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The map label for this gene is yhcK [H]

Identifier: 209695294

GI number: 209695294

Start: 1949687

End: 1951135

Strand: Reverse

Name: yhcK [H]

Synonym: VSAL_I1824

Alternate gene names: 209695294

Gene position: 1951135-1949687 (Counterclockwise)

Preceding gene: 209695299

Following gene: 209695293

Centisome position: 58.68

GC content: 37.13

Gene sequence:

>1449_bases
ATGCATTTTGTATATAATTCAAATTTAGAAAGCAATCGTCAGCTTTTTAGCAAAGAAGCGGAACGTGAATCAACCTTACT
TACTTTATTAATAGAAAAAGACATCGATTTTATTGGCGCGGGCGCAAACTTCTATCAGGGGGGCTCCAAACAAGACTGGC
AACAATTTCCCTTATTTGCTAATTCATTACTCTCTCGCTCACAAAGTTTAATTTCCCTTCAATGGATGCAAAAAGTAGAA
GAAAAGGACATTGAGAAGCACAGTAAAGAAGTTAAAAAAATCTTTCCGTCTTTTTCTATTTATACCGTACCTCAAGATAA
GCCTAAAACGTACGATTACGTATTTAAAAATCATGAACCGATTTATGTTGCGACAGATATTTATCCAAGAGATAAGAAAA
ATATAGCACTATTAGGTTTTTATTCAGCACAAGAACGCTTTCAACGAGTGGTTGATGAATCAATTAAAGTGGGTCGCCCA
AGCATTTCGGATAAAGTTCGTCTTTTACAAGACGGTTTAGATAAAAGCACACCCAAAACGGGCTTATTGGTCTATCATCC
GGTATTTACTGCGGACAAAAAAGCATTGAAAGGCATCATGGTTGGGGTACTTAGAGTAACAAGCTATTTTGATAAGTTGG
TCGAATCCACATTGCTTGGAGAATCTTTAGTCGTAAAAATTATCGATACTGGGTTTGATGCAGAGGATGACCCTATCATG
TTTGAAAGCCCACAATGGGATGATTTTAATGGCTTACGTATTACTAACTCTATAAATATTGAAAATAGAATTTGGCATGT
GGAGTACAAAAGTAAGAACGATTTAAGTGATAGCCAACAACTGAGTTTATTATGGATGTTTATTGGGGCTCTTATTTTAT
CTAACTTGATTGCCGTCATTACTTTTATGGTTACTCGAGATAAAAAACGTATTGAGAAATTACTAGAAGCTCGGACGGAA
GAATTGCATTACATGGCAATGCATGATGATCTTACGGGGTTATTGAATCGTCGTTCAATGACAAAAGTAGTGAATCGATT
TATAGAAGAAGACAAACCATTTGCATTGATCTGCTTTGATATCGATAACTTTAAAGACATTAATGATACCTATGGGCATC
CGGAAGGGGATGAGGTTTTGCTTCATATTACTTATCTTGTTTCTGATCTTTTAGGAGAAGCTACGCCAATAATACGGTTG
GGTGGCGATGAGTTTGCTGTTCTGCTTGAAATAGGCGATCTTCAGCAATTATCGCATGTGGCGAAGAAAATTCATCAGGT
TATCGAAGAATCACCAACCATCATCCCTGATCTTATTATCGAACAAACCATCAGTTTAGGTGCCGTACTCTGGAGAGGTG
AACGGAAAGAGGTTTTACTTAAATTGGCAGACCAAGCGTTGTACGATAGTAAAGACAGAGGCAGAAACCAAGTAACTATT
CGTGGCTGA

Upstream 100 bases:

>100_bases
ATGACGGCTTACTGAATTTAGAGGTTGAAGAGTGTTTAAGAATAGTTCTATTCATATAATAACCAGTTTTATGCTGGCAC
TGACTTTAAGCTTGTTATGT

Downstream 100 bases:

>100_bases
TTTTTCATCAAACGAATAGCAGAGTCTCGCGTAAGCGCTTTTGATTTAGTAGAATACCCATCTACTAAATGTTGAGTCAC
CAAAGGAACACCATGAACTT

Product: membrane associated receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MHFVYNSNLESNRQLFSKEAERESTLLTLLIEKDIDFIGAGANFYQGGSKQDWQQFPLFANSLLSRSQSLISLQWMQKVE
EKDIEKHSKEVKKIFPSFSIYTVPQDKPKTYDYVFKNHEPIYVATDIYPRDKKNIALLGFYSAQERFQRVVDESIKVGRP
SISDKVRLLQDGLDKSTPKTGLLVYHPVFTADKKALKGIMVGVLRVTSYFDKLVESTLLGESLVVKIIDTGFDAEDDPIM
FESPQWDDFNGLRITNSINIENRIWHVEYKSKNDLSDSQQLSLLWMFIGALILSNLIAVITFMVTRDKKRIEKLLEARTE
ELHYMAMHDDLTGLLNRRSMTKVVNRFIEEDKPFALICFDIDNFKDINDTYGHPEGDEVLLHITYLVSDLLGEATPIIRL
GGDEFAVLLEIGDLQQLSHVAKKIHQVIEESPTIIPDLIIEQTISLGAVLWRGERKEVLLKLADQALYDSKDRGRNQVTI
RG

Sequences:

