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The map label for this gene is aroQ

Identifier: 209696238

GI number: 209696238

Start: 3073970

End: 3074419

Strand: Direct

Name: aroQ

Synonym: VSAL_I2834

Alternate gene names: 209696238

Gene position: 3073970-3074419 (Clockwise)

Preceding gene: 209696237

Following gene: 209696239

Centisome position: 92.45

GC content: 40.67

Gene sequence:

>450_bases
ATGTCTACTCAATCGCGAATTTTAATACTAAATGGCCCTAATCTTAATTTATTAGGACTTCGAGAGCCGGCACATTACGG
CAGTCAAAATTTAGAACAGATCGTTAACGCTCTGACCATTCAAGCAACTGCATTGAATGTCGAACTTGAGCATTTACAAT
CTAACCGTGAATATGAGTTGATTGAAGCGATCCATAATGCTTATCAACGTATTGATTTCATTATTATCAATCCAGCAGCG
TTTACACATACCAGTGTCGCTTTACGTGATGCTCTGCTTGGGGTTGATATTCCTTTTATTGAAGTACATTTATCTAATGT
CCATGCACGCGAACCTTTCCGCCACCACTCTTATCTTTCAGATAAGGCCGTTGGTGTGATTTGCGGTTTAGGCGCAGATG
GCTACGAATTTGCTTTGAAGGCGGCAGTAAAACGTCTGCGTTCAAATTGA

Upstream 100 bases:

>100_bases
TGAGCATTCGCAAGGCAAAAATTGCAAAAGCTCATCAAATCGAATATAAAAGGTGTGCTTTTTTTACTTTAACCGTAAAA
ACAAGGAATTTAGCATCACA

Downstream 100 bases:

>100_bases
TCACTGAATATAAACAGAAGAGATTACACAATGGATATCCGTAAAATTAAGAAACTGATTGAACTAGTTGAAGAGTCTGG
CATTGCTGAACTTGAGATTT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSTQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYELIEAIHNAYQRIDFIIINPAA
FTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLSDKAVGVICGLGADGYEFALKAAVKRLRSN

Sequences:

>Translated_149_residues
MSTQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYELIEAIHNAYQRIDFIIINPAA
FTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLSDKAVGVICGLGADGYEFALKAAVKRLRSN
>Mature_148_residues
STQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYELIEAIHNAYQRIDFIIINPAAF
THTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLSDKAVGVICGLGADGYEFALKAAVKRLRSN

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_ALISL (B6ENA0)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264168.1
- GeneID:   6988221
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2834
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16577; Mature: 16446

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 103-103 BINDING 77-77 BINDING 83-83 BINDING 90-90 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYEL
CCCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEHEEEEEHHHHHCCCCHHH
IEAIHNAYQRIDFIIINPAAFTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLS
HHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCC
DKAVGVICGLGADGYEFALKAAVKRLRSN
CCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STQSRILILNGPNLNLLGLREPAHYGSQNLEQIVNALTIQATALNVELEHLQSNREYEL
CCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHEEHEEEEEHHHHHCCCCHHH
IEAIHNAYQRIDFIIINPAAFTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLS
HHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHCCC
DKAVGVICGLGADGYEFALKAAVKRLRSN
CCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA