| Definition | Aliivibrio salmonicida LFI1238 chromosome 1, complete genome. |
|---|---|
| Accession | NC_011312 |
| Length | 3,325,165 |
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The map label for this gene is thrA [H]
Identifier: 209695974
GI number: 209695974
Start: 2736372
End: 2738831
Strand: Reverse
Name: thrA [H]
Synonym: VSAL_I2556
Alternate gene names: 209695974
Gene position: 2738831-2736372 (Counterclockwise)
Preceding gene: 209695975
Following gene: 209695973
Centisome position: 82.37
GC content: 40.2
Gene sequence:
>2460_bases ATGCGAGTATTAAAGTTTGGTGGTTCGTCATTAGCAGATTCAGATCGTTTTTTACGTGCCGCAGATATCATTGCCAATAA TGCGCAACAGCAAGATGTTTCTGTTGTTTTATCGGCACCGGGTAAGGTAACGAATAAGTTAGTTTCAGTCGTTGATAACG TATTAACGAATGGAGAAGCTGAGTTACAAATTTCAGAATTAGAAGCTGTTTTTATTCAGTTGTTTGATGGTATTTCTACC GCACTTCCACAAGTCGATCTTAAAACGCTTGAAAATAAGCTAAAAGATTCACTTTCTCAACTTCGCCAATATGTGCATGG TATTAGTTTATTAGGTATGTGCCCTGATAATGTCTATGCAAAAATCATCAGTAAAGGCGAACGTATTTCAGTCGTTACAA TGAAGGCGGTACTTGAAGCTAAAGGGCAACAAGCAAGCCTTATCGACCCAGTTAAATATCTTTATGCTCGTGGTAGTTTT TTAGAAGGTGCTGTTGATGTTGATATTTCGACGCTGAATTTTAAAAATGAACCTCTTCCTAAAGGGCACGTAAATATCAT GCCTGGTTTTACTGCAGGGAATGAAAAAGGTGAATTGCTTACTTTAGGGCGTAACGGATCTGATTATTCAGCGGCGGTGC TTGCCGCTTGTCTTCGTGCCGAGTGTTGTGAGATTTGGACTGATGTTGATGGTGTTTATAACTGTGACCCTCGATTAGTT GATGATGCTCGTCTACTTAAGTCTTTAAGCTATCAAGAAGCAATGGAATTGTCGTATTTTGGGGCTTCAGTTTTGCATCC TAAAACCATCGCACCTATTGCTCAATTTCATATTCCTTGCCTAATTAAAAACAGTTTTAACCCTCAAGGTCCAGGCACGC TTATTGGCCAAGATACAGGTGAAGATAATTTAGCCATTAAAGGGATAACGACATTAAGTAATTTAACGATGGTTAACGTC AGTGGCCCTGGCATGAAAGGCATGGTTGGTATGGCAAGCCGTGTATTTGGTGCAATGTCTACGGCTGGTATTTCTATTGT CTTAATTACTCAGTCTTCTTCTGAGTACAGTATCAGCTTTTGTATTGAGGCTGAGGATAAAGTACAAGCAGAGCAAGTAT TACGCGAAGCGTTTGAATTAGAATTAAAAGACGGTTTATTAGAACCCGTTGAATTTATTAATGATGTTGCTATCGTAACG CTAGTTGGTGATGGCATGAGAACATCAAAAGGTGTGGCTTCTCAATTCTTTACATCATTAACAGAAGTGAACGTTAATAT CATTGCTATTGCTCAAGGCTCTTCTGAGCGAGCTATTTCAGCCGTCATTCCTGAAGATAAAGTGTCTGAATCAATTAAAG CGTGTCACGAGAATCTCTTCAATAGTAAGCATTTCTTAGATGTTTTTGTCGTAGGTGTTGGTGGTGTTGGTGGTGAGTTA GTTGAACAAATTAAACGACAACAACCAAAGCTGTCTCAAAAAGGCATCGAAATTCGAGTTTGTGGCTTGGCAAATAGTCG AGGTCTATTATTGGACAGCAAAGGGATTTCACTGGACGGATGGCGTGACCGAATGGGTAATGCGACCGAAGAGTTTAGTC TTGCTCGTTTAATCTCATTGGTTCAGCGTAACCATATTATTAACCCTGTGATTATTGATTGTACGTCTGATCATGGTATT GCTGCTCAATATGTTGATTTTCTATCGGCAGGTTTTCACGTTATTACTCCGAATAAAAAATCGAACACCGATTCTATGGC CTATTACCATCAGTTACGTAATGCAGCACGTGCAACGCGACGTAAGTTTATGTATGAGACGACGGTTGGTGCAGGTTTAC CTGTTATTGAAAACCTACAAAACCTAATTGCTGCTGGTGATGAGCTTGTAAAGTTTAATGGTATTTTATCCGGTTCTATG TCTTATATTTTTGGCAAGCTAGACGAAGGCATGTCATTAAGTGACGCTACGAATGTAGCGAAAAAAAATGGCTTTACTGA GCCCGATCCTCGAGATGATTTATCTGGTATGGATGTGGCTCGAAAACTTCTTATTCTTGCTCGCGAATCTGGCCTTGAAA TTGAATTAGATGACGTAGAGGTTGAACAAGCATTACCACCAGGCTTTGATGACTCAGGAACTATTGATGAATTCATGGCT CGTCTTCCAGAAGCGGATGCATATTTTGTTCAAGAGTCAGCTAAAGCCGCAGAGGAAGGCAAAGTATTACGTTATGTCGG TGAAATTTCAGAAGGGAAATGTAAGGTTCGAATTGCTGCCGTAGATGGTGATGATCCTATGTTTAAGATTAAAGACGGTG AAAATGCATTGGCATTCTACAGTCGTTACTATCAACCAATCCCATTGGTATTAAGAGGCTATGGCGCAGGAACAGAAGTA ACTGCTGCTGGCGTATTCTCTGATCTTATGCGCACCCTTGGCTGGAAATTAGGAGTATAA
Upstream 100 bases:
>100_bases ACTAATTCTTAACTGCATTCTTTCATTATTTACTGAAACGTTTATCATGCTAGAAGCAGTAAGGATACTGCAGTAACACT CGTTTTTAGGGAGGATAGAG
Downstream 100 bases:
>100_bases AATGAGTGTTGTTGTTTATGCTCCGGCATCGATTGGTAATGTAAGTGTTGGGTTTGATGTACTTGGTGCAGCGGTTTCTC CTATTGATGGTTCGCTATTA
Product: bifunctional aspartokinase I/homeserine dehydrogenase I
Products: NA
Alternate protein names: Aspartokinase I/homoserine dehydrogenase I; AKI-HDI; Aspartokinase; Homoserine dehydrogenase [H]
Number of amino acids: Translated: 819; Mature: 819
Protein sequence:
>819_residues MRVLKFGGSSLADSDRFLRAADIIANNAQQQDVSVVLSAPGKVTNKLVSVVDNVLTNGEAELQISELEAVFIQLFDGIST ALPQVDLKTLENKLKDSLSQLRQYVHGISLLGMCPDNVYAKIISKGERISVVTMKAVLEAKGQQASLIDPVKYLYARGSF LEGAVDVDISTLNFKNEPLPKGHVNIMPGFTAGNEKGELLTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGPGTLIGQDTGEDNLAIKGITTLSNLTMVNV SGPGMKGMVGMASRVFGAMSTAGISIVLITQSSSEYSISFCIEAEDKVQAEQVLREAFELELKDGLLEPVEFINDVAIVT LVGDGMRTSKGVASQFFTSLTEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL VEQIKRQQPKLSQKGIEIRVCGLANSRGLLLDSKGISLDGWRDRMGNATEEFSLARLISLVQRNHIINPVIIDCTSDHGI AAQYVDFLSAGFHVITPNKKSNTDSMAYYHQLRNAARATRRKFMYETTVGAGLPVIENLQNLIAAGDELVKFNGILSGSM SYIFGKLDEGMSLSDATNVAKKNGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTIDEFMA RLPEADAYFVQESAKAAEEGKVLRYVGEISEGKCKVRIAAVDGDDPMFKIKDGENALAFYSRYYQPIPLVLRGYGAGTEV TAAGVFSDLMRTLGWKLGV
Sequences:
>Translated_819_residues MRVLKFGGSSLADSDRFLRAADIIANNAQQQDVSVVLSAPGKVTNKLVSVVDNVLTNGEAELQISELEAVFIQLFDGIST ALPQVDLKTLENKLKDSLSQLRQYVHGISLLGMCPDNVYAKIISKGERISVVTMKAVLEAKGQQASLIDPVKYLYARGSF LEGAVDVDISTLNFKNEPLPKGHVNIMPGFTAGNEKGELLTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGPGTLIGQDTGEDNLAIKGITTLSNLTMVNV SGPGMKGMVGMASRVFGAMSTAGISIVLITQSSSEYSISFCIEAEDKVQAEQVLREAFELELKDGLLEPVEFINDVAIVT LVGDGMRTSKGVASQFFTSLTEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL VEQIKRQQPKLSQKGIEIRVCGLANSRGLLLDSKGISLDGWRDRMGNATEEFSLARLISLVQRNHIINPVIIDCTSDHGI AAQYVDFLSAGFHVITPNKKSNTDSMAYYHQLRNAARATRRKFMYETTVGAGLPVIENLQNLIAAGDELVKFNGILSGSM SYIFGKLDEGMSLSDATNVAKKNGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTIDEFMA RLPEADAYFVQESAKAAEEGKVLRYVGEISEGKCKVRIAAVDGDDPMFKIKDGENALAFYSRYYQPIPLVLRGYGAGTEV TAAGVFSDLMRTLGWKLGV >Mature_819_residues MRVLKFGGSSLADSDRFLRAADIIANNAQQQDVSVVLSAPGKVTNKLVSVVDNVLTNGEAELQISELEAVFIQLFDGIST ALPQVDLKTLENKLKDSLSQLRQYVHGISLLGMCPDNVYAKIISKGERISVVTMKAVLEAKGQQASLIDPVKYLYARGSF LEGAVDVDISTLNFKNEPLPKGHVNIMPGFTAGNEKGELLTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGPGTLIGQDTGEDNLAIKGITTLSNLTMVNV SGPGMKGMVGMASRVFGAMSTAGISIVLITQSSSEYSISFCIEAEDKVQAEQVLREAFELELKDGLLEPVEFINDVAIVT LVGDGMRTSKGVASQFFTSLTEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL VEQIKRQQPKLSQKGIEIRVCGLANSRGLLLDSKGISLDGWRDRMGNATEEFSLARLISLVQRNHIINPVIIDCTSDHGI AAQYVDFLSAGFHVITPNKKSNTDSMAYYHQLRNAARATRRKFMYETTVGAGLPVIENLQNLIAAGDELVKFNGILSGSM SYIFGKLDEGMSLSDATNVAKKNGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTIDEFMA RLPEADAYFVQESAKAAEEGKVLRYVGEISEGKCKVRIAAVDGDDPMFKIKDGENALAFYSRYYQPIPLVLRGYGAGTEV TAAGVFSDLMRTLGWKLGV
Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Escherichia coli, GI1786183, Length=820, Percent_Identity=61.3414634146341, Blast_Score=1048, Evalue=0.0, Organism=Escherichia coli, GI1790376, Length=819, Percent_Identity=32.8449328449328, Blast_Score=367, Evalue=1e-102, Organism=Escherichia coli, GI1790455, Length=461, Percent_Identity=29.5010845986985, Blast_Score=165, Evalue=9e-42, Organism=Saccharomyces cerevisiae, GI6322599, Length=340, Percent_Identity=33.8235294117647, Blast_Score=167, Evalue=8e-42, Organism=Saccharomyces cerevisiae, GI6320893, Length=541, Percent_Identity=28.4658040665434, Blast_Score=156, Evalue=1e-38,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005106 - InterPro: IPR001341 - InterPro: IPR018042 - InterPro: IPR011147 - InterPro: IPR001342 - InterPro: IPR019811 - InterPro: IPR016040 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT; PF00742 Homoserine_dh; PF03447 NAD_binding_3 [H]
EC number: =2.7.2.4; =1.1.1.3 [H]
Molecular weight: Translated: 88608; Mature: 88608
Theoretical pI: Translated: 4.72; Mature: 4.72
Prosite motif: PS01042 HOMOSER_DHGENASE ; PS00324 ASPARTOKINASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRVLKFGGSSLADSDRFLRAADIIANNAQQQDVSVVLSAPGKVTNKLVSVVDNVLTNGEA CEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC ELQISELEAVFIQLFDGISTALPQVDLKTLENKLKDSLSQLRQYVHGISLLGMCPDNVYA EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHH KIISKGERISVVTMKAVLEAKGQQASLIDPVKYLYARGSFLEGAVDVDISTLNFKNEPLP HHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCC KGHVNIMPGFTAGNEKGELLTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV CCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGPGTLIGQDTG HHHHHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCC EDNLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSTAGISIVLITQSSSEYSISF CCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEE CIEAEDKVQAEQVLREAFELELKDGLLEPVEFINDVAIVTLVGDGMRTSKGVASQFFTSL EEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHH TEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL HHCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHH VEQIKRQQPKLSQKGIEIRVCGLANSRGLLLDSKGISLDGWRDRMGNATEEFSLARLISL HHHHHHCCCCHHHCCCEEEEEECCCCCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHH VQRNHIINPVIIDCTSDHGIAAQYVDFLSAGFHVITPNKKSNTDSMAYYHQLRNAARATR HHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH RKFMYETTVGAGLPVIENLQNLIAAGDELVKFNGILSGSMSYIFGKLDEGMSLSDATNVA HHHHHHHHCCCCCHHHHHHHHHHHCCCHHEEECCEECCCHHHHHHHCCCCCCCHHHHHHH KKNGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTIDEFMA HHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCCCCCHHHHHH RLPEADAYFVQESAKAAEEGKVLRYVGEISEGKCKVRIAAVDGDDPMFKIKDGENALAFY HCCCCCHHHHHHHHHHHHCCCCEEEHHCCCCCEEEEEEEEECCCCCEEEEECCCCHHHHH SRYYQPIPLVLRGYGAGTEVTAAGVFSDLMRTLGWKLGV HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MRVLKFGGSSLADSDRFLRAADIIANNAQQQDVSVVLSAPGKVTNKLVSVVDNVLTNGEA CEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCC ELQISELEAVFIQLFDGISTALPQVDLKTLENKLKDSLSQLRQYVHGISLLGMCPDNVYA EEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCHHHHH KIISKGERISVVTMKAVLEAKGQQASLIDPVKYLYARGSFLEGAVDVDISTLNFKNEPLP HHHCCCCEEEEEEHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCC KGHVNIMPGFTAGNEKGELLTLGRNGSDYSAAVLAACLRAECCEIWTDVDGVYNCDPRLV CCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC DDARLLKSLSYQEAMELSYFGASVLHPKTIAPIAQFHIPCLIKNSFNPQGPGTLIGQDTG HHHHHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHCCCEEEECCCCCCCCCEEEECCCC EDNLAIKGITTLSNLTMVNVSGPGMKGMVGMASRVFGAMSTAGISIVLITQSSSEYSISF CCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEE CIEAEDKVQAEQVLREAFELELKDGLLEPVEFINDVAIVTLVGDGMRTSKGVASQFFTSL EEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHH TEVNVNIIAIAQGSSERAISAVIPEDKVSESIKACHENLFNSKHFLDVFVVGVGGVGGEL HHCCEEEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHH VEQIKRQQPKLSQKGIEIRVCGLANSRGLLLDSKGISLDGWRDRMGNATEEFSLARLISL HHHHHHCCCCHHHCCCEEEEEECCCCCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHHH VQRNHIINPVIIDCTSDHGIAAQYVDFLSAGFHVITPNKKSNTDSMAYYHQLRNAARATR HHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH RKFMYETTVGAGLPVIENLQNLIAAGDELVKFNGILSGSMSYIFGKLDEGMSLSDATNVA HHHHHHHHCCCCCHHHHHHHHHHHCCCHHEEECCEECCCHHHHHHHCCCCCCCHHHHHHH KKNGFTEPDPRDDLSGMDVARKLLILARESGLEIELDDVEVEQALPPGFDDSGTIDEFMA HHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHCCCCCCCCCCCHHHHHH RLPEADAYFVQESAKAAEEGKVLRYVGEISEGKCKVRIAAVDGDDPMFKIKDGENALAFY HCCCCCHHHHHHHHHHHHCCCCEEEHHCCCCCEEEEEEEEECCCCCEEEEECCCCHHHHH SRYYQPIPLVLRGYGAGTEVTAAGVFSDLMRTLGWKLGV HHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8423151 [H]