Click here to switch to the map view.

The map label for this gene is cmoA

Identifier: 209695352

GI number: 209695352

Start: 2019787

End: 2020515

Strand: Reverse

Name: cmoA

Synonym: VSAL_I1885

Alternate gene names: 209695352

Gene position: 2020515-2019787 (Counterclockwise)

Preceding gene: 209695369

Following gene: 209695351

Centisome position: 60.76

GC content: 39.64

Gene sequence:

>729_bases
ATGGCTAACCCAGATACTATATTTTCAGCTCCAATCGATAAAATTGGTGACTTTACCTTTGACGAACGTGTCGCAGAAGT
ATTTCCAGATATGATTCAACGTTCAATTCCAGGCTACAGCAACATTATCTCTGCTATTGGTATGCTTGCTGAACGTTACG
CTAAACCTCATTCAAGTGTTTATGATTTAGGTTGCTCACTGGGTGCGGCAACGTTATCTATGCGTCGTCACATTAATCAA
GAAGGCTGTCAGATTATTGGAGTCGATAATTCCTCAGCAATGGTCGAACGTTGTCGTTTACTGATTAACGCTTATCGTTC
AGATACACCCGTAACCATTGTTGAAGCGGATATCCGTGATGTCAATATTCAAGATGCATCGGTCGTCGTATTAAATTTTA
CTTTGCAATTTTTAGTGCCAGCCGATCGTAGAGCCCTATTGGAGAAAATCTATTCTGGATTACGTCCCGGTGGCATTCTT
ATTTTATCTGAGAAATACATCTTCGAAGATGGTGTCGTTAACGAGTTATTGATCGATTTACATCATGATTTCAAACGTGC
TAATGGCTATAGTGAATTAGAAATAAGCCAAAAGCGCAGCGCCATTGAAAATGTCATGCTGCCAGATCCAATTGATGTTC
ACAAACAACGTTTTCAAGAGATTGGCTTTAAAAGCTCTGAAGTCTGGTTCCAATGCTTTAATTTTGGCTCAATGTTCGCG
ATCAAATAA

Upstream 100 bases:

>100_bases
AATGACGTAATCATGATTAAGTAAACAAAAACAACTTAATCATGATTGGTATTGGTTGATAGTACGTATGGACATAACAA
CGCGTCTTTGTGAGAAAACC

Downstream 100 bases:

>100_bases
TCGATATAAATCCTTTATTTTCACTTATTAATTAACTAAAGATATTTCAATGTTTAATTTTGCTAATTTTTATAAACTTA
TTGCTCAAGATACCATTCTT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSVYDLGCSLGAATLSMRRHINQ
EGCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRDVNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGIL
ILSEKYIFEDGVVNELLIDLHHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFA
IK

Sequences:

>Translated_242_residues
MANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSVYDLGCSLGAATLSMRRHINQ
EGCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRDVNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGIL
ILSEKYIFEDGVVNELLIDLHHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFA
IK
>Mature_241_residues
ANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSVYDLGCSLGAATLSMRRHINQE
GCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRDVNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGILI
LSEKYIFEDGVVNELLIDLHHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFAI
K

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=242, Percent_Identity=68.1818181818182, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_ALISL (B6EGJ0)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002263281.1
- ProteinModelPortal:   B6EGJ0
- GeneID:   6987435
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1885
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK874240
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27213; Mature: 27081

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: BINDING 39-39 BINDING 89-89 BINDING 132-132 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSV
CCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
YDLGCSLGAATLSMRRHINQEGCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRD
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGILILSEKYIFEDGVVNELLIDL
CCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHHCCCHHHHHHHHH
HHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
IK
EC
>Mature Secondary Structure 
ANPDTIFSAPIDKIGDFTFDERVAEVFPDMIQRSIPGYSNIISAIGMLAERYAKPHSSV
CCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
YDLGCSLGAATLSMRRHINQEGCQIIGVDNSSAMVERCRLLINAYRSDTPVTIVEADIRD
HHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
VNIQDASVVVLNFTLQFLVPADRRALLEKIYSGLRPGGILILSEKYIFEDGVVNELLIDL
CCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHCCCCCCEEEEECCHHHCCCHHHHHHHHH
HHDFKRANGYSELEISQKRSAIENVMLPDPIDVHKQRFQEIGFKSSEVWFQCFNFGSMFA
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCEEE
IK
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA