Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 209696055

GI number: 209696055

Start: 2864846

End: 2865928

Strand: Reverse

Name: mraY

Synonym: VSAL_I2647

Alternate gene names: 209696055

Gene position: 2865928-2864846 (Counterclockwise)

Preceding gene: 209696056

Following gene: 209696054

Centisome position: 86.19

GC content: 40.54

Gene sequence:

>1083_bases
ATGATTATCTGGTTATCTAACTTTCTAGAGCAATATTTCCCATTTTTTCGTTTATTCGAATACCTTAGCTTTCGAGCTAT
TTTAAGTATTATTACCGCATTATCTATTTCGTTATGGATGGGGCCTAAACTGATTCGATGGTTACAAAATCTTCAAATCG
GTCAAGTAGTACGTGATGATGGTCCTGAATCTCATTTCAGTAAGCGCGGTACGCCAACCATGGGCGGTATCATGATATTA
ACGGCTATTACGGTCACTGTCTTCTTATGGGCAGATCTTACAAATCCTTATGTTTGGGCGGTCATGTTTGTATTGCTAGG
CTATGGTGCCGTTGGTTTTGTTGATGACTATCGTAAAGTGGTTCGTAAAAATACGGACGGTTTGATTGCTCGTTGGAAGT
ACTTCTGGCAATCAGCCATTGCATTAGTGGTTGCGTTTGCTTTATATGCTTATGGTAAAGATACGGCGGCAACACAGCTC
GTTGTTCCTTTCTTTAAAGATATAATGCCACAACTTGGTTTAACTTATATTTTGCTAACCTACTTTGTTATTGTCGGTAC
AAGTAATGCAGTAAACCTAACGGATGGATTGGATGGTTTAGCTATCATGCCAACGGTATTTGTTGCCGCTGGTTTTGCTT
TTATTGCATGGGCGACAGGCAACGTACAATTTGCGAATTACTTACATATTCCACATATTCCACAAGCAAGTGAGTTGGTT
GTTGTCTGCGCTGCGATTGTCGGTGCTGGATTTGGTTTCTTATGGTTTAACACTTACCCTGCACAAGTATTTATGGGCGA
TGTTGGTTCATTAGCACTGGGTGGCGCACTAGGTACGATAGCGGTTTTAGTACGTCAAGAATTCCTTTTGGTTATCATGG
GTGGTGTATTTGTTGTAGAAACACTTTCTGTAATTCTACAAGTTGGCTCATACAAGCTACGTGGTCAACGTATCTTCCGT
ATGGCTCCAATTCATCACCATTATGAATTGAAAGGGTGGCCAGAACCGCGTGTAATCGTGCGTTTTTGGATTATCTCTAT
GTTATTGGTTCTTATTGCATTAGCGACATTGAAGGTACGTTAA

Upstream 100 bases:

>100_bases
AATTACAATTAATTAAACATAATGAGGTTACCGTGCTAGTAAAAGGTGCCAATAGTTCACGTATGAGCGAAGTAGTTTTA
GCTCTTAAGGAGTGTCAGTA

Downstream 100 bases:

>100_bases
TATGACTGGTTTTGGTGGTGTAAAAAACGTTGTTGTGGTTGGCTTAGGAATGACAGGGTTATCTGTTGTTAAGCATTTGC
TGAGACAACCAGAAGCGTTA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALSISLWMGPKLIRWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDIMPQLGLTYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPQASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR

Sequences:

>Translated_360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALSISLWMGPKLIRWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDIMPQLGLTYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPQASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
>Mature_360_residues
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALSISLWMGPKLIRWLQNLQIGQVVRDDGPESHFSKRGTPTMGGIMIL
TAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQL
VVPFFKDIMPQLGLTYILLTYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPQASELV
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=80.2777777777778, Blast_Score=576, Evalue=1e-166,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_ALISL (B6ELH8)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263985.1
- GeneID:   6988861
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I2647
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40208; Mature: 40208

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x223b84dc)-; HASH(0x22a2e744)-; HASH(0x22973c64)-; HASH(0x22a2f5c4)-; HASH(0x22a3b754)-; HASH(0x22a2aa10)-; HASH(0x22a34d10)-; HASH(0x22a2a908)-; HASH(0x22a323ac)-; HASH(0x22a2f6b4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALSISLWMGPKLIRWLQNLQIGQVVRDD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCC
GPESHFSKRGTPTMGGIMILTAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQLVVPFFKDIMPQLGLTYILLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPQASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCCCHHHHH
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVE
HHHHHHHHCCCHHHHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIIWLSNFLEQYFPFFRLFEYLSFRAILSIITALSISLWMGPKLIRWLQNLQIGQVVRDD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHCC
GPESHFSKRGTPTMGGIMILTAITVTVFLWADLTNPYVWAVMFVLLGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAYGKDTAATQLVVPFFKDIMPQLGLTYILLT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFAFIAWATGNVQFANYLHIPHIPQASELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCCEEEEEEECCCCCCCHHHHH
VVCAAIVGAGFGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLVRQEFLLVIMGGVFVVE
HHHHHHHHCCCHHHHEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMLLVLIALATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA