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The map label for this gene is glpG [H]

Identifier: 209696297

GI number: 209696297

Start: 3144389

End: 3145228

Strand: Reverse

Name: glpG [H]

Synonym: VSAL_I2898

Alternate gene names: 209696297

Gene position: 3145228-3144389 (Counterclockwise)

Preceding gene: 209696298

Following gene: 209696295

Centisome position: 94.59

GC content: 39.17

Gene sequence:

>840_bases
ATGCATCGATTGATCGCGTTATCAAATCCAAGAGCTGGTCAGGCCTTTATTGATTATATGGCTTCACGTCATATTGATCT
TCGTATGATGCCAGAAGGGGAAGGCCAGTTTGCGTTATGGGTAGTGTCTGATGATACTTATCTATTGGAAGTTGAATCGG
AACTACAAGCGTTTTTAAAAGATCCTAATGCGACAAAATATCAATCAGCATCATGGGATATGGCGGATACTCGTACTGCT
AAATTTTCTTATTCTTCACCCAATATTATGAAGATGGTAAAAGCCAAAGCCGGTGTGTTTACGTTATTCATCATGGTGAG
CTGTATTGTTATTTTTGCTTTGCAGCAATTTGGTTGGAATAATTCAGTCTTTCAATTATTGCACTTCCCTGAAAACCAAG
GGCAAAGCATTGAGATATGGCGTTGGTTCTCTCATGCGTTACTTCACTTTTCAGCTACTCACATTATTTTTAATTTATTG
TGGTGGTGGCAGCTTGGTGGAGACATTGAATTACGTTTAGGTCGAACAAAACTGGTTCAATTGTTCTTGTTTTCTGCTTT
ATTTTCAGGACTTGGACAGTTTTGGATAGATGGTGCTAACTTTGGTGGTCTATCTGGTGTTGTGTATGCGTTATTAGGCT
ATTCGTGGTTTATTGGTTGGTTGGCTCCTGAAAGAGGTATCTCAGTGTCTAAACCTATCGTAGGGTTTATGCTGATATGG
ATCATTCTTGGGTATGTTCAGCCTTTTATGGCGATTGCGAATACTGCACATTTAGTGGGATTGATAACCGGTTGTGCTTT
TGCAGCAATTGACAGTCAATTCAAGTTTAAAAAAGCGTAA

Upstream 100 bases:

>100_bases
CAATATTTAATTAACCAAGGCTATGAAGAAGTTTATAGTGTTGATGGTGGTTTTGAAGGCTGGAATAAAGCAGGCTTGCC
CGTAGAAAAGTAGAGAATTT

Downstream 100 bases:

>100_bases
TAAAACGAAATAAAAATAGAGCAAGAAGATTATCTCTTGCCCTATTTTTTTCTTTATTGGTAGATATATTTAGTAAACAA
TAAATCCACAGCTAATGTTT

Product: integral membrane protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MHRLIALSNPRAGQAFIDYMASRHIDLRMMPEGEGQFALWVVSDDTYLLEVESELQAFLKDPNATKYQSASWDMADTRTA
KFSYSSPNIMKMVKAKAGVFTLFIMVSCIVIFALQQFGWNNSVFQLLHFPENQGQSIEIWRWFSHALLHFSATHIIFNLL
WWWQLGGDIELRLGRTKLVQLFLFSALFSGLGQFWIDGANFGGLSGVVYALLGYSWFIGWLAPERGISVSKPIVGFMLIW
IILGYVQPFMAIANTAHLVGLITGCAFAAIDSQFKFKKA

Sequences:

>Translated_279_residues
MHRLIALSNPRAGQAFIDYMASRHIDLRMMPEGEGQFALWVVSDDTYLLEVESELQAFLKDPNATKYQSASWDMADTRTA
KFSYSSPNIMKMVKAKAGVFTLFIMVSCIVIFALQQFGWNNSVFQLLHFPENQGQSIEIWRWFSHALLHFSATHIIFNLL
WWWQLGGDIELRLGRTKLVQLFLFSALFSGLGQFWIDGANFGGLSGVVYALLGYSWFIGWLAPERGISVSKPIVGFMLIW
IILGYVQPFMAIANTAHLVGLITGCAFAAIDSQFKFKKA
>Mature_279_residues
MHRLIALSNPRAGQAFIDYMASRHIDLRMMPEGEGQFALWVVSDDTYLLEVESELQAFLKDPNATKYQSASWDMADTRTA
KFSYSSPNIMKMVKAKAGVFTLFIMVSCIVIFALQQFGWNNSVFQLLHFPENQGQSIEIWRWFSHALLHFSATHIIFNLL
WWWQLGGDIELRLGRTKLVQLFLFSALFSGLGQFWIDGANFGGLSGVVYALLGYSWFIGWLAPERGISVSKPIVGFMLIW
IILGYVQPFMAIANTAHLVGLITGCAFAAIDSQFKFKKA

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=279, Percent_Identity=40.1433691756272, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31571; Mature: 31571

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRLIALSNPRAGQAFIDYMASRHIDLRMMPEGEGQFALWVVSDDTYLLEVESELQAFLK
CCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCEEEEEEHHHHHHHHC
DPNATKYQSASWDMADTRTAKFSYSSPNIMKMVKAKAGVFTLFIMVSCIVIFALQQFGWN
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSVFQLLHFPENQGQSIEIWRWFSHALLHFSATHIIFNLLWWWQLGGDIELRLGRTKLVQ
CCHHHEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
LFLFSALFSGLGQFWIDGANFGGLSGVVYALLGYSWFIGWLAPERGISVSKPIVGFMLIW
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IILGYVQPFMAIANTAHLVGLITGCAFAAIDSQFKFKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHRLIALSNPRAGQAFIDYMASRHIDLRMMPEGEGQFALWVVSDDTYLLEVESELQAFLK
CCCEEEECCCCCHHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCEEEEEEHHHHHHHHC
DPNATKYQSASWDMADTRTAKFSYSSPNIMKMVKAKAGVFTLFIMVSCIVIFALQQFGWN
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NSVFQLLHFPENQGQSIEIWRWFSHALLHFSATHIIFNLLWWWQLGGDIELRLGRTKLVQ
CCHHHEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
LFLFSALFSGLGQFWIDGANFGGLSGVVYALLGYSWFIGWLAPERGISVSKPIVGFMLIW
HHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IILGYVQPFMAIANTAHLVGLITGCAFAAIDSQFKFKKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA