCCAGCCGATTTAGCTTATTTAGTTGCTGAACGTTATGACTTAGTGATTAAACCATTACCTTT
TGAATTTACACCGTTTGATTATTCATTAATTTGGCATTCTCGTTGTGATACATCGCCCGCGCAAAGTTGGTTACGTAGAG
TTGTAAAAGAAGAGTGTGGGAAGTTAATTGAAAAACGCATTGAAGATATTGGCTTTGTTTGA

Upstream 100 bases:

>100_bases
ATTAAATAAGAGGTAGGTGAAAAGCGGGATTTTTTTTATCTATAAAACCGTTAAAATGTCGGTAATGCCATAAAGGCGTT
CTCTATTGATGGGTTAGGTT

Downstream 100 bases:

>100_bases
TTGGTGTTGCAGAGACTAAGCATAAAAAGGCAGCGATTAAGCTGCCTTTAATTTACTGATGTTTTCACATTAACACCAAG
CTAGGTAGGGCTCAGCGTTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MELEEVYRRDLNLLVALKVLLEENSVSQAAIRLNLSQSAMSRVLGRLRDLLGDPLFTRQGQHLVPTEKALEICAQINQPL
ESLRQLLTPSDFTPMHCDQHFLIATTDYAMQTILPYALPKIYEQAPNISLEFTSLNHENLFKQLSTEKVDMAICRPIGSV
SPLKQEVLGQVGVLCLLSKHHPLSHALLTLDDYLSYPHAMIAISDGVKALLDTALIGQRDRKQVLRAYHLEAALAIVDRM
PLIITVPADLAYLVAERYDLVIKPLPFEFTPFDYSLIWHSRCDTSPAQSWLRRVVKEECGKLIEKRIEDIGFV

Sequences:

>Translated_313_residues
MELEEVYRRDLNLLVALKVLLEENSVSQAAIRLNLSQSAMSRVLGRLRDLLGDPLFTRQGQHLVPTEKALEICAQINQPL
ESLRQLLTPSDFTPMHCDQHFLIATTDYAMQTILPYALPKIYEQAPNISLEFTSLNHENLFKQLSTEKVDMAICRPIGSV
SPLKQEVLGQVGVLCLLSKHHPLSHALLTLDDYLSYPHAMIAISDGVKALLDTALIGQRDRKQVLRAYHLEAALAIVDRM
PLIITVPADLAYLVAERYDLVIKPLPFEFTPFDYSLIWHSRCDTSPAQSWLRRVVKEECGKLIEKRIEDIGFV
>Mature_313_residues
MELEEVYRRDLNLLVALKVLLEENSVSQAAIRLNLSQSAMSRVLGRLRDLLGDPLFTRQGQHLVPTEKALEICAQINQPL
ESLRQLLTPSDFTPMHCDQHFLIATTDYAMQTILPYALPKIYEQAPNISLEFTSLNHENLFKQLSTEKVDMAICRPIGSV
SPLKQEVLGQVGVLCLLSKHHPLSHALLTLDDYLSYPHAMIAISDGVKALLDTALIGQRDRKQVLRAYHLEAALAIVDRM
PLIITVPADLAYLVAERYDLVIKPLPFEFTPFDYSLIWHSRCDTSPAQSWLRRVVKEECGKLIEKRIEDIGFV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=25.9868421052632, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790147, Length=307, Percent_Identity=27.3615635179153, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789204, Length=259, Percent_Identity=23.1660231660232, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35435; Mature: 35435

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELEEVYRRDLNLLVALKVLLEENSVSQAAIRLNLSQSAMSRVLGRLRDLLGDPLFTRQG
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCC
QHLVPTEKALEICAQINQPLESLRQLLTPSDFTPMHCDQHFLIATTDYAMQTILPYALPK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
IYEQAPNISLEFTSLNHENLFKQLSTEKVDMAICRPIGSVSPLKQEVLGQVGVLCLLSKH
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
HPLSHALLTLDDYLSYPHAMIAISDGVKALLDTALIGQRDRKQVLRAYHLEAALAIVDRM
CCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PLIITVPADLAYLVAERYDLVIKPLPFEFTPFDYSLIWHSRCDTSPAQSWLRRVVKEECG
CEEEECCHHHHHHHHHHHCEEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
KLIEKRIEDIGFV
HHHHHHHHHHCCC
>Mature Secondary Structure
MELEEVYRRDLNLLVALKVLLEENSVSQAAIRLNLSQSAMSRVLGRLRDLLGDPLFTRQG
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCC
QHLVPTEKALEICAQINQPLESLRQLLTPSDFTPMHCDQHFLIATTDYAMQTILPYALPK
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
IYEQAPNISLEFTSLNHENLFKQLSTEKVDMAICRPIGSVSPLKQEVLGQVGVLCLLSKH
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
HPLSHALLTLDDYLSYPHAMIAISDGVKALLDTALIGQRDRKQVLRAYHLEAALAIVDRM
CCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PLIITVPADLAYLVAERYDLVIKPLPFEFTPFDYSLIWHSRCDTSPAQSWLRRVVKEECG
CEEEECCHHHHHHHHHHHCEEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
KLIEKRIEDIGFV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]