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The map label for this gene is gap [H]

Identifier: 209695316

GI number: 209695316

Start: 1984513

End: 1985505

Strand: Reverse

Name: gap [H]

Synonym: VSAL_I1849

Alternate gene names: 209695316

Gene position: 1985505-1984513 (Counterclockwise)

Preceding gene: 209695318

Following gene: 209695315

Centisome position: 59.71

GC content: 43.2

Gene sequence:

>993_bases
ATGACTATCAAAGTAGGTATTAACGGTTTTGGCCGTATTGGACGTTTTGTTTTCCGTGCATCTGTAGAGCGCAACGACAT
CGAAGTTGTTGGTATTAACGATCTTATCGACGTTGAATACATGGCTTACATGCTTAAGTACGACTCAACTCACGGTCGTT
TCAACGGTACTGTTGAAGTAGTTGACGGTAACCTAGTAGTTAACGGTAACACTGTACGTGTAACTGCTGAACGTAACCCA
GAAGATCTTAAGTGGGATGCAATCAACGTTGACGTTGTTGCTGAAGCTACTGGTCTTTTCCTTACTGACGAAACTGCTCG
TAAACACATCACAGCTGGCGCTAAGAAAGTAGTTCTTACTGGTCCTTCTGGTGACGTTCCAATGTTCGTTATGGGCGTTA
ACGCTGCAGATTACGCTGGTCAAGATATCGTTTCTAACGCTTCTTGTACTACTAACTGTCTTGCACCTATCGCTAAAGTA
CTTAACGACAAGTGGGGCATTGAATCTGGTCTTATGACTACAGTTCACGCAACTACAGCAACTCAAAAAACTGTAGATGG
TCCTTCTGCGAAAGACTGGCGTGGTGGCCGTGGTGCTTCTCAAAACATCATCCCATCTTCAACTGGTGCAGCTAAAGCAG
TAGGTAAAGTAATTCCTGAGCTTAACGGCCTTCTAACTGGTATGGCTTTCCGCGTACCAACTGCAAACGTTTCTGTTGTT
GACCTTACAGTTAACCTAAAAACTGCTGCAACTTACGAAGAAATCTGTGCTGAAATGAAACGCGCTTCTGAAAATGAATT
TGCTGGCGTTTTAGGCTACACAGAAGAAGCTGTTGTTTCTCAAGACTTCATCGGCGAAACACAAACTTCAGTATTTGATG
CTGCAGCTGGTGTTGCTCTAACTGACAAATTCGTTAAGCTTGTATCTTGGTACGACAACGAAATCGGTTACTCAAACAAA
GTTCTTGACCTAATCGCTCACGTTTCTAAGTAA

Upstream 100 bases:

>100_bases
TAAATGGCATTTTCGCTTGCAGGTTGGCTCAGGATTTTGTAATTTTACTACCAGTTAATTTAAACCTGAAAATCAAATTT
AAGTTGTGGAGCAACATATA

Downstream 100 bases:

>100_bases
GCATTAGTTTAGACTTTCTTTGAAAACTAACTTGAAAGGTTTCATTATCTTTTAAGTATAAAAGGCGACTTAATTGTCGC
CTTTTTTGTATCTGTTATTT

Product: glyceraldehydes-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGNTVRVTAERNP
EDLKWDAINVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVMGVNAADYAGQDIVSNASCTTNCLAPIAKV
LNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGLLTGMAFRVPTANVSVV
DLTVNLKTAATYEEICAEMKRASENEFAGVLGYTEEAVVSQDFIGETQTSVFDAAAGVALTDKFVKLVSWYDNEIGYSNK
VLDLIAHVSK

Sequences:

>Translated_330_residues
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGNTVRVTAERNP
EDLKWDAINVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVMGVNAADYAGQDIVSNASCTTNCLAPIAKV
LNDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGLLTGMAFRVPTANVSVV
DLTVNLKTAATYEEICAEMKRASENEFAGVLGYTEEAVVSQDFIGETQTSVFDAAAGVALTDKFVKLVSWYDNEIGYSNK
VLDLIAHVSK
>Mature_329_residues
TIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEVVDGNLVVNGNTVRVTAERNPE
DLKWDAINVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVMGVNAADYAGQDIVSNASCTTNCLAPIAKVL
NDKWGIESGLMTTVHATTATQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGLLTGMAFRVPTANVSVVD
LTVNLKTAATYEEICAEMKRASENEFAGVLGYTEEAVVSQDFIGETQTSVFDAAAGVALTDKFVKLVSWYDNEIGYSNKV
LDLIAHVSK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=62.0060790273556, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=59.5744680851064, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=80.0604229607251, Blast_Score=539, Evalue=1e-155,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=41.3373860182371, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=58.5585585585586, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=58.5585585585586, Blast_Score=399, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=57.185628742515, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=56.5868263473054, Blast_Score=392, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=63.030303030303, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=63.030303030303, Blast_Score=433, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=63.030303030303, Blast_Score=429, Evalue=1e-121,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=62.3853211009174, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=62.3853211009174, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI17933600, Length=328, Percent_Identity=61.5853658536585, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI18110149, Length=328, Percent_Identity=61.5853658536585, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI19922412, Length=325, Percent_Identity=57.5384615384615, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35221; Mature: 35090

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEV
CEEEEECCCHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDGNLVVNGNTVRVTAERNPEDLKWDAINVDVVAEATGLFLTDETARKHITAGAKKVVLT
EECEEEEECCEEEEEECCCCCCCEEEEEEEEEEEECCCEEEECHHHHHHHCCCCCEEEEE
GPSGDVPMFVMGVNAADYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTA
CCCCCCCEEEEECCCHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGLLTGMAFRVPTANVSVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
DLTVNLKTAATYEEICAEMKRASENEFAGVLGYTEEAVVSQDFIGETQTSVFDAAAGVAL
EEEEEEECHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHCCHHH
TDKFVKLVSWYDNEIGYSNKVLDLIAHVSK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGINGFGRIGRFVFRASVERNDIEVVGINDLIDVEYMAYMLKYDSTHGRFNGTVEV
EEEEECCCHHHHHHHHHEECCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEE
VDGNLVVNGNTVRVTAERNPEDLKWDAINVDVVAEATGLFLTDETARKHITAGAKKVVLT
EECEEEEECCEEEEEECCCCCCCEEEEEEEEEEEECCCEEEECHHHHHHHCCCCCEEEEE
GPSGDVPMFVMGVNAADYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTA
CCCCCCCEEEEECCCHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TQKTVDGPSAKDWRGGRGASQNIIPSSTGAAKAVGKVIPELNGLLTGMAFRVPTANVSVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEE
DLTVNLKTAATYEEICAEMKRASENEFAGVLGYTEEAVVSQDFIGETQTSVFDAAAGVAL
EEEEEEECHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHHHHCCHHH
TDKFVKLVSWYDNEIGYSNKVLDLIAHVSK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]