Click here to switch to the map view.

The map label for this gene is frdC

Identifier: 209696196

GI number: 209696196

Start: 3023594

End: 3023977

Strand: Direct

Name: frdC

Synonym: VSAL_I2790

Alternate gene names: 209696196

Gene position: 3023594-3023977 (Clockwise)

Preceding gene: 209696195

Following gene: 209696197

Centisome position: 90.93

GC content: 41.67

Gene sequence:

>384_bases
ATGAGCAACCGTAAACCTTACGTTCGCGAAATGACACGTACGTGGTGGAAAGATCACCCTTTCTACCGTTTTTACATGGT
GCGTGAAGCAACCATTCTTCCATTGATTTTCTTTACTATCTGTCTGCTTGTTGGTTTAGGTAGTTTAGTAAAAGGTCCAC
TGGCTTGGGCTTCATGGTTAGATTTCATGGCAAACCCTATTGTGGTTGCTTTGAACATTGTTGCTTTAGCGGGTAGCTTA
TTCCATGCTCAAACTTTCTTTAGCATGATGCCGCAAGTAATGCCGATTCGTCTGGGTGGTAAAACACTAGATAAAAAAGT
GGTTGTGCTTGCACAATGGGCTGCAGTTGCAGCAATTACATTACTTGTATTGGTTATCGTTTAA

Upstream 100 bases:

>100_bases
GTCCAAAACACGTTGACCCTGCTGCGGCAGTAAACCAAGGTAAGATCGCATCATCTCAAGACTTTCTTATCGCAATGCTT
AAACCTCAGGAGGCATAAGG

Downstream 100 bases:

>100_bases
GGAGAGTTATTGTGGTAAATCTTAATCCAAAGCGTTCTGACGAACCTGTATGGTGGGGCTTATTCGGTGCTGGCGGCACT
TGGTTTGCGATGCTAACACC

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MSNRKPYVREMTRTWWKDHPFYRFYMVREATILPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSL
FHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV

Sequences:

>Translated_127_residues
MSNRKPYVREMTRTWWKDHPFYRFYMVREATILPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSL
FHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV
>Mature_126_residues
SNRKPYVREMTRTWWKDHPFYRFYMVREATILPLIFFTICLLVGLGSLVKGPLAWASWLDFMANPIVVALNIVALAGSLF
HAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAITLLVLVIV

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=125, Percent_Identity=41.6, Blast_Score=120, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_ALISL (B6EMS0)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264126.1
- GeneID:   6988560
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2790
- HOGENOM:   HBG554089
- OMA:   KMGPEPV
- ProtClustDB:   PRK04987
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 14354; Mature: 14222

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22a28ce0)-; HASH(0x228efd04)-; HASH(0x2271f9d8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRKPYVREMTRTWWKDHPFYRFYMVREATILPLIFFTICLLVGLGSLVKGPLAWASWL
CCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMANPIVVALNIVALAGSLFHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAIT
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
LLVLVIV
HHHHHHH
>Mature Secondary Structure 
SNRKPYVREMTRTWWKDHPFYRFYMVREATILPLIFFTICLLVGLGSLVKGPLAWASWL
CCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFMANPIVVALNIVALAGSLFHAQTFFSMMPQVMPIRLGGKTLDKKVVVLAQWAAVAAIT
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
LLVLVIV
HHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA