Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 209696139

GI number: 209696139

Start: 2958360

End: 2959574

Strand: Direct

Name: argD [H]

Synonym: VSAL_I2733

Alternate gene names: 209696139

Gene position: 2958360-2959574 (Clockwise)

Preceding gene: 209696138

Following gene: 209696140

Centisome position: 88.97

GC content: 44.12

Gene sequence:

>1215_bases
ATGACGACCAATTCACAAGTAGAACGTAAAGACTTTAATGATGTAATGGTACCTTGTTATAACCCGATGGAAATTATTCC
AGTGAAAGGTCAAGGTGCACGAGTGTGGGATCAAGCGGGAAAAGAATACGTTGATTTTGCTGGAGGGATTGCAGTTAGTT
GTCTTGGCCACTGCCATCCAATTATGGTTAATGCACTGCAAGAGCAGTCACAAAAACTGTGGCACTTAAGTAACGTGTTA
ACGAATGAACCTGCAATTCGTCTGGCTAAAAAATTAACCGAAGTTTCTTTTGCTGAAAAAGTTTTTTTTGCTAACTCTGG
CGCAGAAGCAAATGAAGCCGCATTGAAATTGGCTCGTCGCTGGGCGGTTGATGTTCATGGTGCAGAAAAAAGTGAAATCA
TTGCATTTAAGCAAGGCTTTCATGGGCGTACTTTCTTTACCGTAACGGTCGGTGGGCAAGAAGCTTATTCTGATGGTTTT
GGACCTAAGCCGGGTGATATCTCTCATCTTGAATACAATAACCTTGCCGAACTTGAAGCGCACATGTCAGAAAAAACCTG
TGCGATCATGATGGAACCACTGCAAGGTGAAGGTGGGTTAATTTCACCAACGGCTGAATTTGTTGAGGGCGTCAGAGCGC
TATGTGACAAATACAACGCACTGCTTATTTTTGATGAAGTTCAAACCGGAAACGGCCGTACTGGTGACTTTTATGCATAC
CAAGGCTTAGGGGTTACGCCTGACATTCTGAGTACAGCTAAATCACTCGGTGGTGGCTTTCCTATTGGCGCGATGCTTAC
CACAACCGAGCTTGCTCAACATTTAAAAGTGGGTACACATGGGTCAACTTATGGTGGTAATCCATTAGCTTGTGCAGTGG
CAGAAGCCGTTGTAAACGAAGTGAGCAAGCCAGAAGTATTGGCTGGCGTGAAAGAGCGTGAACAATGGTTTCGTGACGGC
TTAGAAGCGTTGAATGCCAAATACGATATGTTTGCCGAGATACGTGGTAAAGGGTTATTGCTTGGTGCGGCATTAAATGA
AGCATGGCAAGGGCGAGCTCGTGACGTGTTAGTTGCCGCTGGTGAACAAGGCTTAATGGTCTTAGTTGCCGGTGTTAATG
TTGTTCGTTTTACGCCATCGCTAGTTATCACAAAAGAAGATGTTGAGTTAGGTTTCGAGCGTTTAGATAACGCATTAGCA
TCATTAACTAAATAA

Upstream 100 bases:

>100_bases
GTGAAACTTTTTTAGTTCAAAAAAAGAATTTTGTACTATTGAAAAGGTAATGGTTTGTAAATACTATGCTGAAAAACGGC
ATACGCAGAAGGAAAGTGTG

Downstream 100 bases:

>100_bases
TCGCCATCTCTTAATTATGTCAGTGACCCATTAATTTGGGTCACTCTTCTCAGTTCGATCTTACTTTTATTTCTACAGTA
TAGTGCTCACTCCAATGAAT

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTTNSQVERKDFNDVMVPCYNPMEIIPVKGQGARVWDQAGKEYVDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVL
TNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHGAEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGF
GPKPGDISHLEYNNLAELEAHMSEKTCAIMMEPLQGEGGLISPTAEFVEGVRALCDKYNALLIFDEVQTGNGRTGDFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAVAEAVVNEVSKPEVLAGVKEREQWFRDG
LEALNAKYDMFAEIRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGVNVVRFTPSLVITKEDVELGFERLDNALA
SLTK

Sequences:

>Translated_404_residues
MTTNSQVERKDFNDVMVPCYNPMEIIPVKGQGARVWDQAGKEYVDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVL
TNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHGAEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGF
GPKPGDISHLEYNNLAELEAHMSEKTCAIMMEPLQGEGGLISPTAEFVEGVRALCDKYNALLIFDEVQTGNGRTGDFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAVAEAVVNEVSKPEVLAGVKEREQWFRDG
LEALNAKYDMFAEIRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGVNVVRFTPSLVITKEDVELGFERLDNALA
SLTK
>Mature_403_residues
TTNSQVERKDFNDVMVPCYNPMEIIPVKGQGARVWDQAGKEYVDFAGGIAVSCLGHCHPIMVNALQEQSQKLWHLSNVLT
NEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARRWAVDVHGAEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFG
PKPGDISHLEYNNLAELEAHMSEKTCAIMMEPLQGEGGLISPTAEFVEGVRALCDKYNALLIFDEVQTGNGRTGDFYAYQ
GLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAVAEAVVNEVSKPEVLAGVKEREQWFRDGL
EALNAKYDMFAEIRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGVNVVRFTPSLVITKEDVELGFERLDNALAS
LTK

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=34.3669250645995, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=35.0993377483444, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=28.6052009456265, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=28.743961352657, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=28.9473684210526, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI24119277, Length=419, Percent_Identity=26.9689737470167, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=27.536231884058, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI188536080, Length=434, Percent_Identity=22.3502304147465, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI38679950, Length=434, Percent_Identity=22.3502304147465, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI38679946, Length=434, Percent_Identity=22.3502304147465, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=57.6441102756892, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=55.5269922879177, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1789016, Length=393, Percent_Identity=34.8600508905852, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI145693181, Length=384, Percent_Identity=34.8958333333333, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=34.0050377833753, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=32.8990228013029, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786991, Length=295, Percent_Identity=30.8474576271186, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=374, Percent_Identity=36.3636363636364, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=30.0230946882217, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=259, Percent_Identity=35.1351351351351, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=26.1282660332542, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=26.879271070615, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=34.8101265822785, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=396, Percent_Identity=35.8585858585859, Blast_Score=254, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6323470, Length=397, Percent_Identity=35.264483627204, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=335, Percent_Identity=29.5522388059701, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321456, Length=430, Percent_Identity=25.5813953488372, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=34.625322997416, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI161085790, Length=420, Percent_Identity=30.2380952380952, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574759, Length=420, Percent_Identity=29.7619047619048, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21356575, Length=423, Percent_Identity=29.3144208037825, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281366494, Length=439, Percent_Identity=23.6902050113895, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667139, Length=439, Percent_Identity=23.6902050113895, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667143, Length=439, Percent_Identity=23.6902050113895, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43612; Mature: 43481

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNSQVERKDFNDVMVPCYNPMEIIPVKGQGARVWDQAGKEYVDFAGGIAVSCLGHCHP
CCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCHHHHHHHCHHH
IMVNALQEQSQKLWHLSNVLTNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAVDVHGAEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFGPKPGDISHLEYNNLAELEA
HHEEECCCCCCCEEEEECCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCCCCCCHHHHHH
HMSEKTCAIMMEPLQGEGGLISPTAEFVEGVRALCDKYNALLIFDEVQTGNGRTGDFYAY
HHCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAVAEAVVNE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VSKPEVLAGVKEREQWFRDGLEALNAKYDMFAEIRGKGLLLGAALNEAWQGRARDVLVAA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHCCCCCEEEEEE
GEQGLMVLVAGVNVVRFTPSLVITKEDVELGFERLDNALASLTK
CCCCCEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTNSQVERKDFNDVMVPCYNPMEIIPVKGQGARVWDQAGKEYVDFAGGIAVSCLGHCHP
CCCCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHCCHHHHHHCCCHHHHHHHCHHH
IMVNALQEQSQKLWHLSNVLTNEPAIRLAKKLTEVSFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAVDVHGAEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFGPKPGDISHLEYNNLAELEA
HHEEECCCCCCCEEEEECCCCCCEEEEEEECCHHHHCCCCCCCCCCCCCCCCCCHHHHHH
HMSEKTCAIMMEPLQGEGGLISPTAEFVEGVRALCDKYNALLIFDEVQTGNGRTGDFYAY
HHCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTTELAQHLKVGTHGSTYGGNPLACAVAEAVVNE
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
VSKPEVLAGVKEREQWFRDGLEALNAKYDMFAEIRGKGLLLGAALNEAWQGRARDVLVAA
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHCCCCCEEEEEE
GEQGLMVLVAGVNVVRFTPSLVITKEDVELGFERLDNALASLTK
CCCCCEEEEECCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]