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The map label for this gene is degQ [H]

Identifier: 209696075

GI number: 209696075

Start: 2883961

End: 2885328

Strand: Direct

Name: degQ [H]

Synonym: VSAL_I2667

Alternate gene names: 209696075

Gene position: 2883961-2885328 (Clockwise)

Preceding gene: 209696074

Following gene: 209696076

Centisome position: 86.73

GC content: 42.11

Gene sequence:

>1368_bases
ATGAAGAAACCTTTATTAATTTTAGGCTTACTGACGTTAACGATCAGTACCATCATCACCCCAATTCAAACTCAAGCTGC
CCTTCCTCTTACTGTCAATTCTCAGCAGCTGCCAAGTTTGGCTCCGATGCTCGAAAAAATAACCCCCGCAGTGGTTAGTA
TTTCTGTCGAAGGGACTCAACTATCAAAACGTCAGATCCCTGAACAATTTCGTTTCTTTTTAGGTCCAGACTTCCCAGAA
GAGCAAGCTCAAGAGCGCCCATTCAAAGGGTTAGGCTCTGGCGTTATACTTGATGCCCAAAAAGGCTATATCGTTACCAA
TCATCACGTCATTAATAATGCCAAAGAAATCCTCGTTCAGTTGCATGATGGCCGAGAATATAAAGCAGAACTCATTGGCA
GTGACGAAATGTCAGACATTGCCTTATTAAAATTAGAGGAAGCTAAAGACTTAACACAGATAGTGCTTTCTGATTCAGAT
GATTTACGCGTGGGAGATTTCAGTGTTGCTATCGGTAATCCTTTTGGTTTAGGGCAAACCGTCACCTCGGGTATCGTCTC
AGCCTTAGGACGCAGCGGACTAAATCTTGAAAATTTTGAAAACTTCATCCAAACCGATGCAGCAATTAATAGCGGTAACT
CTGGCGGGGCATTAGTCAATCTTAATGGTGAGCTGATTGGGATAAATACCGCAATTTTAGGTCCGAATGGCGGTAATGTC
GGTATTGGTTTTGCCATCCCATCGAACATGGTTCGAAACTTATCTGAGCAAATTATTGAGTTTGGTCACGTCAAGCGAGG
GATCCTTGGTGTTCAAGGTGGAGAACTCACCGCTGAGCTTGCTGAAGCATTCGATTATGACACTAATCACGGTGCATTTG
TCAGCCAAGTATTACCCGATGGCGCTGCCGAAAAAGCGGGAATAAAAGCAGGCGATATTTTAATTTCCCTGAATGGAAAA
AACATTCAAAGTTTTGGGGAACTGAGAGCCAAAGTAGCCACACTTGGCGCAGGTAAAAAAATCACTTTAGGGTTAATCCG
TGATGGCAAAGAGAAAACCGTTATTGCTACTCTCGCAGAAGCCGACCAAATAAAAACAAAAGCAGAAAACCTACATGAAG
GACTAAAAGGCGCTCAATTAAAAAATACTGCATCGTCAGATCCGATAAAGGGTGTAAAAGTCAGTGCAATACAAAAAAGG
TCAATGGCACAACGTTATGGCTTACAGAAAGACGATATTATTATTGGCGTCAATCGAACTCAGATTAAGAACTTGCAACA
ATTTAGACAATTACTCGACAGCAAACCGCCCGTTTTAGCTCTCAACATTCAACGTGGGAAGCAAACCTTATATCTTGTTA
TTCGTTAA

Upstream 100 bases:

>100_bases
AAGAAGATAAAATTGCATAATAAATAAACACCACAATGAACTTTTTTAAAGGTTTCTAAGTCTCACATATACATCTTTAT
TATAAATGGAGTATATGTAG

Downstream 100 bases:

>100_bases
TAGGTAGAATATAAAAAGTAGGCTCTATTCTTCATTTCGATGAGCCGAGCCTGCTCTTTCTTCTCTACTTCTTGGCAACA
TTAATGTTATCCTAACTTCT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKKPLLILGLLTLTISTIITPIQTQAALPLTVNSQQLPSLAPMLEKITPAVVSISVEGTQLSKRQIPEQFRFFLGPDFPE
EQAQERPFKGLGSGVILDAQKGYIVTNHHVINNAKEILVQLHDGREYKAELIGSDEMSDIALLKLEEAKDLTQIVLSDSD
DLRVGDFSVAIGNPFGLGQTVTSGIVSALGRSGLNLENFENFIQTDAAINSGNSGGALVNLNGELIGINTAILGPNGGNV
GIGFAIPSNMVRNLSEQIIEFGHVKRGILGVQGGELTAELAEAFDYDTNHGAFVSQVLPDGAAEKAGIKAGDILISLNGK
NIQSFGELRAKVATLGAGKKITLGLIRDGKEKTVIATLAEADQIKTKAENLHEGLKGAQLKNTASSDPIKGVKVSAIQKR
SMAQRYGLQKDDIIIGVNRTQIKNLQQFRQLLDSKPPVLALNIQRGKQTLYLVIR

Sequences:

>Translated_455_residues
MKKPLLILGLLTLTISTIITPIQTQAALPLTVNSQQLPSLAPMLEKITPAVVSISVEGTQLSKRQIPEQFRFFLGPDFPE
EQAQERPFKGLGSGVILDAQKGYIVTNHHVINNAKEILVQLHDGREYKAELIGSDEMSDIALLKLEEAKDLTQIVLSDSD
DLRVGDFSVAIGNPFGLGQTVTSGIVSALGRSGLNLENFENFIQTDAAINSGNSGGALVNLNGELIGINTAILGPNGGNV
GIGFAIPSNMVRNLSEQIIEFGHVKRGILGVQGGELTAELAEAFDYDTNHGAFVSQVLPDGAAEKAGIKAGDILISLNGK
NIQSFGELRAKVATLGAGKKITLGLIRDGKEKTVIATLAEADQIKTKAENLHEGLKGAQLKNTASSDPIKGVKVSAIQKR
SMAQRYGLQKDDIIIGVNRTQIKNLQQFRQLLDSKPPVLALNIQRGKQTLYLVIR
>Mature_455_residues
MKKPLLILGLLTLTISTIITPIQTQAALPLTVNSQQLPSLAPMLEKITPAVVSISVEGTQLSKRQIPEQFRFFLGPDFPE
EQAQERPFKGLGSGVILDAQKGYIVTNHHVINNAKEILVQLHDGREYKAELIGSDEMSDIALLKLEEAKDLTQIVLSDSD
DLRVGDFSVAIGNPFGLGQTVTSGIVSALGRSGLNLENFENFIQTDAAINSGNSGGALVNLNGELIGINTAILGPNGGNV
GIGFAIPSNMVRNLSEQIIEFGHVKRGILGVQGGELTAELAEAFDYDTNHGAFVSQVLPDGAAEKAGIKAGDILISLNGK
NIQSFGELRAKVATLGAGKKITLGLIRDGKEKTVIATLAEADQIKTKAENLHEGLKGAQLKNTASSDPIKGVKVSAIQKR
SMAQRYGLQKDDIIIGVNRTQIKNLQQFRQLLDSKPPVLALNIQRGKQTLYLVIR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=337, Percent_Identity=36.4985163204748, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI22129776, Length=339, Percent_Identity=35.693215339233, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI24308541, Length=317, Percent_Identity=34.0694006309148, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI7019477, Length=315, Percent_Identity=34.6031746031746, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789629, Length=457, Percent_Identity=56.6739606126915, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1786356, Length=453, Percent_Identity=55.6291390728477, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1789630, Length=276, Percent_Identity=45.2898550724638, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24646839, Length=336, Percent_Identity=31.25, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 48714; Mature: 48714

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPLLILGLLTLTISTIITPIQTQAALPLTVNSQQLPSLAPMLEKITPAVVSISVEGTQ
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHCCHHHHHHHHCCCEEEEEEECCCC
LSKRQIPEQFRFFLGPDFPEEQAQERPFKGLGSGVILDAQKGYIVTNHHVINNAKEILVQ
CHHHHCCHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEECCCCEEEECCHHHCCHHHEEEE
LHDGREYKAELIGSDEMSDIALLKLEEAKDLTQIVLSDSDDLRVGDFSVAIGNPFGLGQT
ECCCCCEEHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEECEEEEEECCCCCCCHH
VTSGIVSALGRSGLNLENFENFIQTDAAINSGNSGGALVNLNGELIGINTAILGPNGGNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEECCCCCCE
GIGFAIPSNMVRNLSEQIIEFGHVKRGILGVQGGELTAELAEAFDYDTNHGAFVSQVLPD
EEEEECCHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHCCC
GAAEKAGIKAGDILISLNGKNIQSFGELRAKVATLGAGKKITLGLIRDGKEKTVIATLAE
CCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHH
ADQIKTKAENLHEGLKGAQLKNTASSDPIKGVKVSAIQKRSMAQRYGLQKDDIIIGVNRT
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCHH
QIKNLQQFRQLLDSKPPVLALNIQRGKQTLYLVIR
HHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEC
>Mature Secondary Structure
MKKPLLILGLLTLTISTIITPIQTQAALPLTVNSQQLPSLAPMLEKITPAVVSISVEGTQ
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECHHHCCHHHHHHHHCCCEEEEEEECCCC
LSKRQIPEQFRFFLGPDFPEEQAQERPFKGLGSGVILDAQKGYIVTNHHVINNAKEILVQ
CHHHHCCHHHHHHCCCCCCHHHHHCCCCCCCCCCEEEECCCCEEEECCHHHCCHHHEEEE
LHDGREYKAELIGSDEMSDIALLKLEEAKDLTQIVLSDSDDLRVGDFSVAIGNPFGLGQT
ECCCCCEEHHCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEECEEEEEECCCCCCCHH
VTSGIVSALGRSGLNLENFENFIQTDAAINSGNSGGALVNLNGELIGINTAILGPNGGNV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEEEEECCCCCCE
GIGFAIPSNMVRNLSEQIIEFGHVKRGILGVQGGELTAELAEAFDYDTNHGAFVSQVLPD
EEEEECCHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHCCCCCCCHHHHHHCCC
GAAEKAGIKAGDILISLNGKNIQSFGELRAKVATLGAGKKITLGLIRDGKEKTVIATLAE
CCCHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEHH
ADQIKTKAENLHEGLKGAQLKNTASSDPIKGVKVSAIQKRSMAQRYGLQKDDIIIGVNRT
HHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCHH
QIKNLQQFRQLLDSKPPVLALNIQRGKQTLYLVIR
HHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]