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The map label for this gene is qor [C]

Identifier: 209695382

GI number: 209695382

Start: 2049660

End: 2050640

Strand: Reverse

Name: qor [C]

Synonym: VSAL_I1916

Alternate gene names: 209695382

Gene position: 2050640-2049660 (Counterclockwise)

Preceding gene: 209695383

Following gene: 209695375

Centisome position: 61.67

GC content: 38.94

Gene sequence:

>981_bases
ATGAGAGCAATTGTTCATCAATTTGGTTTAGCACCACAATCTATCACAGTAGAACCTTATACTTCAGAACCTTTGACTCC
CTTTCAGATTCAACTAAAAATGCGTTACAGCACAATAAACCCATCTGATTTAATTACCATTTCAGGGGCTTATCGCTCGC
GTATACCGCTCCCTTTTATTCCAGGTTTTGAAGGCCTTGGGATAATAAAAGAACGCTACGATTCACACTCTGCATTTTCT
ATTGGCGACCGAGTTCTCCCTATTGGCAGTGCTGGCGCATGGCAACGCTATCGAAATATAGACGAAAAATGGTGCTTTAC
GATCCCAAACCAACTAAGCGATGAACAAGCGGCAACCTCTTACATAAACCCAATGACAGCATGGCTGATCGTATCGGAAC
GCTTACATCGACACAAAGAAATGACATTAGTCATCAATGCGGCCAACTCAGCGATTGGACTCATACTGATACGGATGCTC
AATCATCTGGGAATAACGCCAATAGCATTGGTTCGTCGAGATAACACAGAAGCAGATTTTGAAGGATGTAATGTTCGTCG
CATCATCAATATACAAAATAAAAATAGCATACAGCAACTTTTGGAGAGTAAACAGAGTACTGGAATAGACGCGGTTCTTG
ATTGTGTTGGAGGGATAGAAGCCTTGCAATTATCACACTTACTTAAAGAAGGCGGACAATTCATTAACTACGGTTTATTA
TCAGGAAAACCAATCCCCCCTACTTTTTGGCGTGAACGACCTGATATTGATTTTTCTTATTTTCATCTAAGACAATGGAT
TCATTCTTCAGAAAAAAACATCATCCAAGAAAAACTCAATGAAGTCATGCTGCTCGTTTATAGTGGCATTGCAGATACGA
TCATTAGCGCTCATTTTTCTTTAAATGACATCCATAAAGCCATCACTTATATTCAAGATAAGAAAAAGACAAAAAAAGGA
AAAATACTGATTACATTTTAA

Upstream 100 bases:

>100_bases
GTCTCTAGTAAATAGACTTATCTCGGTAATTCTTTCATCATTCGTTCTGATATGTTACATATTGTCTTCCATTTTCAAGC
GCGTATCTAGGCAGTTATCA

Downstream 100 bases:

>100_bases
TGCTCTCGTTCAATACTGTATGGAATTAAAAACCGTATTGAACGACAAACGCATTATTTATTTAATTGTTTTTCCATTGA
TAAGTGCGGAATACCCGCTT

Product: alcohol dehydrogenase

Products: NADP(+); Semiquinone. [C]

Alternate protein names: Quinone Oxidoreductase; Oxidoreductase; NADPHQuinone Reductase; Zinc-Containing Alcohol Dehydrogenase Superfamily Protein; Alcohol Dehydrogenase GroES Domain-Containing Protein; Trans-2-Enoyl-CoA Reductase; Zn-Dependent Oxidoreductase; Alcohol Dehydrogenase GroES Domain Protein; Zinc-Dependent Oxidoreductase Protein; Dehydrogenase; Zn-Dependent Alcohol Dehydrogenase; Oxidoreductase Protein; Zinc-Containing Alcohol Dehydrogenase; Oxidoreductase Zinc-Containing Alcohol Dehydrogenase; Zinc-Containing Alcohol Dehydrogenase Superfamily; Oxidoreductase/Dehydrogenase; NADP-Dependent Quinone Oxidoreductase; Oxydoreductase Protein Zinc-Containing; Dehydrogenase/Oxidoreductase; Zinc-Dependent NADPHQuinone Oxidoreductase; Beta-Ketoacyl Synthase; Alcohol Dehydrogenase GroES-Like Protein; NADPH Quinone Oxidoreductase

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MRAIVHQFGLAPQSITVEPYTSEPLTPFQIQLKMRYSTINPSDLITISGAYRSRIPLPFIPGFEGLGIIKERYDSHSAFS
IGDRVLPIGSAGAWQRYRNIDEKWCFTIPNQLSDEQAATSYINPMTAWLIVSERLHRHKEMTLVINAANSAIGLILIRML
NHLGITPIALVRRDNTEADFEGCNVRRIINIQNKNSIQQLLESKQSTGIDAVLDCVGGIEALQLSHLLKEGGQFINYGLL
SGKPIPPTFWRERPDIDFSYFHLRQWIHSSEKNIIQEKLNEVMLLVYSGIADTIISAHFSLNDIHKAITYIQDKKKTKKG
KILITF

Sequences:

>Translated_326_residues
MRAIVHQFGLAPQSITVEPYTSEPLTPFQIQLKMRYSTINPSDLITISGAYRSRIPLPFIPGFEGLGIIKERYDSHSAFS
IGDRVLPIGSAGAWQRYRNIDEKWCFTIPNQLSDEQAATSYINPMTAWLIVSERLHRHKEMTLVINAANSAIGLILIRML
NHLGITPIALVRRDNTEADFEGCNVRRIINIQNKNSIQQLLESKQSTGIDAVLDCVGGIEALQLSHLLKEGGQFINYGLL
SGKPIPPTFWRERPDIDFSYFHLRQWIHSSEKNIIQEKLNEVMLLVYSGIADTIISAHFSLNDIHKAITYIQDKKKTKKG
KILITF
>Mature_326_residues
MRAIVHQFGLAPQSITVEPYTSEPLTPFQIQLKMRYSTINPSDLITISGAYRSRIPLPFIPGFEGLGIIKERYDSHSAFS
IGDRVLPIGSAGAWQRYRNIDEKWCFTIPNQLSDEQAATSYINPMTAWLIVSERLHRHKEMTLVINAANSAIGLILIRML
NHLGITPIALVRRDNTEADFEGCNVRRIINIQNKNSIQQLLESKQSTGIDAVLDCVGGIEALQLSHLLKEGGQFINYGLL
SGKPIPPTFWRERPDIDFSYFHLRQWIHSSEKNIIQEKLNEVMLLVYSGIADTIISAHFSLNDIHKAITYIQDKKKTKKG
KILITF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=22.9299363057325, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078404, Length=291, Percent_Identity=23.3676975945017, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI67078406, Length=287, Percent_Identity=23.3449477351916, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI24308257, Length=211, Percent_Identity=24.6445497630332, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI194239674, Length=312, Percent_Identity=21.7948717948718, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI13236495, Length=312, Percent_Identity=21.7948717948718, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=337, Percent_Identity=24.0356083086053, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536829, Length=262, Percent_Identity=32.0610687022901, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17556000, Length=236, Percent_Identity=33.0508474576271, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=237, Percent_Identity=25.3164556962025, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45550423, Length=267, Percent_Identity=25.0936329588015, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.5.5 [C]

Molecular weight: Translated: 36927; Mature: 36927

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIVHQFGLAPQSITVEPYTSEPLTPFQIQLKMRYSTINPSDLITISGAYRSRIPLPFI
CCCHHHHHCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCEEEEECCHHCCCCCCCC
PGFEGLGIIKERYDSHSAFSIGDRVLPIGSAGAWQRYRNIDEKWCFTIPNQLSDEQAATS
CCCCCCHHHHHHCCCCCCEECCCEEEECCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHH
YINPMTAWLIVSERLHRHKEMTLVINAANSAIGLILIRMLNHLGITPIALVRRDNTEADF
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
EGCNVRRIINIQNKNSIQQLLESKQSTGIDAVLDCVGGIEALQLSHLLKEGGQFINYGLL
CCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECC
SGKPIPPTFWRERPDIDFSYFHLRQWIHSSEKNIIQEKLNEVMLLVYSGIADTIISAHFS
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNDIHKAITYIQDKKKTKKGKILITF
HHHHHHHHHHHHHHCCCCCCCEEEEC
>Mature Secondary Structure
MRAIVHQFGLAPQSITVEPYTSEPLTPFQIQLKMRYSTINPSDLITISGAYRSRIPLPFI
CCCHHHHHCCCCCCEEECCCCCCCCCCEEEEEEEEECCCCCCCEEEEECCHHCCCCCCCC
PGFEGLGIIKERYDSHSAFSIGDRVLPIGSAGAWQRYRNIDEKWCFTIPNQLSDEQAATS
CCCCCCHHHHHHCCCCCCEECCCEEEECCCCHHHHHHHCCCCCEEEECCCCCCCHHHHHH
YINPMTAWLIVSERLHRHKEMTLVINAANSAIGLILIRMLNHLGITPIALVRRDNTEADF
HHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
EGCNVRRIINIQNKNSIQQLLESKQSTGIDAVLDCVGGIEALQLSHLLKEGGQFINYGLL
CCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECC
SGKPIPPTFWRERPDIDFSYFHLRQWIHSSEKNIIQEKLNEVMLLVYSGIADTIISAHFS
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LNDIHKAITYIQDKKKTKKGKILITF
HHHHHHHHHHHHHHCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.017 {9,10-phenanthrenequinone}} 0.0153 {2,6-dichlorophenolindophenol}} 0.013 {2,6-dichlorophenolindophenol}} 0.065 {1,4-benzoquinone}} 0.007 {NADPH}} 0.0069 {NADPH}} 0.26 {1,4-naphthoquinone}} 0.0024 {1,2-naphthoquinone}} [C]

Substrates: NADPH; Quinone [C]

Specific reaction: NADPH + Quinone = NADP(+) + Semiquinone. [C]

General reaction: Oxidation; Reduction [C]

Inhibitor: 2, 3-Dimercaptopropanol; 2, 5-Dichloro-3, 6-dihydroxy -1, 4-benzoquinone; 4-Hydroxy coumarin; 5, 5'-Dithiobis (2-nitrobenzoate); ADP; Cibacronblue3GA; Coumarin; Cu2+; Dicoumarol warfarin, coumarin; Dithiothreitol preincubation with 9, 10-phenanthrenequino

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA