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The map label for this gene is adhB [H]

Identifier: 209695265

GI number: 209695265

Start: 1905921

End: 1907066

Strand: Reverse

Name: adhB [H]

Synonym: VSAL_I1788

Alternate gene names: 209695265

Gene position: 1907066-1905921 (Counterclockwise)

Preceding gene: 209695266

Following gene: 209695264

Centisome position: 57.35

GC content: 43.54

Gene sequence:

>1146_bases
ATGAGTGCATTTTTTATCCCTAGCATTAATCTAATGGGTGCGGGTTGCCTTGCAGAAGCAATGGACAGCATCAAATCTCA
AGGCTACAAAAAAGCGTTAATCGTGACTGATAATGTATTAGTCGCTATCGGCATGGTAAAGCAAGTTTCTGATTTATTAG
CTGAGCGCGGTGTAGAAGTTGCGGTGTTTGACGGCACTCAGCCAAATCCAACCATTGGTAACGTAAACGCAGGTCTTAAA
ATCCTACAAGAAAATCAGTGTGACTTAGTTATATCTTTAGGTGGCGGTTCTCCACATGATTGCGCTAAAGGTATTGCTTT
AGTTGCGGCGAATGGTGGTGAAATTGCAGATTATGAAGGCGTAGATCAATCGCCAAAACCTCAAATGCCTTTAGTTGCTA
TCAATACAACCGCAGGCACTGCATCAGAAATGACCCGTTTCTGTATTATTACTGATGAAGCTCGTCACATTAAAATGGCG
ATTGTGGATAAGCACACAACGCCGTTAATGTCAGTGAACGATCCAGAGCTGATGCTTGCTAAACCGGCCTCATTAACCGC
AGCGACAGGTATGGATGCATTAACGCATGCAATTGAAGCGTATGTGTCTATTGCGGCAACACCAATCACAGACGCCGTAG
CGATTAAAGCGATGGAACTAATTCAAGCGCACTTACGCACCGCGGTAGAAGATGGTCAAAACCTTGAAGCGCGTGAGCAA
ATGGCGTACGCACAGTTTATGGCTGGCATGGCATTTAATAACGCGTCTTTAGGGTATGTTCACGCGATGGCACACCAATT
GGGTGGTTTTTATGACCTTCCACATGGCGTATGTAATGCCATTCTTCTTCCTCATGTACAAAGCTACAACGCAAAAGTAT
GTCCAGAGCGTTTAAAAGACGTGGCAAAAGCAATGGGTGTAAACGTAGAAGGTATGACGAACGAAGAGGGCGCACAAGCG
GCTCTTGATGCTATTAAGGTCTTATCAAAAGACGTAGGTATTCCTTCTGGTTTAACTGCATTAAATGCAAAAGAAGAAGA
TTTTGATACCTTGGCGGAAAATGCGCTTAAAGATGCGTGTGGATTTACTAACCCTAAACAAGCAACGCATGACGAAATTG
TGAATATTTTTAAAGCGGCAATGTAA

Upstream 100 bases:

>100_bases
ACTTGTTGCAGAAATTGTCTTAGATCAAAAAGTTATTAACCGCATCAATGTTAAAACATAACTAACGATTAAATTTATTT
AAATAAGATTGGAGTAAGTT

Downstream 100 bases:

>100_bases
GAATACCCATTTCAGTAATTATCTGTGCATTCTTACTGGTTAACTCACTTTATAGCGGCGTTAAAAATTAGGATGGTAGA
ATAACTACTTATCATAATTT

Product: alcohol dehydrogenase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSAFFIPSINLMGAGCLAEAMDSIKSQGYKKALIVTDNVLVAIGMVKQVSDLLAERGVEVAVFDGTQPNPTIGNVNAGLK
ILQENQCDLVISLGGGSPHDCAKGIALVAANGGEIADYEGVDQSPKPQMPLVAINTTAGTASEMTRFCIITDEARHIKMA
IVDKHTTPLMSVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAMELIQAHLRTAVEDGQNLEAREQ
MAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQSYNAKVCPERLKDVAKAMGVNVEGMTNEEGAQA
ALDAIKVLSKDVGIPSGLTALNAKEEDFDTLAENALKDACGFTNPKQATHDEIVNIFKAAM

Sequences:

>Translated_381_residues
MSAFFIPSINLMGAGCLAEAMDSIKSQGYKKALIVTDNVLVAIGMVKQVSDLLAERGVEVAVFDGTQPNPTIGNVNAGLK
ILQENQCDLVISLGGGSPHDCAKGIALVAANGGEIADYEGVDQSPKPQMPLVAINTTAGTASEMTRFCIITDEARHIKMA
IVDKHTTPLMSVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAMELIQAHLRTAVEDGQNLEAREQ
MAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQSYNAKVCPERLKDVAKAMGVNVEGMTNEEGAQA
ALDAIKVLSKDVGIPSGLTALNAKEEDFDTLAENALKDACGFTNPKQATHDEIVNIFKAAM
>Mature_380_residues
SAFFIPSINLMGAGCLAEAMDSIKSQGYKKALIVTDNVLVAIGMVKQVSDLLAERGVEVAVFDGTQPNPTIGNVNAGLKI
LQENQCDLVISLGGGSPHDCAKGIALVAANGGEIADYEGVDQSPKPQMPLVAINTTAGTASEMTRFCIITDEARHIKMAI
VDKHTTPLMSVNDPELMLAKPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAMELIQAHLRTAVEDGQNLEAREQM
AYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQSYNAKVCPERLKDVAKAMGVNVEGMTNEEGAQAA
LDAIKVLSKDVGIPSGLTALNAKEEDFDTLAENALKDACGFTNPKQATHDEIVNIFKAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=25.9168704156479, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI48994951, Length=380, Percent_Identity=71.0526315789474, Blast_Score=562, Evalue=1e-161,
Organism=Escherichia coli, GI1789163, Length=374, Percent_Identity=45.9893048128342, Blast_Score=331, Evalue=4e-92,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=36.3395225464191, Blast_Score=235, Evalue=3e-63,
Organism=Escherichia coli, GI1787493, Length=404, Percent_Identity=33.6633663366337, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1789386, Length=349, Percent_Identity=27.2206303724928, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=410, Percent_Identity=24.6341463414634, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321181, Length=383, Percent_Identity=55.6135770234987, Blast_Score=430, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=28.0487804878049, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40167; Mature: 40035

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFFIPSINLMGAGCLAEAMDSIKSQGYKKALIVTDNVLVAIGMVKQVSDLLAERGVEV
CCEEECCCCHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEE
AVFDGTQPNPTIGNVNAGLKILQENQCDLVISLGGGSPHDCAKGIALVAANGGEIADYEG
EEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHCCEEEEEECCCCCCCCCC
VDQSPKPQMPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLMSVNDPELMLA
CCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCCEECCCCCEEEE
KPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAMELIQAHLRTAVEDGQNLEAREQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQSYNAKVCPERLKD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHCCCCCCCHHHHHH
VAKAMGVNVEGMTNEEGAQAALDAIKVLSKDVGIPSGLTALNAKEEDFDTLAENALKDAC
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GFTNPKQATHDEIVNIFKAAM
CCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SAFFIPSINLMGAGCLAEAMDSIKSQGYKKALIVTDNVLVAIGMVKQVSDLLAERGVEV
CEEECCCCHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCEE
AVFDGTQPNPTIGNVNAGLKILQENQCDLVISLGGGSPHDCAKGIALVAANGGEIADYEG
EEECCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHHCCEEEEEECCCCCCCCCC
VDQSPKPQMPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKHTTPLMSVNDPELMLA
CCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCCCEECCCCCEEEE
KPASLTAATGMDALTHAIEAYVSIAATPITDAVAIKAMELIQAHLRTAVEDGQNLEAREQ
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
MAYAQFMAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAILLPHVQSYNAKVCPERLKD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHCCCCCCCHHHHHH
VAKAMGVNVEGMTNEEGAQAALDAIKVLSKDVGIPSGLTALNAKEEDFDTLAENALKDAC
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GFTNPKQATHDEIVNIFKAAM
CCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]