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The map label for this gene is yeaD [H]

Identifier: 209695315

GI number: 209695315

Start: 1983456

End: 1984331

Strand: Reverse

Name: yeaD [H]

Synonym: VSAL_I1848

Alternate gene names: 209695315

Gene position: 1984331-1983456 (Counterclockwise)

Preceding gene: 209695316

Following gene: 209695313

Centisome position: 59.68

GC content: 40.53

Gene sequence:

>876_bases
ATGGATTTAACTCAATTATCAACGATTAGTGCCCTTTCTGATAGTGTCACAATTGAACAACTAGACGATGTAAAAATCGT
CCGAGTGCGTCACAGTAAAGCTGAAGCGGCAATATCACTTCATGGTGGTCATGTGTTATCTTTTAAGCCAACGCAAGGTG
AAGAGCTTATCTGGATGAGCAAAGACGCTATCTTCCACCCAGACAAAGCCATTCGTGGCGGTGTGCCTGTATGTTGGCCT
TGGTTTGGACGTATAGAAAACCCAGCTCATGGGTTTGCTCGTAACAGCCAATGGACATTAATTGAACATAAAGAAAATGA
AAACGGTGTAATGATTTCTCTAGGCTTGTCGGCTTCAGAAGAAACAAAAGCAATCTGGCCTTTTGAGTTTGAAGCACGAT
TAAATATAACTATCGGCGATGAGCTAACCATTACACTTGATGCAAAAAATACAGATAACAAACCTTGGAATTGCTCTGGT
GCGTTACATACCTATCTAAACATCTCTGATATCCATACGTCTGTCATCACCGGAATGGGAGATCGTTACATTGATGGTCT
ATTAAATGGAACAAGCTGTACTGGTGAGCATGAGCTTAAGATCAATGAAGCCGTAGATCGTGTTTACACAGAATCAGAAT
CAACGTTAACCATTAGCGATAACCTTCGTACAATTACAGTAACTAATGAGGGTAATAATGCCGCGGTTATCTGGAACCCA
TGGGCAGAAGGTGCAGAAAGCATGGGAGACATGAATAATGATGGGTATTTAACAATGGTCTGCATTGAATCGACTTATCA
CGCAACAAGTTTAGAAACAGCAAAAACAATTCAACCAAATGAATCATTCACACTAAGTACGATTATTCGCGCTTAA

Upstream 100 bases:

>100_bases
TTTTTTGTATCTGTTATTTGATATATTCTCTTTTTAGTATTTATTCAATTGTCATGTATAAATTACAATTGAATAAATAT
TACCTTTCTAGGAGATAGAC

Downstream 100 bases:

>100_bases
TTGAACCAATAAAAAAGCGGAGATAAAATTAATTATCTCCGCTTTCTTTCATTCTAAGCACACTGTTATTATCTTTCCCA
GTATGACTCTTCTAAACTGT

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MDLTQLSTISALSDSVTIEQLDDVKIVRVRHSKAEAAISLHGGHVLSFKPTQGEELIWMSKDAIFHPDKAIRGGVPVCWP
WFGRIENPAHGFARNSQWTLIEHKENENGVMISLGLSASEETKAIWPFEFEARLNITIGDELTITLDAKNTDNKPWNCSG
ALHTYLNISDIHTSVITGMGDRYIDGLLNGTSCTGEHELKINEAVDRVYTESESTLTISDNLRTITVTNEGNNAAVIWNP
WAEGAESMGDMNNDGYLTMVCIESTYHATSLETAKTIQPNESFTLSTIIRA

Sequences:

>Translated_291_residues
MDLTQLSTISALSDSVTIEQLDDVKIVRVRHSKAEAAISLHGGHVLSFKPTQGEELIWMSKDAIFHPDKAIRGGVPVCWP
WFGRIENPAHGFARNSQWTLIEHKENENGVMISLGLSASEETKAIWPFEFEARLNITIGDELTITLDAKNTDNKPWNCSG
ALHTYLNISDIHTSVITGMGDRYIDGLLNGTSCTGEHELKINEAVDRVYTESESTLTISDNLRTITVTNEGNNAAVIWNP
WAEGAESMGDMNNDGYLTMVCIESTYHATSLETAKTIQPNESFTLSTIIRA
>Mature_291_residues
MDLTQLSTISALSDSVTIEQLDDVKIVRVRHSKAEAAISLHGGHVLSFKPTQGEELIWMSKDAIFHPDKAIRGGVPVCWP
WFGRIENPAHGFARNSQWTLIEHKENENGVMISLGLSASEETKAIWPFEFEARLNITIGDELTITLDAKNTDNKPWNCSG
ALHTYLNISDIHTSVITGMGDRYIDGLLNGTSCTGEHELKINEAVDRVYTESESTLTISDNLRTITVTNEGNNAAVIWNP
WAEGAESMGDMNNDGYLTMVCIESTYHATSLETAKTIQPNESFTLSTIIRA

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=276, Percent_Identity=36.9565217391304, Blast_Score=194, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6323746, Length=240, Percent_Identity=29.5833333333333, Blast_Score=105, Evalue=6e-24,
Organism=Drosophila melanogaster, GI19921284, Length=274, Percent_Identity=30.2919708029197, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28574481, Length=175, Percent_Identity=26.8571428571429, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 32138; Mature: 32138

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTQLSTISALSDSVTIEQLDDVKIVRVRHSKAEAAISLHGGHVLSFKPTQGEELIWMS
CCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCEEEEECCCEEEEECCCCCCEEEEEE
KDAIFHPDKAIRGGVPVCWPWFGRIENPAHGFARNSQWTLIEHKENENGVMISLGLSASE
CCCEECCCHHHHCCCCEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCC
ETKAIWPFEFEARLNITIGDELTITLDAKNTDNKPWNCSGALHTYLNISDIHTSVITGMG
CCCEECCEEEEEEEEEEECCEEEEEEECCCCCCCCEECCCEEEEEEEEHHHHHHHHHCCC
DRYIDGLLNGTSCTGEHELKINEAVDRVYTESESTLTISDNLRTITVTNEGNNAAVIWNP
CHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCEEEEECC
WAEGAESMGDMNNDGYLTMVCIESTYHATSLETAKTIQPNESFTLSTIIRA
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHEEECCCCCEEEEEEECC
>Mature Secondary Structure
MDLTQLSTISALSDSVTIEQLDDVKIVRVRHSKAEAAISLHGGHVLSFKPTQGEELIWMS
CCCHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCEEEEECCCEEEEECCCCCCEEEEEE
KDAIFHPDKAIRGGVPVCWPWFGRIENPAHGFARNSQWTLIEHKENENGVMISLGLSASE
CCCEECCCHHHHCCCCEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCC
ETKAIWPFEFEARLNITIGDELTITLDAKNTDNKPWNCSGALHTYLNISDIHTSVITGMG
CCCEECCEEEEEEEEEEECCEEEEEEECCCCCCCCEECCCEEEEEEEEHHHHHHHHHCCC
DRYIDGLLNGTSCTGEHELKINEAVDRVYTESESTLTISDNLRTITVTNEGNNAAVIWNP
CHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEECCEEEEEEEECCCCEEEEECC
WAEGAESMGDMNNDGYLTMVCIESTYHATSLETAKTIQPNESFTLSTIIRA
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]