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The map label for this gene is frdD

Identifier: 209696197

GI number: 209696197

Start: 3023989

End: 3024351

Strand: Direct

Name: frdD

Synonym: VSAL_I2791

Alternate gene names: 209696197

Gene position: 3023989-3024351 (Clockwise)

Preceding gene: 209696196

Following gene: 209696199

Centisome position: 90.94

GC content: 43.25

Gene sequence:

>363_bases
GTGGTAAATCTTAATCCAAAGCGTTCTGACGAACCTGTATGGTGGGGCTTATTCGGTGCTGGCGGCACTTGGTTTGCGAT
GCTAACACCAGTAACAATCCTTGTTCTTGGTATTTTAGTACCACTTGGCGTGATCGGTCCTGAATCAATGAACTACCTAC
GTGTTGCTGGTTTTGTAACAAGCATCATTGGTGCATTATTTGTGATTGGTTCAATCTCAATGCCAATGTGGCATGCAATG
CACCGTGTACACCATGGTATGCACGATCTTAAATTCCACACAGGAACAGCAGGTAAAATCGCTTGTTATGCAACGGCAGC
ACTAGCAACCGTTCTTTCTATTGTGTTTATCTTTATGATCTAA

Upstream 100 bases:

>100_bases
GTGGTAAAACACTAGATAAAAAAGTGGTTGTGCTTGCACAATGGGCTGCAGTTGCAGCAATTACATTACTTGTATTGGTT
ATCGTTTAAGGAGAGTTATT

Downstream 100 bases:

>100_bases
TCTGAATTTAGATAAATAAAAAAAGGTTGGCTATCATGCCAACCTTTTTTGTATCTGTAATATTAAATGATATCGACTAG
ATAACAAAAAAGGCCACCGA

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor; succinate; menaquinone [C]

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVTSIIGALFVIGSISMPMWHAM
HRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI

Sequences:

>Translated_120_residues
MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVTSIIGALFVIGSISMPMWHAM
HRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI
>Mature_120_residues
MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVTSIIGALFVIGSISMPMWHAM
HRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

Organism=Escherichia coli, GI1790594, Length=115, Percent_Identity=52.1739130434783, Blast_Score=124, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_ALISL (B6EMS1)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264127.1
- GeneID:   6988561
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2791
- HOGENOM:   HBG297136
- OMA:   HRIHHGM
- ProtClustDB:   PRK05470
- HAMAP:   MF_00709
- InterPro:   IPR003418
- ProDom:   PD015693

Pfam domain/function: PF02313 Fumarate_red_D

EC number: NA

Molecular weight: Translated: 13009; Mature: 13009

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2200f8a4)-; HASH(0x22c81050)-; HASH(0x228c93d8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVT
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SIIGALFVIGSISMPMWHAMHRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MVNLNPKRSDEPVWWGLFGAGGTWFAMLTPVTILVLGILVPLGVIGPESMNYLRVAGFVT
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
SIIGALFVIGSISMPMWHAMHRVHHGMHDLKFHTGTAGKIACYATAALATVLSIVFIFMI
HHHHHHHHHHCCCCHHHHHHHHHHCCHHHCEECCCCCCHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor; fumarate; reduced menaquinone [C]

Specific reaction: succinate + acceptor = fumarate + reduced acceptor fumarate + reduced menaquinone = succinate + menaquinone [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA