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The map label for this gene is hlyB [H]

Identifier: 209695630

GI number: 209695630

Start: 2355915

End: 2358008

Strand: Reverse

Name: hlyB [H]

Synonym: VSAL_I2193

Alternate gene names: 209695630

Gene position: 2358008-2355915 (Counterclockwise)

Preceding gene: 209695632

Following gene: 209695629

Centisome position: 70.91

GC content: 39.06

Gene sequence:

>2094_bases
ATGTTTAAATCAATAAAAACACGTATCGCGGTAAGTGCCGGACTTGCCATCTTTATAACATTAAGCACCGCCATGTTTTT
TACTACCGTATCTTATAACGGAGTAAATAAAGAAATAACAAAACATGTCTCTGACCAACTCGCTGAAAATATTGATTATA
AATTACTGTCTATTGCGAATCAGCAAAGTGCGGAACTCAATGGTCAATTTTCCCCAGTGATCAGTAACTTAAAACAACTA
AAATCATTGCTAGAACTGTCAAACCAACACCAAGCAGACGCAAGTCTTCTTATTGAGCAGTTCATCTCATCATTAAAAAT
ACAAAATGACAGTGTATTTGCAGGTTACATGGTGTGGGAAGACGCTAATTTTACTAAAGATGAATCGGTTCTTACTCAAA
AAGCATTAAATAAAGAAGGCGTTCTATCTCCATTCTTCTCTCCGACCAATTCAGGCTTTGAAGCCATTGGAATGGACCGC
TTTAAAAACACCGCGTTAAACAACAATGGTGAACGTACTGATGAATGGCATTTAGCGCCTTTTGAAACGGGTAAAAGCTT
TGTAATGGAACCTTACTATTACAACGTAAGAGGAAATGAAGAGCTTATTACGACGATCAGTTTGCCGTTACGACATAACA
ATAAGATTGTTGGTTCTCTTGGTTTTGACTGGTCAATAAAAAGCTTCCAAGCAATAAGTCAAAAATCAGCAAAAGCAACA
GGAATGCCTGATGCGATTGTCTCTATCGCCTCATGGGACGGACGATTACTATCTTTCAGTAAAGATGGAAGTTTAGTCGG
TCAAAAAGTAGCAGATGAATTTGCACGTAATTGGGGATCGATTCAGCAAGAAGCGAAAAATAATAAGTCATTCTTAAAAG
ACATCGGCCATTTGAAAATTGCTGTCTCTACCATTAATACAGGGGCAAAACCGTGGATAGTCATGGTGTCGATTCCTTCT
GAAATTTTGAAAAAAGAAATTACCGATTTCAATGTGTTCAGCACTGAATTAGGAAGCGAAGCACTTTCTAATGGTTTATT
AAGTGGCGTCATCTCTTCAATTGTTGGTATTTTTATTATTTTCCTTCTGGCAAAAAATATTGGTTCAACACTGTCTAATC
TCACGACTCGCTTTGAAAACATAGCTCAAGGTGATGGCGATTTAACACAGCGCATTGAGATAGACTCTAAAGACGAAATT
GGCCAGTTAGCTTTTTGGTTTAATACTTTTGTAGAGAAAATTCAACTCACTCTTCATAACGCCAAGAACACCGCTGAATT
GGTGTCTCAATCATCAATGAACACCATGTCTGAAACTGAAAAATCACAAATTAAGCTGCAAAATCAAGTGAATGAAGTGA
CCCAATTAGCAACGGCGATTAATGAAATGAGTGCAACGGCTCAAGAAGTTGCGTCTTCTGCTTTGCAAGCGGCAACCGCT
GCAAACCAAATTCAAACAAGCAGTGAAGATGGTCAAAAAATAATGAATAACGCCGCCTCTTCAGTAGAAGAGTTAGCCGC
ATTCATCAATGAAGCTCAATCACAAGTCGTTAGCTTAGCCGCATCAAGCAATGATATTCAAAAAATTCTAACGGAAATCG
GCAGCATTGCTGAGCAAACAAATTTATTGGCTCTGAATGCCGCGATTGAAGCAGCTCGTGCTGGTGAGCAAGGCCGTGGA
TTTGCAGTCGTCGCTGATGAGGTGCGTAACCTTGCAAGTCGTACGCAAAGCTCAACTCAAGAAATCAACAGCATGCTTGT
AATATTGCAGCAAAATACACAAGGCATTGTCACCGTAATGGACAGTAGCCAGAAACAAGCGCTAGCAACCAAAGAAGACA
CATTAATTGCACAACAAAACTTAATTGAAATAAGTAATGCAATCCTTGTGGCAAATGACATGAACAATCAAATTGCTTCT
GCCGCTGAAGAGCAAAGCTCGGTTTCTGAAGAGATAAATCGCAATGTAACCAGCATTAATGAAGCCGCTGATGAGGTTCT
TGCTGATATGCATACCTCACTCAATGATACGGCAGAACTAACAAGAGAAAGTCATGAATTAGCACAAAGGCTGAGTGAGT
TTAAAACTCAATAA

Upstream 100 bases:

>100_bases
CGGTGTAAATTTTATTCATTCAATTCAGTTATTTTAGCTAATGAATATTCACTCCAAGTCGATAAGTAATTCTATAAAAT
CATTTTAGTTCTGAGGGATT

Downstream 100 bases:

>100_bases
GCCCATCCAACAAAGCCACATGACTCTCCCTCGGTTGTGTGGCTTTCATCTCTTGACCTATTAATCCTCTTCCCCTCCTC
TCTATCTCTATCTCTATCTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MFKSIKTRIAVSAGLAIFITLSTAMFFTTVSYNGVNKEITKHVSDQLAENIDYKLLSIANQQSAELNGQFSPVISNLKQL
KSLLELSNQHQADASLLIEQFISSLKIQNDSVFAGYMVWEDANFTKDESVLTQKALNKEGVLSPFFSPTNSGFEAIGMDR
FKNTALNNNGERTDEWHLAPFETGKSFVMEPYYYNVRGNEELITTISLPLRHNNKIVGSLGFDWSIKSFQAISQKSAKAT
GMPDAIVSIASWDGRLLSFSKDGSLVGQKVADEFARNWGSIQQEAKNNKSFLKDIGHLKIAVSTINTGAKPWIVMVSIPS
EILKKEITDFNVFSTELGSEALSNGLLSGVISSIVGIFIIFLLAKNIGSTLSNLTTRFENIAQGDGDLTQRIEIDSKDEI
GQLAFWFNTFVEKIQLTLHNAKNTAELVSQSSMNTMSETEKSQIKLQNQVNEVTQLATAINEMSATAQEVASSALQAATA
ANQIQTSSEDGQKIMNNAASSVEELAAFINEAQSQVVSLAASSNDIQKILTEIGSIAEQTNLLALNAAIEAARAGEQGRG
FAVVADEVRNLASRTQSSTQEINSMLVILQQNTQGIVTVMDSSQKQALATKEDTLIAQQNLIEISNAILVANDMNNQIAS
AAEEQSSVSEEINRNVTSINEAADEVLADMHTSLNDTAELTRESHELAQRLSEFKTQ

Sequences:

>Translated_697_residues
MFKSIKTRIAVSAGLAIFITLSTAMFFTTVSYNGVNKEITKHVSDQLAENIDYKLLSIANQQSAELNGQFSPVISNLKQL
KSLLELSNQHQADASLLIEQFISSLKIQNDSVFAGYMVWEDANFTKDESVLTQKALNKEGVLSPFFSPTNSGFEAIGMDR
FKNTALNNNGERTDEWHLAPFETGKSFVMEPYYYNVRGNEELITTISLPLRHNNKIVGSLGFDWSIKSFQAISQKSAKAT
GMPDAIVSIASWDGRLLSFSKDGSLVGQKVADEFARNWGSIQQEAKNNKSFLKDIGHLKIAVSTINTGAKPWIVMVSIPS
EILKKEITDFNVFSTELGSEALSNGLLSGVISSIVGIFIIFLLAKNIGSTLSNLTTRFENIAQGDGDLTQRIEIDSKDEI
GQLAFWFNTFVEKIQLTLHNAKNTAELVSQSSMNTMSETEKSQIKLQNQVNEVTQLATAINEMSATAQEVASSALQAATA
ANQIQTSSEDGQKIMNNAASSVEELAAFINEAQSQVVSLAASSNDIQKILTEIGSIAEQTNLLALNAAIEAARAGEQGRG
FAVVADEVRNLASRTQSSTQEINSMLVILQQNTQGIVTVMDSSQKQALATKEDTLIAQQNLIEISNAILVANDMNNQIAS
AAEEQSSVSEEINRNVTSINEAADEVLADMHTSLNDTAELTRESHELAQRLSEFKTQ
>Mature_697_residues
MFKSIKTRIAVSAGLAIFITLSTAMFFTTVSYNGVNKEITKHVSDQLAENIDYKLLSIANQQSAELNGQFSPVISNLKQL
KSLLELSNQHQADASLLIEQFISSLKIQNDSVFAGYMVWEDANFTKDESVLTQKALNKEGVLSPFFSPTNSGFEAIGMDR
FKNTALNNNGERTDEWHLAPFETGKSFVMEPYYYNVRGNEELITTISLPLRHNNKIVGSLGFDWSIKSFQAISQKSAKAT
GMPDAIVSIASWDGRLLSFSKDGSLVGQKVADEFARNWGSIQQEAKNNKSFLKDIGHLKIAVSTINTGAKPWIVMVSIPS
EILKKEITDFNVFSTELGSEALSNGLLSGVISSIVGIFIIFLLAKNIGSTLSNLTTRFENIAQGDGDLTQRIEIDSKDEI
GQLAFWFNTFVEKIQLTLHNAKNTAELVSQSSMNTMSETEKSQIKLQNQVNEVTQLATAINEMSATAQEVASSALQAATA
ANQIQTSSEDGQKIMNNAASSVEELAAFINEAQSQVVSLAASSNDIQKILTEIGSIAEQTNLLALNAAIEAARAGEQGRG
FAVVADEVRNLASRTQSSTQEINSMLVILQQNTQGIVTVMDSSQKQALATKEDTLIAQQNLIEISNAILVANDMNNQIAS
AAEEQSSVSEEINRNVTSINEAADEVLADMHTSLNDTAELTRESHELAQRLSEFKTQ

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=320, Percent_Identity=29.0625, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1787690, Length=322, Percent_Identity=27.9503105590062, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788195, Length=263, Percent_Identity=30.0380228136882, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=346, Percent_Identity=27.1676300578035, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=187, Percent_Identity=31.5508021390374, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75990; Mature: 75990

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKSIKTRIAVSAGLAIFITLSTAMFFTTVSYNGVNKEITKHVSDQLAENIDYKLLSIAN
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
QQSAELNGQFSPVISNLKQLKSLLELSNQHQADASLLIEQFISSLKIQNDSVFAGYMVWE
CCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCEEEEEEEEE
DANFTKDESVLTQKALNKEGVLSPFFSPTNSGFEAIGMDRFKNTALNNNGERTDEWHLAP
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCC
FETGKSFVMEPYYYNVRGNEELITTISLPLRHNNKIVGSLGFDWSIKSFQAISQKSAKAT
HHCCCCEEECCEEEECCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCC
GMPDAIVSIASWDGRLLSFSKDGSLVGQKVADEFARNWGSIQQEAKNNKSFLKDIGHLKI
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEE
AVSTINTGAKPWIVMVSIPSEILKKEITDFNVFSTELGSEALSNGLLSGVISSIVGIFII
EEEECCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLAKNIGSTLSNLTTRFENIAQGDGDLTQRIEIDSKDEIGQLAFWFNTFVEKIQLTLHN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
AKNTAELVSQSSMNTMSETEKSQIKLQNQVNEVTQLATAINEMSATAQEVASSALQAATA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQIQTSSEDGQKIMNNAASSVEELAAFINEAQSQVVSLAASSNDIQKILTEIGSIAEQT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTQEINSMLVILQQNTQGIVTVM
CEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEE
DSSQKQALATKEDTLIAQQNLIEISNAILVANDMNNQIASAAEEQSSVSEEINRNVTSIN
CCCCHHHHHCHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHH
EAADEVLADMHTSLNDTAELTRESHELAQRLSEFKTQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKSIKTRIAVSAGLAIFITLSTAMFFTTVSYNGVNKEITKHVSDQLAENIDYKLLSIAN
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHCC
QQSAELNGQFSPVISNLKQLKSLLELSNQHQADASLLIEQFISSLKIQNDSVFAGYMVWE
CCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHEECCCCEEEEEEEEE
DANFTKDESVLTQKALNKEGVLSPFFSPTNSGFEAIGMDRFKNTALNNNGERTDEWHLAP
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCHHHHHHHHCCCCCCCCCCCCCCC
FETGKSFVMEPYYYNVRGNEELITTISLPLRHNNKIVGSLGFDWSIKSFQAISQKSAKAT
HHCCCCEEECCEEEECCCCCEEEEEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCC
GMPDAIVSIASWDGRLLSFSKDGSLVGQKVADEFARNWGSIQQEAKNNKSFLKDIGHLKI
CCCHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEE
AVSTINTGAKPWIVMVSIPSEILKKEITDFNVFSTELGSEALSNGLLSGVISSIVGIFII
EEEECCCCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLAKNIGSTLSNLTTRFENIAQGDGDLTQRIEIDSKDEIGQLAFWFNTFVEKIQLTLHN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHC
AKNTAELVSQSSMNTMSETEKSQIKLQNQVNEVTQLATAINEMSATAQEVASSALQAATA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANQIQTSSEDGQKIMNNAASSVEELAAFINEAQSQVVSLAASSNDIQKILTEIGSIAEQT
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
NLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSTQEINSMLVILQQNTQGIVTVM
CEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEE
DSSQKQALATKEDTLIAQQNLIEISNAILVANDMNNQIASAAEEQSSVSEEINRNVTSIN
CCCCHHHHHCHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHH
EAADEVLADMHTSLNDTAELTRESHELAQRLSEFKTQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]