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The map label for this gene is aapM [H]

Identifier: 209695502

GI number: 209695502

Start: 2201786

End: 2202883

Strand: Reverse

Name: aapM [H]

Synonym: VSAL_I2055

Alternate gene names: 209695502

Gene position: 2202883-2201786 (Counterclockwise)

Preceding gene: 209695503

Following gene: 209695501

Centisome position: 66.25

GC content: 41.26

Gene sequence:

>1098_bases
ATGAATACACATCAGTTTCAGCCAGATCTGCCGCCACCACCCAATACGGTAGGTGCTGTCACGTGGCTTAAAAGACATTT
ATTCAATGGTCCAATTAACTCAATTCTAACCCTTATTATCGGTTATCTTGCGTTTAGTGGGTTATGGAACGCTGTCAGTT
GGGCATTGATTAATGCCGATTGGATAGGAACAACGCGTGATGCCTGCTCTAGTGGAGGCGCGTGTTGGGTAATGATCAAC
GTTCGTTGGGACCAATTTATGTATGGTTTCTATCCAACGGCTGAGCTATGGCGACCTCAATTATTTTACGCATTACTCGC
TATTTTTGTTGCTTTGCTCGCTTATGAGCATACCCCTAAGAAAGTGGCTATTTGGTTAGTTTTTGTAAATATTTTCCCAT
TCTTTGCTGCCTTTTTATTGTATGGCGGCGTATTTGGGTTACCCGTTGTTGATACTCACCTTTGGGGAGGATTATTAATT
ACCTTAGTCATTGCGATTGTGGGTATTGTTGTGTCCTTGCCGATTGGGGTTGCTTTAGCCTTGGGTCGCCGTTCTGAAAT
GCCCATTATTCGTAGTATGTGTACTATCTACATTGAAATTTGGCGTGGTGTTCCTTTAATTACCGTTCTTTTCATGGCTT
CGGTCATGCTTCCCTTATTTTTATCGGAAGGAATGGAGTTAGATAAGCTATTTAGAGCCTTAATAGGGGTCGTCCTATTC
AGTGCTGCTTATATGGCAGAAGTTATTCGTGGTGGCTTACAAGCCATACCTAAAGGTCAATATGAAGCGGCAGATGCACT
TGGCTTAGGGTACTGGAAAAAGATGCGTTTAATTATTCTTCCTCAAGCCTTAAAAATCACTATCCCTTCCATAGTAAATA
CCTTTATTGGTTTATTTAAAGACACAAGCCTTGTACTCATTATTGGGATGTTTGATGTACTTGGTATTGGTCAAGCTGCA
AATACCGATCCTGAGTGGTTAGGATTTTCAACGGAAAGTTATGTCTTTGTCGCTTTGGTTTTCTGGGTGTTCTGTTTCTC
TATGTCGAGATACTCCATCTATTTAGAAAACAAACTTCATACAGGCCACAAGCGATAA

Upstream 100 bases:

>100_bases
TCATAACAATGACAATGGGCGTGTACCTTACATTAAGCCTGCTAACCTCATTCGTTATGAACATTTATAACAACAAAGTC
GCATTGGTTGAGAGGTAATT

Downstream 100 bases:

>100_bases
TTAACAGAATTCAAGGATGTAGTTATGACGACTCAACAAGATTATATGATCCAATTAGAAGACATGAACAAATGGTATGG
TCAATTTCATGTCCTTAAAA

Product: general L-amino acid ABC transporter permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNTHQFQPDLPPPPNTVGAVTWLKRHLFNGPINSILTLIIGYLAFSGLWNAVSWALINADWIGTTRDACSSGGACWVMIN
VRWDQFMYGFYPTAELWRPQLFYALLAIFVALLAYEHTPKKVAIWLVFVNIFPFFAAFLLYGGVFGLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTIYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVIRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR

Sequences:

>Translated_365_residues
MNTHQFQPDLPPPPNTVGAVTWLKRHLFNGPINSILTLIIGYLAFSGLWNAVSWALINADWIGTTRDACSSGGACWVMIN
VRWDQFMYGFYPTAELWRPQLFYALLAIFVALLAYEHTPKKVAIWLVFVNIFPFFAAFLLYGGVFGLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTIYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVIRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR
>Mature_365_residues
MNTHQFQPDLPPPPNTVGAVTWLKRHLFNGPINSILTLIIGYLAFSGLWNAVSWALINADWIGTTRDACSSGGACWVMIN
VRWDQFMYGFYPTAELWRPQLFYALLAIFVALLAYEHTPKKVAIWLVFVNIFPFFAAFLLYGGVFGLPVVDTHLWGGLLI
TLVIAIVGIVVSLPIGVALALGRRSEMPIIRSMCTIYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
SAAYMAEVIRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFKDTSLVLIIGMFDVLGIGQAA
NTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLHTGHKR

Specific function: Probably part of the binding-protein-dependent transport system ydhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=360, Percent_Identity=53.6111111111111, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1788226, Length=219, Percent_Identity=37.4429223744292, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=34.5971563981043, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787030, Length=162, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=28.2352941176471, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788645, Length=178, Percent_Identity=32.0224719101124, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788646, Length=220, Percent_Identity=28.1818181818182, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI48994930, Length=111, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787086, Length=173, Percent_Identity=30.0578034682081, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787087, Length=176, Percent_Identity=27.8409090909091, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40742; Mature: 40742

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHQFQPDLPPPPNTVGAVTWLKRHLFNGPINSILTLIIGYLAFSGLWNAVSWALINAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECC
WIGTTRDACSSGGACWVMINVRWDQFMYGFYPTAELWRPQLFYALLAIFVALLAYEHTPK
CCCCCHHHHCCCCEEEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
KVAIWLVFVNIFPFFAAFLLYGGVFGLPVVDTHLWGGLLITLVIAIVGIVVSLPIGVALA
HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRRSEMPIIRSMCTIYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SAAYMAEVIRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHHEEHHHHHHHHHHHHC
DTSLVLIIGMFDVLGIGQAANTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCC
TGHKR
CCCCC
>Mature Secondary Structure
MNTHQFQPDLPPPPNTVGAVTWLKRHLFNGPINSILTLIIGYLAFSGLWNAVSWALINAD
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECC
WIGTTRDACSSGGACWVMINVRWDQFMYGFYPTAELWRPQLFYALLAIFVALLAYEHTPK
CCCCCHHHHCCCCEEEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
KVAIWLVFVNIFPFFAAFLLYGGVFGLPVVDTHLWGGLLITLVIAIVGIVVSLPIGVALA
HHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRRSEMPIIRSMCTIYIEIWRGVPLITVLFMASVMLPLFLSEGMELDKLFRALIGVVLF
HCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SAAYMAEVIRGGLQAIPKGQYEAADALGLGYWKKMRLIILPQALKITIPSIVNTFIGLFK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHEEECHHHHEEHHHHHHHHHHHHC
DTSLVLIIGMFDVLGIGQAANTDPEWLGFSTESYVFVALVFWVFCFSMSRYSIYLENKLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCC
TGHKR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]