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The map label for this gene is focA [H]

Identifier: 209695416

GI number: 209695416

Start: 2096688

End: 2097548

Strand: Reverse

Name: focA [H]

Synonym: VSAL_I1956

Alternate gene names: 209695416

Gene position: 2097548-2096688 (Counterclockwise)

Preceding gene: 209695421

Following gene: 209695415

Centisome position: 63.08

GC content: 37.98

Gene sequence:

>861_bases
GTGAAAAAAGAATACAACCAATTCGATGCTATCGTTCCACCAGATATGGCTAAAAAAGCCGAAGATGTTGGTACTTATAA
AGCCACTAAAGCCCCTTTCCAATCTTTTTACCTTGCAATAACTGCTGGTGTATTTATTTCTATCGCCTTTGTATTCTATA
TTACCGTAACAACGGGTGCTGGCGATGCACCTTGGGGCATGGTTAAACTGGTTGGCGGTCTTGCCTTTAGCTTAGGTCTT
ATTCTTGTTGTTATCTGTGGTGGTGAACTATTTACCTCATCAGTATTAACTACCGTTGCAAGAGCAAGTAATAAAATCAC
AACGAGCCAATTATTAAAAAACTGGTGCATTGTGTATTTTGGTAACTTCATTGGTGCTATGTTTTTTGTTGCAATGATTT
GGTTTGCTAAAATGCATTTACTGGATAATGGACAATGGGGTCTTACTGCAATGAAAGTAGCGCAACACAAGCTACACCAT
ACTTTTGGTCAAGCAGTCGCTTTAGGTACATTGTGTAATCTGATGGTTTGTTTAGCGACTTGGATGACTTTCTCTTGTCG
TAGTAACTCTGATAAAGTACTTGTGATGCTATTACCAGTTGCAATGTTTGTTGCGGCAGGCTTTGAGCACAGTATTGCAA
ACATGTTTATGGTTCCACTAGGCATCGCAATTCATGCTTTTGCTAGTCCTGAATTCTGGACAGTAATCAATATTGACCCA
TCAGCATTTGCTGATTTGACAATAAGTAATTTTGTAGTAAATAATTTAATTCCAGTCACCATTGGTAATATTCTTGGTGG
CGGACTTTTAGTCGGTATTACTTATTGGAATATTTATTTAAAACCAGACGCACGTCATTAA

Upstream 100 bases:

>100_bases
TCAAAATTTATGTCACAAATAAATTATATTCGTATAATGATAAACAGACCCTAAAACTGAATGGTTTTATATTTCATATC
ATTACAAAGGACATCTGCTC

Downstream 100 bases:

>100_bases
TTCTTAATACAGAGATCAATGACTGAGCCTATTGTGATTGTTGTTTATTTCATCACAATAGATGTTATAGGAATGCTTGA
AACCCAGTACGGCATCCCTT

Product: formate transporter 1

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel 1 [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKKEYNQFDAIVPPDMAKKAEDVGTYKATKAPFQSFYLAITAGVFISIAFVFYITVTTGAGDAPWGMVKLVGGLAFSLGL
ILVVICGGELFTSSVLTTVARASNKITTSQLLKNWCIVYFGNFIGAMFFVAMIWFAKMHLLDNGQWGLTAMKVAQHKLHH
TFGQAVALGTLCNLMVCLATWMTFSCRSNSDKVLVMLLPVAMFVAAGFEHSIANMFMVPLGIAIHAFASPEFWTVINIDP
SAFADLTISNFVVNNLIPVTIGNILGGGLLVGITYWNIYLKPDARH

Sequences:

>Translated_286_residues
MKKEYNQFDAIVPPDMAKKAEDVGTYKATKAPFQSFYLAITAGVFISIAFVFYITVTTGAGDAPWGMVKLVGGLAFSLGL
ILVVICGGELFTSSVLTTVARASNKITTSQLLKNWCIVYFGNFIGAMFFVAMIWFAKMHLLDNGQWGLTAMKVAQHKLHH
TFGQAVALGTLCNLMVCLATWMTFSCRSNSDKVLVMLLPVAMFVAAGFEHSIANMFMVPLGIAIHAFASPEFWTVINIDP
SAFADLTISNFVVNNLIPVTIGNILGGGLLVGITYWNIYLKPDARH
>Mature_286_residues
MKKEYNQFDAIVPPDMAKKAEDVGTYKATKAPFQSFYLAITAGVFISIAFVFYITVTTGAGDAPWGMVKLVGGLAFSLGL
ILVVICGGELFTSSVLTTVARASNKITTSQLLKNWCIVYFGNFIGAMFFVAMIWFAKMHLLDNGQWGLTAMKVAQHKLHH
TFGQAVALGTLCNLMVCLATWMTFSCRSNSDKVLVMLLPVAMFVAAGFEHSIANMFMVPLGIAIHAFASPEFWTVINIDP
SAFADLTISNFVVNNLIPVTIGNILGGGLLVGITYWNIYLKPDARH

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=284, Percent_Identity=63.3802816901408, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1788837, Length=279, Percent_Identity=43.010752688172, Blast_Score=244, Evalue=4e-66,
Organism=Escherichia coli, GI87082249, Length=231, Percent_Identity=29.8701298701299, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321779, Length=203, Percent_Identity=26.6009852216749, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 31157; Mature: 31157

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEYNQFDAIVPPDMAKKAEDVGTYKATKAPFQSFYLAITAGVFISIAFVFYITVTTGA
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GDAPWGMVKLVGGLAFSLGLILVVICGGELFTSSVLTTVARASNKITTSQLLKNWCIVYF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GNFIGAMFFVAMIWFAKMHLLDNGQWGLTAMKVAQHKLHHTFGQAVALGTLCNLMVCLAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMTFSCRSNSDKVLVMLLPVAMFVAAGFEHSIANMFMVPLGIAIHAFASPEFWTVINIDP
HHEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEECH
SAFADLTISNFVVNNLIPVTIGNILGGGLLVGITYWNIYLKPDARH
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEEEEEEEEEECCCCCC
>Mature Secondary Structure
MKKEYNQFDAIVPPDMAKKAEDVGTYKATKAPFQSFYLAITAGVFISIAFVFYITVTTGA
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCC
GDAPWGMVKLVGGLAFSLGLILVVICGGELFTSSVLTTVARASNKITTSQLLKNWCIVYF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
GNFIGAMFFVAMIWFAKMHLLDNGQWGLTAMKVAQHKLHHTFGQAVALGTLCNLMVCLAT
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMTFSCRSNSDKVLVMLLPVAMFVAAGFEHSIANMFMVPLGIAIHAFASPEFWTVINIDP
HHEEECCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEECH
SAFADLTISNFVVNNLIPVTIGNILGGGLLVGITYWNIYLKPDARH
HHHHHHHHHHHHHHCCHHHHHHHHHCCHHEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]