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The map label for this gene is yfjP [H]

Identifier: 209695169

GI number: 209695169

Start: 1768022

End: 1768630

Strand: Reverse

Name: yfjP [H]

Synonym: VSAL_I1673

Alternate gene names: 209695169

Gene position: 1768630-1768022 (Counterclockwise)

Preceding gene: 209695172

Following gene: 209695163

Centisome position: 53.19

GC content: 41.54

Gene sequence:

>609_bases
ATGGATGAGCAGACAATAGAGCAGGGATTAAAAGCACTCTGTCTGATAGATAAAGATCTTGAAGCCGCAGTAAAAACTCA
AGGTTACCCATCGCCAAGAGTGAACCCTCATGGATTTGAGGCTTTTTTATCTATTATCGTCAGCCAACAACTGTCAACTA
AAGTGGCGGCGGTGATAATGGGTCGTTTGGTTGCGTTATTAAAAGAGGTCACTCCAGAAAGGCTCTTGAGCATTGAAGAG
CAAAACCTTCGTGATGTTGGTTTATCTTGGCGTAAGATTGAATATGCAAAAGGGCTAGCCTTAGCCGTTCAATCGGGAAA
CCTTGATATTGATGGCTTAGAGTCATTAAGTGATGAAGATGCTATCAGTGCTATAACCAGTTTAAAGGGGTTTGGTCGTT
GGAGTGCTGAGATTTATTTGATGTTTTCATTAGGACGACAAGATATTTTTCCCGCTGATGATTTAGGGGTATTGATAGCA
TTAGGAAGACTGAAAGGACTTACTGATAAACCAACACCAAAACAAGCGAGAGAAATGGTAGGGCATTGGCAACCATGGAG
AAGTGTCGGCTCGTTATTTCTTTGGCAGTATTATCATCAAGATGCCTAA

Upstream 100 bases:

>100_bases
CATTTATCGCTTTAGGATTATCAACCATTGATGGAAGGCTATGGTAATGTATTTCTTTAAGAAAAACACAATCTAACGGC
AATGTAGGAGTAGAGTCAGT

Downstream 100 bases:

>100_bases
ATCTCCAAGTAAACAATAGGACTACTAAGTGTGGGCGTTTTGTAAGCGTGCGGGGAACTACACCTTGTCTTTTACATTCC
AAGGTAAAAGTGAATCGATA

Product: DNA repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MDEQTIEQGLKALCLIDKDLEAAVKTQGYPSPRVNPHGFEAFLSIIVSQQLSTKVAAVIMGRLVALLKEVTPERLLSIEE
QNLRDVGLSWRKIEYAKGLALAVQSGNLDIDGLESLSDEDAISAITSLKGFGRWSAEIYLMFSLGRQDIFPADDLGVLIA
LGRLKGLTDKPTPKQAREMVGHWQPWRSVGSLFLWQYYHQDA

Sequences:

>Translated_202_residues
MDEQTIEQGLKALCLIDKDLEAAVKTQGYPSPRVNPHGFEAFLSIIVSQQLSTKVAAVIMGRLVALLKEVTPERLLSIEE
QNLRDVGLSWRKIEYAKGLALAVQSGNLDIDGLESLSDEDAISAITSLKGFGRWSAEIYLMFSLGRQDIFPADDLGVLIA
LGRLKGLTDKPTPKQAREMVGHWQPWRSVGSLFLWQYYHQDA
>Mature_202_residues
MDEQTIEQGLKALCLIDKDLEAAVKTQGYPSPRVNPHGFEAFLSIIVSQQLSTKVAAVIMGRLVALLKEVTPERLLSIEE
QNLRDVGLSWRKIEYAKGLALAVQSGNLDIDGLESLSDEDAISAITSLKGFGRWSAEIYLMFSLGRQDIFPADDLGVLIA
LGRLKGLTDKPTPKQAREMVGHWQPWRSVGSLFLWQYYHQDA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=169, Percent_Identity=27.810650887574, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320990, Length=150, Percent_Identity=35.3333333333333, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 22455; Mature: 22455

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQTIEQGLKALCLIDKDLEAAVKTQGYPSPRVNPHGFEAFLSIIVSQQLSTKVAAVIM
CCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GRLVALLKEVTPERLLSIEEQNLRDVGLSWRKIEYAKGLALAVQSGNLDIDGLESLSDED
HHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCCCCCHHHCCCHH
AISAITSLKGFGRWSAEIYLMFSLGRQDIFPADDLGVLIALGRLKGLTDKPTPKQAREMV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
GHWQPWRSVGSLFLWQYYHQDA
CCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDEQTIEQGLKALCLIDKDLEAAVKTQGYPSPRVNPHGFEAFLSIIVSQQLSTKVAAVIM
CCHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GRLVALLKEVTPERLLSIEEQNLRDVGLSWRKIEYAKGLALAVQSGNLDIDGLESLSDED
HHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCCCCCHHHCCCHH
AISAITSLKGFGRWSAEIYLMFSLGRQDIFPADDLGVLIALGRLKGLTDKPTPKQAREMV
HHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
GHWQPWRSVGSLFLWQYYHQDA
CCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]