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The map label for this gene is exeA [H]

Identifier: 209696096

GI number: 209696096

Start: 2909780

End: 2911339

Strand: Reverse

Name: exeA [H]

Synonym: VSAL_I2688

Alternate gene names: 209696096

Gene position: 2911339-2909780 (Counterclockwise)

Preceding gene: 209696098

Following gene: 209696095

Centisome position: 87.55

GC content: 38.59

Gene sequence:

>1560_bases
ATGTACCAAGACTTCTTTGGCTTTACTGAATGTCCATTTTCAATGACTCCTAATGCGCGTTTTCTTTATTTAAGCGAGCG
TCACAAGGAGGCATTAAGCTATTTGCAATCAGGATTAGGGCAAGGGGGCGGATTTGCTTTATTAACGGGAGAAGTTGGTA
CTGGTAAAACGACAGTATCGAGAGCACTTTTTTCGGAGTTAAATGAAAATATACATCTTGCTCTTATTTTAAATCCGACA
TTTACCGCATTGGAATTATTCACGGCTATTTGTGATGAGTTAAAAATTGAATATTCATCAACACCGTCATTAAAGCAATT
AACGGAAGTGATTGTTGAGTTCTTAGTGAGTGAAGATAAAAAGGGATTTCAAACCATTGTCGCGATAGATGAAGCTCAAC
ATTTAGGTCCTGATGTATTAGAACAGCTTCGTTTATTAACTAATTTTGAAACGGACAGTGATAAATTATTAAAGGTTCTG
TTGATTGGTCAGCCTGAACTGCAACAGAAACTGCAACAAGCTAATTTACGCCAGTTGGCTCAGAGGATCACCGCTCGATA
TCATTTATTGCCGTTAACAGTAGAAGACATCCAATATTATATCGATCACCGTTTGCAGGTTGTTGGTAGTAATGCGACGT
TATTTTCGTCTTCGGCGATTAAAATCATCGCATTGCGATCAAAAGGCATTCCCCGTTTGATTAATCTATTATGCGATAAG
GCACTATGGGTGAGTTACCAACAGGGAGAAAAAAACGTTAATGCTTCATCGGTAAAGCGTGCTTGTGAATTGGTTTTAGA
GTGGGAAATCCCAGCAGTAAGTCACATTGACCTACCCGCTAAAAACAACGCGCCTTGGTTAATGTTATCTATTGCAATTG
CACTATCGGTTAGTGGTACTTGGGGGGTTTATAAAGCACTCCCTAGCTACTTAGCATCGACGTATCCTATCGTCGAACAA
GTGAAAGAACATCCATTAATCGGCTTTGATTCCGAGCAAGCGGCTTTTCAACAATTACTCGAAGTATGGGGTTATGAAAC
AAATACATTTCAAGCCAACTGTACTAATGCAAAAAGAGCGCAGTTATATTGTTTAGATAATAATGGGTCTTTAAATGATC
TATTAGCACTAAATCGCCCCGCGATTGTATGGTTACAACAAGAGAATGGAGATGACTTACTGGCTATTGTTTATCATATC
TCATCTAAAAATATTGCATTATTATTGCCAGAGCGCCAGATTGAAGTTTCTCATCAATGGTTTGAAAAACATTGGAATGG
CGCTTATATGCAACTCTGGAAAAAACCAATTATGACCAAAAGAGCGATGAGACTTGGTGATGAAGGTGAAGCCATTGTGG
AATTGAATCAATTACTTTCTTTTGCCTTAGAGCAACCACTGACTGATTCGAATCGTTTTACTGAAGAAACCGAAGAACAA
GTTAAGCAATTTCAAGCTATTTTCGGTTTGAAGACAGATGGAGTGGTGGGGTCAAGTACGTTAATGTGGTTAGACAGTGT
GATAAATACCAATGTCCCTATGCTTCAAGGAGACAAATAA

Upstream 100 bases:

>100_bases
TACTTTCTGACTTCCAATGATACCGTGCAATGATAATATTTCGACTTTTTATTCGAAGACTCACTCATCGATATAGATAA
ATTAGGTAGATCCCCCTTTT

Downstream 100 bases:

>100_bases
ATGAGTACTTTCTTTTCTCATCCTTCAAAGTTTTTGATAGGTTCATTGGTGATATTACCTCCCTTTGCTTTATCCTTGGT
TATCGCGTTGCCTTATTATG

Product: general secretion pathway protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MYQDFFGFTECPFSMTPNARFLYLSERHKEALSYLQSGLGQGGGFALLTGEVGTGKTTVSRALFSELNENIHLALILNPT
FTALELFTAICDELKIEYSSTPSLKQLTEVIVEFLVSEDKKGFQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQANLRQLAQRITARYHLLPLTVEDIQYYIDHRLQVVGSNATLFSSSAIKIIALRSKGIPRLINLLCDK
ALWVSYQQGEKNVNASSVKRACELVLEWEIPAVSHIDLPAKNNAPWLMLSIAIALSVSGTWGVYKALPSYLASTYPIVEQ
VKEHPLIGFDSEQAAFQQLLEVWGYETNTFQANCTNAKRAQLYCLDNNGSLNDLLALNRPAIVWLQQENGDDLLAIVYHI
SSKNIALLLPERQIEVSHQWFEKHWNGAYMQLWKKPIMTKRAMRLGDEGEAIVELNQLLSFALEQPLTDSNRFTEETEEQ
VKQFQAIFGLKTDGVVGSSTLMWLDSVINTNVPMLQGDK

Sequences:

>Translated_519_residues
MYQDFFGFTECPFSMTPNARFLYLSERHKEALSYLQSGLGQGGGFALLTGEVGTGKTTVSRALFSELNENIHLALILNPT
FTALELFTAICDELKIEYSSTPSLKQLTEVIVEFLVSEDKKGFQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQANLRQLAQRITARYHLLPLTVEDIQYYIDHRLQVVGSNATLFSSSAIKIIALRSKGIPRLINLLCDK
ALWVSYQQGEKNVNASSVKRACELVLEWEIPAVSHIDLPAKNNAPWLMLSIAIALSVSGTWGVYKALPSYLASTYPIVEQ
VKEHPLIGFDSEQAAFQQLLEVWGYETNTFQANCTNAKRAQLYCLDNNGSLNDLLALNRPAIVWLQQENGDDLLAIVYHI
SSKNIALLLPERQIEVSHQWFEKHWNGAYMQLWKKPIMTKRAMRLGDEGEAIVELNQLLSFALEQPLTDSNRFTEETEEQ
VKQFQAIFGLKTDGVVGSSTLMWLDSVINTNVPMLQGDK
>Mature_519_residues
MYQDFFGFTECPFSMTPNARFLYLSERHKEALSYLQSGLGQGGGFALLTGEVGTGKTTVSRALFSELNENIHLALILNPT
FTALELFTAICDELKIEYSSTPSLKQLTEVIVEFLVSEDKKGFQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVL
LIGQPELQQKLQQANLRQLAQRITARYHLLPLTVEDIQYYIDHRLQVVGSNATLFSSSAIKIIALRSKGIPRLINLLCDK
ALWVSYQQGEKNVNASSVKRACELVLEWEIPAVSHIDLPAKNNAPWLMLSIAIALSVSGTWGVYKALPSYLASTYPIVEQ
VKEHPLIGFDSEQAAFQQLLEVWGYETNTFQANCTNAKRAQLYCLDNNGSLNDLLALNRPAIVWLQQENGDDLLAIVYHI
SSKNIALLLPERQIEVSHQWFEKHWNGAYMQLWKKPIMTKRAMRLGDEGEAIVELNQLLSFALEQPLTDSNRFTEETEEQ
VKQFQAIFGLKTDGVVGSSTLMWLDSVINTNVPMLQGDK

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=489, Percent_Identity=26.7893660531697, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 58385; Mature: 58385

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQDFFGFTECPFSMTPNARFLYLSERHKEALSYLQSGLGQGGGFALLTGEVGTGKTTVS
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RALFSELNENIHLALILNPTFTALELFTAICDELKIEYSSTPSLKQLTEVIVEFLVSEDK
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCC
KGFQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVLLIGQPELQQKLQQANLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHH
QRITARYHLLPLTVEDIQYYIDHRLQVVGSNATLFSSSAIKIIALRSKGIPRLINLLCDK
HHHHHHHEEEEEEHHHHHHHHHCEEEEEECCCEEECCCCEEEEEECCCCHHHHHHHHHHH
ALWVSYQQGEKNVNASSVKRACELVLEWEIPAVSHIDLPAKNNAPWLMLSIAIALSVSGT
HHEEEECCCCCCCCHHHHHHHHHHEEEECCCCEEEECCCCCCCCCEEEEEEEEHHCCCCC
WGVYKALPSYLASTYPIVEQVKEHPLIGFDSEQAAFQQLLEVWGYETNTFQANCTNAKRA
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEE
QLYCLDNNGSLNDLLALNRPAIVWLQQENGDDLLAIVYHISSKNIALLLPERQIEVSHQW
EEEEECCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEECCCHHHHHHHH
FEKHWNGAYMQLWKKPIMTKRAMRLGDEGEAIVELNQLLSFALEQPLTDSNRFTEETEEQ
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VKQFQAIFGLKTDGVVGSSTLMWLDSVINTNVPMLQGDK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEECCC
>Mature Secondary Structure
MYQDFFGFTECPFSMTPNARFLYLSERHKEALSYLQSGLGQGGGFALLTGEVGTGKTTVS
CCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHH
RALFSELNENIHLALILNPTFTALELFTAICDELKIEYSSTPSLKQLTEVIVEFLVSEDK
HHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCCC
KGFQTIVAIDEAQHLGPDVLEQLRLLTNFETDSDKLLKVLLIGQPELQQKLQQANLRQLA
CCCEEEEEECCHHHCCHHHHHHHHHHHCCCCCHHHHEEEEECCCHHHHHHHHHHHHHHHH
QRITARYHLLPLTVEDIQYYIDHRLQVVGSNATLFSSSAIKIIALRSKGIPRLINLLCDK
HHHHHHHEEEEEEHHHHHHHHHCEEEEEECCCEEECCCCEEEEEECCCCHHHHHHHHHHH
ALWVSYQQGEKNVNASSVKRACELVLEWEIPAVSHIDLPAKNNAPWLMLSIAIALSVSGT
HHEEEECCCCCCCCHHHHHHHHHHEEEECCCCEEEECCCCCCCCCEEEEEEEEHHCCCCC
WGVYKALPSYLASTYPIVEQVKEHPLIGFDSEQAAFQQLLEVWGYETNTFQANCTNAKRA
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCEE
QLYCLDNNGSLNDLLALNRPAIVWLQQENGDDLLAIVYHISSKNIALLLPERQIEVSHQW
EEEEECCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEECCCHHHHHHHH
FEKHWNGAYMQLWKKPIMTKRAMRLGDEGEAIVELNQLLSFALEQPLTDSNRFTEETEEQ
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
VKQFQAIFGLKTDGVVGSSTLMWLDSVINTNVPMLQGDK
HHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]