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The map label for this gene is glmS [H]

Identifier: 209696226

GI number: 209696226

Start: 3055981

End: 3057813

Strand: Reverse

Name: glmS [H]

Synonym: VSAL_I2822

Alternate gene names: 209696226

Gene position: 3057813-3055981 (Counterclockwise)

Preceding gene: 209696227

Following gene: 209696223

Centisome position: 91.96

GC content: 44.46

Gene sequence:

>1833_bases
ATGTGTGGAATCGTAGGTGCTGTTGCACAAAGAGATGTTGCTGAAATATTAGTTGAAGGATTACGCCGTTTAGAATATCG
CGGTTATGACTCGGCTGGTGTTGCCGTTGTTGATGCAGACAGTAATTACACTCGACTGCGTCGCTTAGGTAAAGTTAAGG
AATTAGCGGATGCAGTCAATGAATCACACGTGGTCGGCGGTACTGGTATTGCTCATACTCGTTGGGCAACGCATGGTGAG
CCGTCTGAAGTGAACGCTCACCCACACGTTTCCGGTGATATTACGATTGTTCACAATGGCATTATTGAAAATCACGAATC
ATTACGTGCGCTATTAAAAGAACGCGGTTATGTATTTGAATCTCAAACGGATACCGAGGTTATTGCACACTTAGTTGAGT
GGGAATTACGAACGTCGGATTCTTTGATTGAAGCGGTACAAAAAACAGCGACTCAACTTGATGGTGCGTACGGTACTGTT
GCAATGGATCGTCGTGACCCTGAACGTTTAGTTGTCGCTCGCTCTGGTAGCCCAATCGTTATTGGTCGTGGTGTGGGTGA
AAACTTTTTAGCGTCAGATCAACTGGCGTTATTAAACGTAACTCGTCGCTTTATGTACCTTGAAGAAGGGGATGTTGCTG
AAATTACTCGTCGTGATGTTCGAGTGTTTGATGCGCATGGCGAACAAGTTGAGCGTGAAGTGACAGAATCGAACGCCGAG
CATGATGCGGGAGATAAAGGTCAATATCGTCACTTCATGCAAAAAGAAGTGTTCGAGCAGCCAAAAGCATTAATCAATAC
CATGGAAGGTCGTATTACTCATGACTCTGTTGTAACAGAAAGCATTGGCGTTAATGCTGTTGAGATCCTAAATAAAGTAG
AACACGTACAAATCATCGCATGTGGTACTTCTTACAACGCGGGAATGACGGCTCGTTATTGGTTTGAGTCACTGGCGGGT
GTTAGTTGTGATGTCGAAATTGCCTCTGAGTTCCGTTACCGTAAATTTGTAACGCGTCCAAATAGCTTATTAATTACCTT
ATCTCAATCGGGTGAAACGGCTGATACGTTAGCGGCCCTTCGTCTAGCAAAAGAGCGTGGTTACATGGGCGCAATGACGG
TGTGTAATGTTGCTGGTTCATCTCTTGTTCGTGAATCTGATTTTGCCTTTATGACGCGTGCAGGAACAGAGATTGGTGTG
GCATCGACGAAAGCCTTTACCACTCAACTTGCGGCGTTATTGATGTTAGTGACGGCGTTAGGTAAACAACAAAATCGTAT
CTCAAAAGAGAAAGAGAAAGAGATTGTTGAAGCCTTGCACGCTTTGCCCGCTCAAATAGAAAAAGCACTGTCATTTGATA
AAGAAATCGAAGCGTTAGCCCCTGACTTTGCTGACAAGCAACACACGCTATTTTTAGGGCGTGGAGAGTTTTATCCAATC
GCTATGGAAGCGTCGTTGAAATTAAAAGAGATTTCGTACATTCATGCGGAAGCGTATGCTGCCGGTGAATTAAAGCACGG
TCCTTTAGCGTTGATTGATGCGGATATGCCAGTGGTAGTGGTTGCCCCAACCAATGATTTATTAGAAAAATTAAAATCAA
ACGTAGAAGAAGTGCGTGCTCGTGGTGGGTTGCTGTATGTTTTCGCGGACGAGCAAGCGGGCTTTGAAGGCGATGAAAAC
ATGAAGATCATTACGATGCCTCATGTTAGCGATATAACTGCACCAATCTATTATACGGTTCCAATGCAGTTACTTTCGTA
TCATGTTGCCCTGATTAAAGGGACGGATGTCGATCAGCCACGTAACTTAGCAAAAGCGGTAACGGTTGAGTAA

Upstream 100 bases:

>100_bases
ATATCAATAGTGAGCTTTTTGTTGCCGCTCATTATCTAGACCAATCGCATTACCAGGATTGGGCCCACTAAATTTAAAAA
TAGAATAATGGAGTATTGCC

Downstream 100 bases:

>100_bases
GTTTTACTCATTGATAACGAAATAAAAAACGGTAGCCTCAGATAGGCTGCCGTTTTTATTTGTATATTTTAGTTATTAAG
GTTAGATCCCCGCTGGCTTA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 610; Mature: 610

Protein sequence:

>610_residues
MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGVAVVDADSNYTRLRRLGKVKELADAVNESHVVGGTGIAHTRWATHGE
PSEVNAHPHVSGDITIVHNGIIENHESLRALLKERGYVFESQTDTEVIAHLVEWELRTSDSLIEAVQKTATQLDGAYGTV
AMDRRDPERLVVARSGSPIVIGRGVGENFLASDQLALLNVTRRFMYLEEGDVAEITRRDVRVFDAHGEQVEREVTESNAE
HDAGDKGQYRHFMQKEVFEQPKALINTMEGRITHDSVVTESIGVNAVEILNKVEHVQIIACGTSYNAGMTARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKERGYMGAMTVCNVAGSSLVRESDFAFMTRAGTEIGV
ASTKAFTTQLAALLMLVTALGKQQNRISKEKEKEIVEALHALPAQIEKALSFDKEIEALAPDFADKQHTLFLGRGEFYPI
AMEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPTNDLLEKLKSNVEEVRARGGLLYVFADEQAGFEGDEN
MKIITMPHVSDITAPIYYTVPMQLLSYHVALIKGTDVDQPRNLAKAVTVE

Sequences:

>Translated_610_residues
MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGVAVVDADSNYTRLRRLGKVKELADAVNESHVVGGTGIAHTRWATHGE
PSEVNAHPHVSGDITIVHNGIIENHESLRALLKERGYVFESQTDTEVIAHLVEWELRTSDSLIEAVQKTATQLDGAYGTV
AMDRRDPERLVVARSGSPIVIGRGVGENFLASDQLALLNVTRRFMYLEEGDVAEITRRDVRVFDAHGEQVEREVTESNAE
HDAGDKGQYRHFMQKEVFEQPKALINTMEGRITHDSVVTESIGVNAVEILNKVEHVQIIACGTSYNAGMTARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKERGYMGAMTVCNVAGSSLVRESDFAFMTRAGTEIGV
ASTKAFTTQLAALLMLVTALGKQQNRISKEKEKEIVEALHALPAQIEKALSFDKEIEALAPDFADKQHTLFLGRGEFYPI
AMEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPTNDLLEKLKSNVEEVRARGGLLYVFADEQAGFEGDEN
MKIITMPHVSDITAPIYYTVPMQLLSYHVALIKGTDVDQPRNLAKAVTVE
>Mature_610_residues
MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGVAVVDADSNYTRLRRLGKVKELADAVNESHVVGGTGIAHTRWATHGE
PSEVNAHPHVSGDITIVHNGIIENHESLRALLKERGYVFESQTDTEVIAHLVEWELRTSDSLIEAVQKTATQLDGAYGTV
AMDRRDPERLVVARSGSPIVIGRGVGENFLASDQLALLNVTRRFMYLEEGDVAEITRRDVRVFDAHGEQVEREVTESNAE
HDAGDKGQYRHFMQKEVFEQPKALINTMEGRITHDSVVTESIGVNAVEILNKVEHVQIIACGTSYNAGMTARYWFESLAG
VSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAALRLAKERGYMGAMTVCNVAGSSLVRESDFAFMTRAGTEIGV
ASTKAFTTQLAALLMLVTALGKQQNRISKEKEKEIVEALHALPAQIEKALSFDKEIEALAPDFADKQHTLFLGRGEFYPI
AMEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPTNDLLEKLKSNVEEVRARGGLLYVFADEQAGFEGDEN
MKIITMPHVSDITAPIYYTVPMQLLSYHVALIKGTDVDQPRNLAKAVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=37.8654970760234, Blast_Score=420, Evalue=1e-117,
Organism=Homo sapiens, GI4826742, Length=690, Percent_Identity=36.8115942028986, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI29570798, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1790167, Length=610, Percent_Identity=72.1311475409836, Blast_Score=913, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=221, Percent_Identity=31.2217194570136, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17539970, Length=432, Percent_Identity=39.1203703703704, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17532899, Length=431, Percent_Identity=38.2830626450116, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI17532897, Length=431, Percent_Identity=38.2830626450116, Blast_Score=278, Evalue=6e-75,
Organism=Saccharomyces cerevisiae, GI6322745, Length=457, Percent_Identity=36.7614879649891, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6323731, Length=439, Percent_Identity=32.8018223234624, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323730, Length=204, Percent_Identity=36.2745098039216, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21357745, Length=694, Percent_Identity=36.3112391930836, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI28573187, Length=266, Percent_Identity=26.6917293233083, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24659598, Length=263, Percent_Identity=24.3346007604563, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 67055; Mature: 67055

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGVAVVDADSNYTRLRRLGKVKELADAVN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
ESHVVGGTGIAHTRWATHGEPSEVNAHPHVSGDITIVHNGIIENHESLRALLKERGYVFE
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEC
SQTDTEVIAHLVEWELRTSDSLIEAVQKTATQLDGAYGTVAMDRRDPERLVVARSGSPIV
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCEE
IGRGVGENFLASDQLALLNVTRRFMYLEEGDVAEITRRDVRVFDAHGEQVEREVTESNAE
EECCCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHCCEEEECCCHHHHHHHHHCCCC
HDAGDKGQYRHFMQKEVFEQPKALINTMEGRITHDSVVTESIGVNAVEILNKVEHVQIIA
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEECHHHHHHHCCCHHHHHHHHHCEEEEEE
CGTSYNAGMTARYWFESLAGVSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAAL
ECCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKERGYMGAMTVCNVAGSSLVRESDFAFMTRAGTEIGVASTKAFTTQLAALLMLVTAL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
GKQQNRISKEKEKEIVEALHALPAQIEKALSFDKEIEALAPDFADKQHTLFLGRGEFYPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCEEEE
AMEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPTNDLLEKLKSNVEEVRA
EEECCEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
RGGLLYVFADEQAGFEGDENMKIITMPHVSDITAPIYYTVPMQLLSYHVALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHEEEEECCCCCCC
RNLAKAVTVE
HHHHHHCCCC
>Mature Secondary Structure
MCGIVGAVAQRDVAEILVEGLRRLEYRGYDSAGVAVVDADSNYTRLRRLGKVKELADAVN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHC
ESHVVGGTGIAHTRWATHGEPSEVNAHPHVSGDITIVHNGIIENHESLRALLKERGYVFE
CCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEC
SQTDTEVIAHLVEWELRTSDSLIEAVQKTATQLDGAYGTVAMDRRDPERLVVARSGSPIV
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCEE
IGRGVGENFLASDQLALLNVTRRFMYLEEGDVAEITRRDVRVFDAHGEQVEREVTESNAE
EECCCCCCCCCCCCHHHHHHHHHHEEECCCCHHHHHHHCCEEEECCCHHHHHHHHHCCCC
HDAGDKGQYRHFMQKEVFEQPKALINTMEGRITHDSVVTESIGVNAVEILNKVEHVQIIA
CCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCEECHHHHHHHCCCHHHHHHHHHCEEEEEE
CGTSYNAGMTARYWFESLAGVSCDVEIASEFRYRKFVTRPNSLLITLSQSGETADTLAAL
ECCCCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHH
RLAKERGYMGAMTVCNVAGSSLVRESDFAFMTRAGTEIGVASTKAFTTQLAALLMLVTAL
HHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
GKQQNRISKEKEKEIVEALHALPAQIEKALSFDKEIEALAPDFADKQHTLFLGRGEFYPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCEEEE
AMEASLKLKEISYIHAEAYAAGELKHGPLALIDADMPVVVVAPTNDLLEKLKSNVEEVRA
EEECCEEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
RGGLLYVFADEQAGFEGDENMKIITMPHVSDITAPIYYTVPMQLLSYHVALIKGTDVDQP
CCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEHHHHHHHHHEEEEECCCCCCC
RNLAKAVTVE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA