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The map label for this gene is rpe [H]

Identifier: 209696132

GI number: 209696132

Start: 2952552

End: 2953229

Strand: Direct

Name: rpe [H]

Synonym: VSAL_I2726

Alternate gene names: 209696132

Gene position: 2952552-2953229 (Clockwise)

Preceding gene: 209696131

Following gene: 209696133

Centisome position: 88.79

GC content: 41.45

Gene sequence:

>678_bases
ATGAAAGATTTTTTGATCGCACCATCTATTCTCTCTGCTGATTTTGCTCGTCTTGGTGAAGACGTAGACAAAGTATTAGC
GTCAGGCGCTGATGTGGTTCACTTTGATGTGATGGATAACCACTACGTACCAAACTTAACGTTCGGTGCGCCGATTTGTA
AAGCGTTACGTGATTACGGTATTACCGCTCCAATTGATGTGCATTTGATGGTGAAACCAGTGGACAGTATTGTTCCTGAG
TTTGCAAAAGCCGGTGCAACAATGATCACTTTCCATGTTGAAGCATCTGAACATGTTGATCGTACCCTTCAGTTAATTAA
AGAGCACGGCTGTAAAGCGGGTGTTGTTCTTAATCCTGCAACGCCATTATCCTGTCTTGACTACATTCTTGATAAAGTCG
ATATGATCTTACTTATGTCAGTTAATCCGGGTTTTGGTGGTCAGTCATTTATTCCTAGTACGTTAGATAAATTGCGTGCA
GTACGTAAATTGATCGATGACTCTGGTCGTGATATCCGTCTTGAAATTGATGGTGGCGTAAAAGTGGATAACATTCGTGA
AATCGCAGAAGCGGGCGCGGATATGTTTGTGGCAGGCTCTGCAATCTTTAATCAACCAAATTATAAAGAAGTGATAGATG
AAATGCGTGCTGAACTCGCTAAAGTGAAAGGTAATTAA

Upstream 100 bases:

>100_bases
ATTGCCTAAGACAGTGTTTAAAATATCAGGTAGAATTGCGCCGTCGATTTAATCGATTGCGTAACTCTTATCAGATACTT
ATTTTAACCTGAGGCTCAAC

Downstream 100 bases:

>100_bases
GAGACATGTTTGAAAACATCAAACTGATCGCGTTTGATTTGGATGGAACACTGCTAGATAGTGTTCCAGACTTAGCTCGT
GCGGTTGATCTTGCTATGCA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKDFLIAPSILSADFARLGEDVDKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVDMILLMSVNPGFGGQSFIPSTLDKLRA
VRKLIDDSGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN

Sequences:

>Translated_225_residues
MKDFLIAPSILSADFARLGEDVDKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVDMILLMSVNPGFGGQSFIPSTLDKLRA
VRKLIDDSGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
>Mature_225_residues
MKDFLIAPSILSADFARLGEDVDKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYGITAPIDVHLMVKPVDSIVPE
FAKAGATMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPATPLSCLDYILDKVDMILLMSVNPGFGGQSFIPSTLDKLRA
VRKLIDDSGRDIRLEIDGGVKVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=41.0377358490566, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=40.0943396226415, Blast_Score=157, Evalue=8e-39,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=7e-21,
Organism=Escherichia coli, GI1789788, Length=222, Percent_Identity=81.5315315315315, Blast_Score=372, Evalue=1e-105,
Organism=Escherichia coli, GI1790523, Length=211, Percent_Identity=36.9668246445498, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=27.0142180094787, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=216, Percent_Identity=38.4259259259259, Blast_Score=153, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=38.4279475982533, Blast_Score=161, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=40.2843601895735, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24466; Mature: 24466

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFLIAPSILSADFARLGEDVDKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC
ITAPIDVHLMVKPVDSIVPEFAKAGATMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLDYILDKVDMILLMSVNPGFGGQSFIPSTLDKLRAVRKLIDDSGRDIRLEIDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
EHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKDFLIAPSILSADFARLGEDVDKVLASGADVVHFDVMDNHYVPNLTFGAPICKALRDYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCC
ITAPIDVHLMVKPVDSIVPEFAKAGATMITFHVEASEHVDRTLQLIKEHGCKAGVVLNPA
CCCCEEEEEEECCHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCEEECCC
TPLSCLDYILDKVDMILLMSVNPGFGGQSFIPSTLDKLRAVRKLIDDSGRDIRLEIDGGV
CHHHHHHHHHHHHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVDNIREIAEAGADMFVAGSAIFNQPNYKEVIDEMRAELAKVKGN
EHHHHHHHHHCCCCEEEECHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]