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The map label for this gene is srlR [H]

Identifier: 209696227

GI number: 209696227

Start: 3057933

End: 3058697

Strand: Reverse

Name: srlR [H]

Synonym: VSAL_I2823

Alternate gene names: 209696227

Gene position: 3058697-3057933 (Counterclockwise)

Preceding gene: 209696230

Following gene: 209696226

Centisome position: 91.99

GC content: 39.48

Gene sequence:

>765_bases
ATGTCAAAAAGAAACACTAAACAACGTCGACATATGATCCTTTCTTTATTAATTGAGAAAGGGGAAATTACGGTTGAAGA
ACTTTCGGAGCTCTTTGATATATCAGAAGTAACCATTCGTAAGGATCTAACGGAGTTAGAGAAGAATGGTTTGCTGATGC
GTAAGTATGGCGGGGCGGTGTTAATGCCTTCAAATATCATTCAAGAAGATACGTGCGAAGAAGTTTCGAATCGAAAGTTA
TCTTTGGCTATTTCAGCGGTAGAACTGATTAAAGATCATAATCGAATCATTATTGATAGTGGCAGTACGACGGCGGCGTT
GATTAACCAATTATCAACGAAAAATGGTTTGGTTGTTATGACCAATTCATTACCGGTGGCGAATGCATTGCAAGAAATCG
AGAATGAACCCACGTTATTAATGACAGGTGGAACATGGGACAGTCATTCTGATTCATTTCAGGGTCAAGTGGCGGAGTCG
GTATTAAGATCCTATGATTTTGATCAGTTGTTCATTGGTGCAGATGGCATTGACTTAGAGCGTGGAACCACGACCTTCAA
TGAACTGGTGGGTTTAAGTCGAGTGATGTCTGAAGTCGCTCGTGAAGTAATTTTAATGGTTGAATCAGAAAAAATTGGTC
GAAAAATTCCGAATGTGGAATTGCCATGGGACAGTATTGATGTGCTGATCACCAATAATGATTTAAGCGAAGAACATCAG
AAAAAAATTGAGTCACATAACGTACGAGTCATTAGAGCTCAGTGA

Upstream 100 bases:

>100_bases
TTGTGGGATCTTAATATTTAAAACGAATTAATTCTCAACACTAGACAATCGAATGAAACGAAACTAAACTTCTTTCAAAT
CGAAACTTATTGAGTTTGTC

Downstream 100 bases:

>100_bases
TTTAATTCCTCAATAAAGAATATCAATAGTGAGCTTTTTGTTGCCGCTCATTATCTAGACCAATCGCATTACCAGGATTG
GGCCCACTAAATTTAAAAAT

Product: glucitol operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSKRNTKQRRHMILSLLIEKGEITVEELSELFDISEVTIRKDLTELEKNGLLMRKYGGAVLMPSNIIQEDTCEEVSNRKL
SLAISAVELIKDHNRIIIDSGSTTAALINQLSTKNGLVVMTNSLPVANALQEIENEPTLLMTGGTWDSHSDSFQGQVAES
VLRSYDFDQLFIGADGIDLERGTTTFNELVGLSRVMSEVAREVILMVESEKIGRKIPNVELPWDSIDVLITNNDLSEEHQ
KKIESHNVRVIRAQ

Sequences:

>Translated_254_residues
MSKRNTKQRRHMILSLLIEKGEITVEELSELFDISEVTIRKDLTELEKNGLLMRKYGGAVLMPSNIIQEDTCEEVSNRKL
SLAISAVELIKDHNRIIIDSGSTTAALINQLSTKNGLVVMTNSLPVANALQEIENEPTLLMTGGTWDSHSDSFQGQVAES
VLRSYDFDQLFIGADGIDLERGTTTFNELVGLSRVMSEVAREVILMVESEKIGRKIPNVELPWDSIDVLITNNDLSEEHQ
KKIESHNVRVIRAQ
>Mature_253_residues
SKRNTKQRRHMILSLLIEKGEITVEELSELFDISEVTIRKDLTELEKNGLLMRKYGGAVLMPSNIIQEDTCEEVSNRKLS
LAISAVELIKDHNRIIIDSGSTTAALINQLSTKNGLVVMTNSLPVANALQEIENEPTLLMTGGTWDSHSDSFQGQVAESV
LRSYDFDQLFIGADGIDLERGTTTFNELVGLSRVMSEVAREVILMVESEKIGRKIPNVELPWDSIDVLITNNDLSEEHQK
KIESHNVRVIRAQ

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=44.3548387096774, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=39.1304347826087, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI226510968, Length=251, Percent_Identity=27.8884462151394, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788069, Length=250, Percent_Identity=28.8, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789829, Length=210, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=27.9527559055118, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787540, Length=209, Percent_Identity=31.5789473684211, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87082344, Length=213, Percent_Identity=30.0469483568075, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789170, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28432; Mature: 28301

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRNTKQRRHMILSLLIEKGEITVEELSELFDISEVTIRKDLTELEKNGLLMRKYGGAV
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
LMPSNIIQEDTCEEVSNRKLSLAISAVELIKDHNRIIIDSGSTTAALINQLSTKNGLVVM
ECCCHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEE
TNSLPVANALQEIENEPTLLMTGGTWDSHSDSFQGQVAESVLRSYDFDQLFIGADGIDLE
ECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSRVMSEVAREVILMVESEKIGRKIPNVELPWDSIDVLITNNDLSEEHQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHHHH
KKIESHNVRVIRAQ
HHHHHCCEEEEEEC
>Mature Secondary Structure 
SKRNTKQRRHMILSLLIEKGEITVEELSELFDISEVTIRKDLTELEKNGLLMRKYGGAV
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
LMPSNIIQEDTCEEVSNRKLSLAISAVELIKDHNRIIIDSGSTTAALINQLSTKNGLVVM
ECCCHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCEEEE
TNSLPVANALQEIENEPTLLMTGGTWDSHSDSFQGQVAESVLRSYDFDQLFIGADGIDLE
ECCCCHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCC
RGTTTFNELVGLSRVMSEVAREVILMVESEKIGRKIPNVELPWDSIDVLITNNDLSEEHQ
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEECCCCCHHHH
KKIESHNVRVIRAQ
HHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]