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The map label for this gene is dtd

Identifier: 209696334

GI number: 209696334

Start: 3182875

End: 3183309

Strand: Reverse

Name: dtd

Synonym: VSAL_I2937

Alternate gene names: 209696334

Gene position: 3183309-3182875 (Counterclockwise)

Preceding gene: 209696335

Following gene: 209696333

Centisome position: 95.73

GC content: 41.61

Gene sequence:

>435_bases
GTGATAGCACTGATCCAAAGAGTAAGTGAAGCCTCAGTACGTGTTGATGGCGAGATCACAGGTGAAATTAATCAAGGTTT
ATTAATATTACTTGGTGTTGAAAGAGAAGACGATGAAGCGAAAGCGAAGCGTTTAGTGGAAAGAGTTCTGACTTATCGTA
TCTTTGAAGACGATGAAGGGAAAATGAACTTAAATGTGCAACAAGTGAATGGTAGCGTATTGGTTGTTTCTCAGTTTACT
TTACCTGCAGATACGAAAAAGGGAACGCGTCCAGGGTTTTCTAAAGGTGCGAACCCTATCGACGCTGAGCGCTTATATGA
TCACTTCTCTGATTTATGTGACGAAAAATTAACCACGCAAAGAGGCCGTTTTGCGGCTGATATGAAAGTATCGTTAGTGA
ATGATGGGCCTGTGACATTTTGGTTGCAGGTGTAG

Upstream 100 bases:

>100_bases
AGTCTGGGTGAATCCGATCAGTGGTTGATAGATAAAATAAATACGCATGTATTTGATGCTGAGAATACGGTATTAACAGA
ATCAAAAGGATTAACAGAAA

Downstream 100 bases:

>100_bases
AGCAGGGGCGAGAATTAAAGACGCTTCGCTCGAGGGCAAGGAAAAGCCAAAGAGTAGAATTCAGAGGTGTTTACTTTTAG
CTCCTTCCCCTTACTAAGGG

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEGKMNLNVQQVNGSVLVVSQFT
LPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQRGRFAADMKVSLVNDGPVTFWLQV

Sequences:

>Translated_144_residues
MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEGKMNLNVQQVNGSVLVVSQFT
LPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQRGRFAADMKVSLVNDGPVTFWLQV
>Mature_144_residues
MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEGKMNLNVQQVNGSVLVVSQFT
LPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQRGRFAADMKVSLVNDGPVTFWLQV

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=36.734693877551, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=73.1034482758621, Blast_Score=216, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=37.7622377622378, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.8918918918919, Blast_Score=109, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=35.6164383561644, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_ALISL (B6EGQ6)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264265.1
- GeneID:   6987981
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2937
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16068; Mature: 16068

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEG
CHHHHHHHCCCCEEECCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCC
KMNLNVQQVNGSVLVVSQFTLPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQ
EEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
RGRFAADMKVSLVNDGPVTFWLQV
CCCEEECEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEG
CHHHHHHHCCCCEEECCEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEEEECCCC
KMNLNVQQVNGSVLVVSQFTLPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQ
EEEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
RGRFAADMKVSLVNDGPVTFWLQV
CCCEEECEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA