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The map label for this gene is ndh [H]

Identifier: 209696225

GI number: 209696225

Start: 3054683

End: 3055912

Strand: Direct

Name: ndh [H]

Synonym: VSAL_I2821

Alternate gene names: 209696225

Gene position: 3054683-3055912 (Clockwise)

Preceding gene: 209696224

Following gene: 209696228

Centisome position: 91.87

GC content: 41.3

Gene sequence:

>1230_bases
ATGTCCCGAATCGTTGTTGTCGGTGGTGGTGCTGCTGGTTTAGAACTGTCTACCTTATTAACTAAATCTATTCGTAAAGA
AGATGACATCATTCTTGTCGAACCAGAAACGCATCATTACTGGAAACCTCGTTTGCATGAAATCGCCGCAGGCACGTTTG
ATAGTGATTTAGATTCTGTTTGTTATTTCACTCACGGCGCTCATCATGGTTATCAACACTACCAAGGCGCAATGACTGGC
ATAGATAGAGAAAATAAAACGGTATTAATTCGTCGACCTGACGGCACTGAATCAGGCATTAATTACGATTATCTTATTGT
TGCTATTGGTGCAATTAGTAATGACTTCAATACGCTTGGCGCTCAAGATCATTGCCTATTTTTAGATTCAGCAAGCCAAG
CTCGCCAAGCATGGAATCAAATTAGTCAAATACTGCGTGAAGGTAAAAACAGCACGATTAACATTGTTGGTGCAGGCGCT
ACAGGCGTTGAGCTATCAGCTGAATTGGCCAGAGTAAGTAAAAAACTAAAACGCTATAACGCCTCATCTTTAAATATTAA
TTTGATTGAAGCCGCGCATCGGGTTCTACCAAATAGCCCACAAAAAATGTCTGACAAGGTATTAAAAGAACTAGAGAAAA
GCGGTGTTAATGTATTACTTGAAACTCGTATAAGTGAAGTAACCACTAATGGAATGCGAACTAATACTGATAAATTCTTG
GGTGCAGACATTCAATTCTGGGCTGCGGGAGTTAAAGCCCCTGATTGGCTAAATGGCATTGGCGAATTAAGTTATAACCA
TATGAATCAAATTCATGTGAATCAAAACCTGAGTTCAAGCATCGATCCTCGTATCTTTGCCATTGGTGATTGTGCTGCAA
TCCCACAAGCTGACGGGTCTTTTGTTCCACCAAAAGCACAAGCAGCTAATCGTGCGGCGGTTCACCTAGCAAAAAGCTTA
GGTCGTCATTTACGTGGGAAAGAGTTAACTGATTTTACCTTCCAAGACGGTGGAATGGTCGTTGCTGTTGGTCATCACTT
TGCCGTGGGTACGTTTGCTCCTGGTACACGCTTAGAAGGCAAGTTAGTTTTGCAGGGACGATTAATTCGTCGTTTATACG
ATACTATTTTTAGACTCCATCAACGAACAGTAACGGGTATGTTTACCGTTTCTCGCTTAATGATTACTAAGCGTTCTTTA
AGCCAGCGGGGATCTAACCTTAATAACTAA

Upstream 100 bases:

>100_bases
AACAGAACGTATCCCTTTGATGTTCTGTTAGCGAATTAAATTTGGCCTTTTGCCAACGCTTTAAATTAATAGTAAAGCGT
ATATTATGTGAGTAATTCCT

Downstream 100 bases:

>100_bases
AATATACAAATAAAAACGGCAGCCTATCTGAGGCTACCGTTTTTTATTTCGTTATCAATGAGTAAAACTTACTCAACCGT
TACCGCTTTTGCTAAGTTAC

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSRIVVVGGGAAGLELSTLLTKSIRKEDDIILVEPETHHYWKPRLHEIAAGTFDSDLDSVCYFTHGAHHGYQHYQGAMTG
IDRENKTVLIRRPDGTESGINYDYLIVAIGAISNDFNTLGAQDHCLFLDSASQARQAWNQISQILREGKNSTINIVGAGA
TGVELSAELARVSKKLKRYNASSLNINLIEAAHRVLPNSPQKMSDKVLKELEKSGVNVLLETRISEVTTNGMRTNTDKFL
GADIQFWAAGVKAPDWLNGIGELSYNHMNQIHVNQNLSSSIDPRIFAIGDCAAIPQADGSFVPPKAQAANRAAVHLAKSL
GRHLRGKELTDFTFQDGGMVVAVGHHFAVGTFAPGTRLEGKLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRSL
SQRGSNLNN

Sequences:

>Translated_409_residues
MSRIVVVGGGAAGLELSTLLTKSIRKEDDIILVEPETHHYWKPRLHEIAAGTFDSDLDSVCYFTHGAHHGYQHYQGAMTG
IDRENKTVLIRRPDGTESGINYDYLIVAIGAISNDFNTLGAQDHCLFLDSASQARQAWNQISQILREGKNSTINIVGAGA
TGVELSAELARVSKKLKRYNASSLNINLIEAAHRVLPNSPQKMSDKVLKELEKSGVNVLLETRISEVTTNGMRTNTDKFL
GADIQFWAAGVKAPDWLNGIGELSYNHMNQIHVNQNLSSSIDPRIFAIGDCAAIPQADGSFVPPKAQAANRAAVHLAKSL
GRHLRGKELTDFTFQDGGMVVAVGHHFAVGTFAPGTRLEGKLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRSL
SQRGSNLNN
>Mature_408_residues
SRIVVVGGGAAGLELSTLLTKSIRKEDDIILVEPETHHYWKPRLHEIAAGTFDSDLDSVCYFTHGAHHGYQHYQGAMTGI
DRENKTVLIRRPDGTESGINYDYLIVAIGAISNDFNTLGAQDHCLFLDSASQARQAWNQISQILREGKNSTINIVGAGAT
GVELSAELARVSKKLKRYNASSLNINLIEAAHRVLPNSPQKMSDKVLKELEKSGVNVLLETRISEVTTNGMRTNTDKFLG
ADIQFWAAGVKAPDWLNGIGELSYNHMNQIHVNQNLSSSIDPRIFAIGDCAAIPQADGSFVPPKAQAANRAAVHLAKSLG
RHLRGKELTDFTFQDGGMVVAVGHHFAVGTFAPGTRLEGKLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRSLS
QRGSNLNN

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=417, Percent_Identity=38.8489208633094, Blast_Score=292, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6323794, Length=360, Percent_Identity=24.4444444444444, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323515, Length=464, Percent_Identity=23.9224137931034, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320118, Length=361, Percent_Identity=24.0997229916898, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 44892; Mature: 44760

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIVVVGGGAAGLELSTLLTKSIRKEDDIILVEPETHHYWKPRLHEIAAGTFDSDLDSV
CCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCHHHH
CYFTHGAHHGYQHYQGAMTGIDRENKTVLIRRPDGTESGINYDYLIVAIGAISNDFNTLG
EEEECCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEHHCCCCHHCC
AQDHCLFLDSASQARQAWNQISQILREGKNSTINIVGAGATGVELSAELARVSKKLKRYN
CCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
ASSLNINLIEAAHRVLPNSPQKMSDKVLKELEKSGVNVLLETRISEVTTNGMRTNTDKFL
CCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCCHHHH
GADIQFWAAGVKAPDWLNGIGELSYNHMNQIHVNQNLSSSIDPRIFAIGDCAAIPQADGS
CCCHHEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCC
FVPPKAQAANRAAVHLAKSLGRHLRGKELTDFTFQDGGMVVAVGHHFAVGTFAPGTRLEG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCEEEEECCCCCCCCC
KLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRSLSQRGSNLNN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRIVVVGGGAAGLELSTLLTKSIRKEDDIILVEPETHHYWKPRLHEIAAGTFDSDLDSV
CEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCCHHHH
CYFTHGAHHGYQHYQGAMTGIDRENKTVLIRRPDGTESGINYDYLIVAIGAISNDFNTLG
EEEECCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEEEEHHCCCCHHCC
AQDHCLFLDSASQARQAWNQISQILREGKNSTINIVGAGATGVELSAELARVSKKLKRYN
CCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCC
ASSLNINLIEAAHRVLPNSPQKMSDKVLKELEKSGVNVLLETRISEVTTNGMRTNTDKFL
CCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCCHHHH
GADIQFWAAGVKAPDWLNGIGELSYNHMNQIHVNQNLSSSIDPRIFAIGDCAAIPQADGS
CCCHHEEECCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCCC
FVPPKAQAANRAAVHLAKSLGRHLRGKELTDFTFQDGGMVVAVGHHFAVGTFAPGTRLEG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCEEEEECCCCCCCCC
KLVLQGRLIRRLYDTIFRLHQRTVTGMFTVSRLMITKRSLSQRGSNLNN
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]