>Translated_482_residues
MHFVYNSNLESNRQLFSKEAERESTLLTLLIEKDIDFIGAGANFYQGGSKQDWQQFPLFANSLLSRSQSLISLQWMQKVE
EKDIEKHSKEVKKIFPSFSIYTVPQDKPKTYDYVFKNHEPIYVATDIYPRDKKNIALLGFYSAQERFQRVVDESIKVGRP
SISDKVRLLQDGLDKSTPKTGLLVYHPVFTADKKALKGIMVGVLRVTSYFDKLVESTLLGESLVVKIIDTGFDAEDDPIM
FESPQWDDFNGLRITNSINIENRIWHVEYKSKNDLSDSQQLSLLWMFIGALILSNLIAVITFMVTRDKKRIEKLLEARTE
ELHYMAMHDDLTGLLNRRSMTKVVNRFIEEDKPFALICFDIDNFKDINDTYGHPEGDEVLLHITYLVSDLLGEATPIIRL
GGDEFAVLLEIGDLQQLSHVAKKIHQVIEESPTIIPDLIIEQTISLGAVLWRGERKEVLLKLADQALYDSKDRGRNQVTI
RG
>Mature_482_residues
MHFVYNSNLESNRQLFSKEAERESTLLTLLIEKDIDFIGAGANFYQGGSKQDWQQFPLFANSLLSRSQSLISLQWMQKVE
EKDIEKHSKEVKKIFPSFSIYTVPQDKPKTYDYVFKNHEPIYVATDIYPRDKKNIALLGFYSAQERFQRVVDESIKVGRP
SISDKVRLLQDGLDKSTPKTGLLVYHPVFTADKKALKGIMVGVLRVTSYFDKLVESTLLGESLVVKIIDTGFDAEDDPIM
FESPQWDDFNGLRITNSINIENRIWHVEYKSKNDLSDSQQLSLLWMFIGALILSNLIAVITFMVTRDKKRIEKLLEARTE
ELHYMAMHDDLTGLLNRRSMTKVVNRFIEEDKPFALICFDIDNFKDINDTYGHPEGDEVLLHITYLVSDLLGEATPIIRL
GGDEFAVLLEIGDLQQLSHVAKKIHQVIEESPTIIPDLIIEQTISLGAVLWRGERKEVLLKLADQALYDSKDRGRNQVTI
RG

Specific function: Unknown

COG id: COG3614

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=33.7423312883436, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=34.1463414634146, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082007, Length=217, Percent_Identity=32.7188940092166, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=33.7078651685393, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=33.9506172839506, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788381, Length=186, Percent_Identity=30.1075268817204, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787541, Length=165, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787056, Length=155, Percent_Identity=34.1935483870968, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=30.2325581395349, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=153, Percent_Identity=28.7581699346405, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787802, Length=213, Percent_Identity=27.2300469483568, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=29.5180722891566, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=252, Percent_Identity=26.984126984127, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 55284; Mature: 55284

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50839 CHASE ; PS00136 SUBTILASE_ASP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFVYNSNLESNRQLFSKEAERESTLLTLLIEKDIDFIGAGANFYQGGSKQDWQQFPLFA
CEEEECCCCCHHHHHHHHHHHHHHHEEEEEEECCCCEEECCCHHCCCCCCCCHHHHHHHH
NSLLSRSQSLISLQWMQKVEEKDIEKHSKEVKKIFPSFSIYTVPQDKPKTYDYVFKNHEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHEECCCCC
IYVATDIYPRDKKNIALLGFYSAQERFQRVVDESIKVGRPSISDKVRLLQDGLDKSTPKT
EEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
GLLVYHPVFTADKKALKGIMVGVLRVTSYFDKLVESTLLGESLVVKIIDTGFDAEDDPIM
CEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCEE
FESPQWDDFNGLRITNSINIENRIWHVEYKSKNDLSDSQQLSLLWMFIGALILSNLIAVI
ECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFMVTRDKKRIEKLLEARTEELHYMAMHDDLTGLLNRRSMTKVVNRFIEEDKPFALICFD
HHHHHCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IDNFKDINDTYGHPEGDEVLLHITYLVSDLLGEATPIIRLGGDEFAVLLEIGDLQQLSHV
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCHHHHHHH
AKKIHQVIEESPTIIPDLIIEQTISLGAVLWRGERKEVLLKLADQALYDSKDRGRNQVTI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
RG
EC
>Mature Secondary Structure
MHFVYNSNLESNRQLFSKEAERESTLLTLLIEKDIDFIGAGANFYQGGSKQDWQQFPLFA
CEEEECCCCCHHHHHHHHHHHHHHHEEEEEEECCCCEEECCCHHCCCCCCCCHHHHHHHH
NSLLSRSQSLISLQWMQKVEEKDIEKHSKEVKKIFPSFSIYTVPQDKPKTYDYVFKNHEP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHEECCCCC
IYVATDIYPRDKKNIALLGFYSAQERFQRVVDESIKVGRPSISDKVRLLQDGLDKSTPKT
EEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
GLLVYHPVFTADKKALKGIMVGVLRVTSYFDKLVESTLLGESLVVKIIDTGFDAEDDPIM
CEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCCCEE
FESPQWDDFNGLRITNSINIENRIWHVEYKSKNDLSDSQQLSLLWMFIGALILSNLIAVI
ECCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFMVTRDKKRIEKLLEARTEELHYMAMHDDLTGLLNRRSMTKVVNRFIEEDKPFALICFD
HHHHHCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
IDNFKDINDTYGHPEGDEVLLHITYLVSDLLGEATPIIRLGGDEFAVLLEIGDLQQLSHV
CCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCHHHHHHH
AKKIHQVIEESPTIIPDLIIEQTISLGAVLWRGERKEVLLKLADQALYDSKDRGRNQVTI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCCCEEEE
RG
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]