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The map label for this gene is aroB

Identifier: 209696129

GI number: 209696129

Start: 2948918

End: 2950006

Strand: Direct

Name: aroB

Synonym: VSAL_I2723

Alternate gene names: 209696129

Gene position: 2948918-2950006 (Clockwise)

Preceding gene: 209696128

Following gene: 209696130

Centisome position: 88.68

GC content: 41.6

Gene sequence:

>1089_bases
ATGGAAACGATTCATGTAGATTTAGCAGAACGTAGCTATCCCATCTCTATCGGCGCCGAGTTGTTTTGCAACCCGGCGCA
TTTTTCATCTGTAATACCTGCCAAAAAACGTGTTGTCGTTATTAGTAATGTAACGGTTGCGCCGTTGTATGCTCAACAAA
TCATCGACACTTTAAATACGTTTGAATGCCAAGTATCACTGCTTGAATTAGACGATGGCGAACAATATAAAAATCTTGAT
ACTTTCAATCAAATCCTGACGTTCTTATTAGAAGAAAATCACAGCCGAGACGTGACTATTGTTGCATTAGGCGGTGGTGT
TGTTGGTGATGTGGTTGGTTTTGCCTCTGCGTGTTATCAGCGTGGTGTCGATTTTATTCAAGTTCCAACGACGTTATTGT
CCCAAGTGGATTCATCCGTTGGTGGAAAAACAGCAATAAACCATCCACTAGGTAAAAATATGGTGGGTGCCTTTTATCAA
CCTAAAGCGGTTATTATTGATATTAATTGTCTTAAGACGTTACCTGAACGCGAATTTGCAGCGGGCATGGCTGAAGTCAT
TAAATATGGCATTATTATTGATAGTGATTTCTTTGATTGGCTTGATGAGAACATGGAAAAACTCTATGCACTCGATCACG
ATGCATTGGTGTATGCCATTTCACGTTGTTGCCAAATCAAAGCGGATGTTGTGGCTAAAGATGAAAAAGAATCAGGCGTT
CGCGCACTTTTGAATTTAGGACATACTTTTGGCCATGCGATAGAGGCCGAAATGGGTTACGGTAATTGGCTTCATGGTGA
GGCCGTGTCTGCTGGAACCGTAATGGCTGCAGTGACAGCTCAAAAAGAAGGCTTAATTTCACAGCAAGAAGTGGATCGCA
TTTGTGCTCTACTTAAAAAAGCGAAATTACCTTTGAAAGCACCTAAAGAAATGACGGTAGAGGCATTTATGAAGCACATG
ATGCGTGACAAGAAAGTATTGTCAGGCAAGTTACGTTTGGTACTCCCAACTTCAATTGGTAGCTCTGAGGTCGTAACAGG
TGTTTCTGAGCGTGTTCTCGCTGATGTGATAGAGCAATGTAAGGCATAA

Upstream 100 bases:

>100_bases
CCGATGATCAAAGTGCAAAAGTGGTAGCAAATCAAATCATCCAAATGCTTGAAGAGCGTTAATTCAAGTCATTTTATAAG
ACGGATATTGGGAACGAATC

Downstream 100 bases:

>100_bases
ACGATGAATATTGGTCATGATTCAACTGTTTTAGAATTAGAAAGTCAGATTGATGTGTTATCTCGCATTCAGTTTGTTTC
TCGTTTTGGTTCTAATTTGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQVPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIIDSDFFDWLDENMEKLYALDHDALVYAISRCCQIKADVVAKDEKESGV
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQQEVDRICALLKKAKLPLKAPKEMTVEAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSERVLADVIEQCKA

Sequences:

>Translated_362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQVPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIIDSDFFDWLDENMEKLYALDHDALVYAISRCCQIKADVVAKDEKESGV
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQQEVDRICALLKKAKLPLKAPKEMTVEAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSERVLADVIEQCKA
>Mature_362_residues
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNTFECQVSLLELDDGEQYKNLD
TFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQRGVDFIQVPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQ
PKAVIIDINCLKTLPEREFAAGMAEVIKYGIIIDSDFFDWLDENMEKLYALDHDALVYAISRCCQIKADVVAKDEKESGV
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQQEVDRICALLKKAKLPLKAPKEMTVEAFMKHM
MRDKKVLSGKLRLVLPTSIGSSEVVTGVSERVLADVIEQCKA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=364, Percent_Identity=59.6153846153846, Blast_Score=447, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320332, Length=338, Percent_Identity=37.8698224852071, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_ALISL (B6EM44)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002264059.1
- GeneID:   6988264
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2723
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39534; Mature: 39534

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNT
CCEEEEECCCCCCCEEECHHHEECHHHHHHCCCCCCEEEEEECCEEHHHHHHHHHHHHCC
FECQVSLLELDDGEQYKNLDTFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQ
CEEEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RGVDFIQVPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQPKAVIIDINCLKTLPEREFA
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHCCCCHHHH
AGMAEVIKYGIIIDSDFFDWLDENMEKLYALDHDALVYAISRCCQIKADVVAKDEKESGV
HHHHHHHHHCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQQEVDRICALLKK
HHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AKLPLKAPKEMTVEAFMKHMMRDKKVLSGKLRLVLPTSIGSSEVVTGVSERVLADVIEQC
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KA
CC
>Mature Secondary Structure
METIHVDLAERSYPISIGAELFCNPAHFSSVIPAKKRVVVISNVTVAPLYAQQIIDTLNT
CCEEEEECCCCCCCEEECHHHEECHHHHHHCCCCCCEEEEEECCEEHHHHHHHHHHHHCC
FECQVSLLELDDGEQYKNLDTFNQILTFLLEENHSRDVTIVALGGGVVGDVVGFASACYQ
CEEEEEEEECCCCCHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
RGVDFIQVPTTLLSQVDSSVGGKTAINHPLGKNMVGAFYQPKAVIIDINCLKTLPEREFA
CCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCEEEEEEHHHHCCCCHHHH
AGMAEVIKYGIIIDSDFFDWLDENMEKLYALDHDALVYAISRCCQIKADVVAKDEKESGV
HHHHHHHHHCCEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
RALLNLGHTFGHAIEAEMGYGNWLHGEAVSAGTVMAAVTAQKEGLISQQEVDRICALLKK
HHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AKLPLKAPKEMTVEAFMKHMMRDKKVLSGKLRLVLPTSIGSSEVVTGVSERVLADVIEQC
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
KA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA