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The map label for this gene is accB [H]

Identifier: 209696239

GI number: 209696239

Start: 3074450

End: 3074905

Strand: Direct

Name: accB [H]

Synonym: VSAL_I2835

Alternate gene names: 209696239

Gene position: 3074450-3074905 (Clockwise)

Preceding gene: 209696238

Following gene: 209696240

Centisome position: 92.46

GC content: 45.83

Gene sequence:

>456_bases
ATGGATATCCGTAAAATTAAGAAACTGATTGAACTAGTTGAAGAGTCTGGCATTGCTGAACTTGAGATTTCTGAAGGTGA
AGAATCTGTACGTATCAGTCGCGCTGTAGCTCCTATGGCTCAACTAACACCAATGCAACCATACCCAGCGCCAGTTGCTC
CTATGGCTGCACCAGTAGCCGCTCCGGTAGCTGCAGTTGAAGCTCCAGTAGCCGTAGCCGCAGGTCATAAAGTGTGTTCT
CCAATGGTTGGCACTTTCTACGGTGCTTCAAGCCCTGATGCAAAACCATTTGTTAAAGTTGGCCAACAAGTTACTGCTGG
CGATACATTATGTATCGTTGAAGCTATGAAAATGATGAACCAAATCGAAGCAGATAAGTCTGGTGTAGTTACTGCTATCC
TAGCTGAAGACGGCCAACCGGTTGAATTCGACCAGCCACTTGTTGTGATCGAATAA

Upstream 100 bases:

>100_bases
TTGCGGTTTAGGCGCAGATGGCTACGAATTTGCTTTGAAGGCGGCAGTAAAACGTCTGCGTTCAAATTGATCACTGAATA
TAAACAGAAGAGATTACACA

Downstream 100 bases:

>100_bases
ATAGAGGTCACTATGTTAGATAAATTAGTTATCGCAAACCGTGGTGAAATTGCACTGCGTATCTTGCGAGCATGTAAAGA
GCTTGGCATCAAAACGGTTG

Product: acetyl-CoA carboxylase biotin carboxyl carrier protein subunit

Products: ADP; phosphate; malonyl-CoA

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MDIRKIKKLIELVEESGIAELEISEGEESVRISRAVAPMAQLTPMQPYPAPVAPMAAPVAAPVAAVEAPVAVAAGHKVCS
PMVGTFYGASSPDAKPFVKVGQQVTAGDTLCIVEAMKMMNQIEADKSGVVTAILAEDGQPVEFDQPLVVIE

Sequences:

>Translated_151_residues
MDIRKIKKLIELVEESGIAELEISEGEESVRISRAVAPMAQLTPMQPYPAPVAPMAAPVAAPVAAVEAPVAVAAGHKVCS
PMVGTFYGASSPDAKPFVKVGQQVTAGDTLCIVEAMKMMNQIEADKSGVVTAILAEDGQPVEFDQPLVVIE
>Mature_151_residues
MDIRKIKKLIELVEESGIAELEISEGEESVRISRAVAPMAQLTPMQPYPAPVAPMAAPVAAPVAAVEAPVAVAAGHKVCS
PMVGTFYGASSPDAKPFVKVGQQVTAGDTLCIVEAMKMMNQIEADKSGVVTAILAEDGQPVEFDQPLVVIE

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=157, Percent_Identity=71.3375796178344, Blast_Score=194, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: 6.4.1.2

Molecular weight: Translated: 15799; Mature: 15799

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRKIKKLIELVEESGIAELEISEGEESVRISRAVAPMAQLTPMQPYPAPVAPMAAPVA
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
APVAAVEAPVAVAAGHKVCSPMVGTFYGASSPDAKPFVKVGQQVTAGDTLCIVEAMKMMN
HHHHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
QIEADKSGVVTAILAEDGQPVEFDQPLVVIE
HHCCCCCCCEEEEEECCCCCCCCCCCEEEEC
>Mature Secondary Structure
MDIRKIKKLIELVEESGIAELEISEGEESVRISRAVAPMAQLTPMQPYPAPVAPMAAPVA
CCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
APVAAVEAPVAVAAGHKVCSPMVGTFYGASSPDAKPFVKVGQQVTAGDTLCIVEAMKMMN
HHHHHHHCCHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
QIEADKSGVVTAILAEDGQPVEFDQPLVVIE
HHCCCCCCCEEEEEECCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; acetyl-CoA; HCO3-

Specific reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]