Click here to switch to the map view.

The map label for this gene is can [H]

Identifier: 209696028

GI number: 209696028

Start: 2830820

End: 2831479

Strand: Direct

Name: can [H]

Synonym: VSAL_I2616

Alternate gene names: 209696028

Gene position: 2830820-2831479 (Clockwise)

Preceding gene: 209696023

Following gene: 209696031

Centisome position: 85.13

GC content: 37.27

Gene sequence:

>660_bases
ATGCCAGAATTAAAAGAACTCTTTGCCAATAACAGTAAATGGTCTAAAAAAATCAAATCTGAAAATCCAGAATTCTTCAT
TCAGTTAGAAGAAGGACAAAATCCAGATTATTTATGGATTGGCTGCTCTGACAGTCGAGTACCGGCAGAACGCCTAACCG
GATTACATTCAGGTGAGCTTTTTGTACACCGTAATGTAGCGAACCAAGTTATTCATACAGATTTAAATTGCTTATCTGTA
CTCCAATATGCGGTCGATGTATTGAAAGTCAAACATATAATTGTTTGCGGCCACTATGGTTGTGGCGGTGTAAATGCCGC
AATTGATAACCCTCAATTAGGTTTAATCAATAATTGGCTACTACATATCAGAGACTTATATTTAAAACATCGTACTTTAT
TTGGCTTCCTTCCTCGTGAAGAATGGGGTGATAAATTATGTGAAATAAATGTAGCGGAACAAGTTTATAACGTAGGTAAT
TCTACCATTATGCAAAATGCATGGGAACGAGGCCAAGAAGTTCATGTTCATGGTGTCGTTTATGGTATGGGAGATGGTGT
TTTAAATGATCTTGGTGTCAAAGGGCACAGCAGAGAATCCTTAGAAATATCTTACCAAGCCGCAATGGCTATTATAACGA
ACCCTGTAAGTAAAGCATAA

Upstream 100 bases:

>100_bases
TCATATTTTGTTATCTTCTTATTGAAATATTTACAACAAATCGGATTTGATAAATCAAAAGCTTGTGTATAGTAAAGCAG
GATAAATAGAAGGACTTACC

Downstream 100 bases:

>100_bases
ATCAAAAAAGAGCAGATAATCTGCTCTTTTTTAAGATTTACTCAATGTTATTGCTAAATAAACCAGAAGGATATTTCCTT
CTGGTTATCACTACGTTGTA

Product: carbonic anhydrase 2

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPELKELFANNSKWSKKIKSENPEFFIQLEEGQNPDYLWIGCSDSRVPAERLTGLHSGELFVHRNVANQVIHTDLNCLSV
LQYAVDVLKVKHIIVCGHYGCGGVNAAIDNPQLGLINNWLLHIRDLYLKHRTLFGFLPREEWGDKLCEINVAEQVYNVGN
STIMQNAWERGQEVHVHGVVYGMGDGVLNDLGVKGHSRESLEISYQAAMAIITNPVSKA

Sequences:

>Translated_219_residues
MPELKELFANNSKWSKKIKSENPEFFIQLEEGQNPDYLWIGCSDSRVPAERLTGLHSGELFVHRNVANQVIHTDLNCLSV
LQYAVDVLKVKHIIVCGHYGCGGVNAAIDNPQLGLINNWLLHIRDLYLKHRTLFGFLPREEWGDKLCEINVAEQVYNVGN
STIMQNAWERGQEVHVHGVVYGMGDGVLNDLGVKGHSRESLEISYQAAMAIITNPVSKA
>Mature_218_residues
PELKELFANNSKWSKKIKSENPEFFIQLEEGQNPDYLWIGCSDSRVPAERLTGLHSGELFVHRNVANQVIHTDLNCLSVL
QYAVDVLKVKHIIVCGHYGCGGVNAAIDNPQLGLINNWLLHIRDLYLKHRTLFGFLPREEWGDKLCEINVAEQVYNVGNS
TIMQNAWERGQEVHVHGVVYGMGDGVLNDLGVKGHSRESLEISYQAAMAIITNPVSKA

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=210, Percent_Identity=64.2857142857143, Blast_Score=293, Evalue=5e-81,
Organism=Escherichia coli, GI1786534, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324292, Length=199, Percent_Identity=31.1557788944724, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 24577; Mature: 24446

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELKELFANNSKWSKKIKSENPEFFIQLEEGQNPDYLWIGCSDSRVPAERLTGLHSGEL
CCCHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANQVIHTDLNCLSVLQYAVDVLKVKHIIVCGHYGCGGVNAAIDNPQLGLINNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHH
LHIRDLYLKHRTLFGFLPREEWGDKLCEINVAEQVYNVGNSTIMQNAWERGQEVHVHGVV
HHHHHHHHHHHHHHCCCCCHHHCCHHEEEEHHHHHHHCCCHHHHHHHHHCCCEEEEEEEE
YGMGDGVLNDLGVKGHSRESLEISYQAAMAIITNPVSKA
EECCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PELKELFANNSKWSKKIKSENPEFFIQLEEGQNPDYLWIGCSDSRVPAERLTGLHSGEL
CCHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHCCCCCCCE
FVHRNVANQVIHTDLNCLSVLQYAVDVLKVKHIIVCGHYGCGGVNAAIDNPQLGLINNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHH
LHIRDLYLKHRTLFGFLPREEWGDKLCEINVAEQVYNVGNSTIMQNAWERGQEVHVHGVV
HHHHHHHHHHHHHHCCCCCHHHCCHHEEEEHHHHHHHCCCHHHHHHHHHCCCEEEEEEEE
YGMGDGVLNDLGVKGHSRESLEISYQAAMAIITNPVSKA
EECCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]