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The map label for this gene is aqpZ [H]

Identifier: 209695172

GI number: 209695172

Start: 1770234

End: 1770923

Strand: Reverse

Name: aqpZ [H]

Synonym: VSAL_I1676

Alternate gene names: 209695172

Gene position: 1770923-1770234 (Counterclockwise)

Preceding gene: 209695179

Following gene: 209695169

Centisome position: 53.26

GC content: 43.33

Gene sequence:

>690_bases
ATGAATAAATATATGGCAGAATTTATAGGCACGTTTTGGCTCGTGCTAGGTGGTTGTGGTAGTGCAGTATTGGCGGCTGG
CTTTCCAGAGCTAGGTATTGGCTTTGTCGGTGTCGCACTTGCGTTTGGTCTAACAGTATTAACGATGGCATTTGCTATTG
GACATATTTCTGGTTGCCATTTAAACCCTGCCGTTTCTATAGGCCTTTGGGTTGGCGGACGTTTTGATGCAAAAGATCTC
GTTCCTTACATTATCTCACAAGTTTTAGGCGGGATTGCTGCGGGTGGTATTTTATACTTAATCGCAAGTGGTCAAGCTGG
CTTTGATTTAGCGGGTGGTTTTGCATCAAATGGTTTTGGTGAACATTCTCCTGGTGGCTACACAATGATGTCAGCACTTA
TCATCGAAGTTGTCTTAACTGCGATGTTCCTAATTGTGATTATGGGTGCGACAGATAGCCGTGCTCCAGCAGGTTTTGCT
CCTATTGCGATTGGTTTGTGTCTAACACTTATTCACTTAATCAGTATTCCTGTAACAAACACTTCTGTTAACCCTGCGCG
TAGTACTGCTGTTGCAGTTTATGTTGGTGATTGGGCTACATCTCAACTTTGGTTGTTCTGGGTTGCTCCAATTGTAGGTG
CCATATTGGGTGCGTTAATCTACAAAGTAATCGCTAAAGAAGAAGCATAA

Upstream 100 bases:

>100_bases
TAATTTGCAAATCATAACCTATATTTATGTTGAACAAGAACTTGGTTCGAGATAAAAATTTTCATTTAAATCAAGTAATA
ATAAGGATATAGGGATAATT

Downstream 100 bases:

>100_bases
TTTAGAACGTACTTTTTAGATGTAATATGTAAAAACAAAAATGCCGATGTTTATCATCGGCATTTTTATATCTACTGCTT
ATTTTCTGCACGTTACTTTT

Product: aquaporin Z

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNKYMAEFIGTFWLVLGGCGSAVLAAGFPELGIGFVGVALAFGLTVLTMAFAIGHISGCHLNPAVSIGLWVGGRFDAKDL
VPYIISQVLGGIAAGGILYLIASGQAGFDLAGGFASNGFGEHSPGGYTMMSALIIEVVLTAMFLIVIMGATDSRAPAGFA
PIAIGLCLTLIHLISIPVTNTSVNPARSTAVAVYVGDWATSQLWLFWVAPIVGAILGALIYKVIAKEEA

Sequences:

>Translated_229_residues
MNKYMAEFIGTFWLVLGGCGSAVLAAGFPELGIGFVGVALAFGLTVLTMAFAIGHISGCHLNPAVSIGLWVGGRFDAKDL
VPYIISQVLGGIAAGGILYLIASGQAGFDLAGGFASNGFGEHSPGGYTMMSALIIEVVLTAMFLIVIMGATDSRAPAGFA
PIAIGLCLTLIHLISIPVTNTSVNPARSTAVAVYVGDWATSQLWLFWVAPIVGAILGALIYKVIAKEEA
>Mature_229_residues
MNKYMAEFIGTFWLVLGGCGSAVLAAGFPELGIGFVGVALAFGLTVLTMAFAIGHISGCHLNPAVSIGLWVGGRFDAKDL
VPYIISQVLGGIAAGGILYLIASGQAGFDLAGGFASNGFGEHSPGGYTMMSALIIEVVLTAMFLIVIMGATDSRAPAGFA
PIAIGLCLTLIHLISIPVTNTSVNPARSTAVAVYVGDWATSQLWLFWVAPIVGAILGALIYKVIAKEEA

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4502179, Length=221, Percent_Identity=35.7466063348416, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI4502183, Length=223, Percent_Identity=37.6681614349776, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI37694062, Length=227, Percent_Identity=37.0044052863436, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4502181, Length=226, Percent_Identity=33.6283185840708, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI4755125, Length=226, Percent_Identity=33.6283185840708, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI6912506, Length=221, Percent_Identity=33.0316742081448, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI86792455, Length=219, Percent_Identity=30.1369863013699, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI157266307, Length=245, Percent_Identity=30.2040816326531, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI45446752, Length=204, Percent_Identity=31.8627450980392, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI22538420, Length=242, Percent_Identity=27.6859504132231, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4826645, Length=249, Percent_Identity=26.1044176706827, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI297307120, Length=92, Percent_Identity=40.2173913043478, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI4502187, Length=244, Percent_Identity=27.0491803278689, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787101, Length=229, Percent_Identity=73.7991266375546, Blast_Score=314, Evalue=3e-87,
Organism=Escherichia coli, GI1790362, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71993722, Length=235, Percent_Identity=30.6382978723404, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71992966, Length=241, Percent_Identity=27.8008298755187, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558372, Length=243, Percent_Identity=27.1604938271605, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24652747, Length=224, Percent_Identity=35.2678571428571, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI45551084, Length=224, Percent_Identity=35.2678571428571, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24652751, Length=221, Percent_Identity=33.0316742081448, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19922038, Length=221, Percent_Identity=33.0316742081448, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45550503, Length=227, Percent_Identity=28.1938325991189, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24762346, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24762348, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130305, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24762344, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17136672, Length=227, Percent_Identity=26.431718061674, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24762342, Length=195, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 23537; Mature: 23537

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYMAEFIGTFWLVLGGCGSAVLAAGFPELGIGFVGVALAFGLTVLTMAFAIGHISGCH
CCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPAVSIGLWVGGRFDAKDLVPYIISQVLGGIAAGGILYLIASGQAGFDLAGGFASNGFG
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCCCCCCCC
EHSPGGYTMMSALIIEVVLTAMFLIVIMGATDSRAPAGFAPIAIGLCLTLIHLISIPVTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
TSVNPARSTAVAVYVGDWATSQLWLFWVAPIVGAILGALIYKVIAKEEA
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKYMAEFIGTFWLVLGGCGSAVLAAGFPELGIGFVGVALAFGLTVLTMAFAIGHISGCH
CCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LNPAVSIGLWVGGRFDAKDLVPYIISQVLGGIAAGGILYLIASGQAGFDLAGGFASNGFG
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHEEEEECCCCCCCCCCCCCCCCCC
EHSPGGYTMMSALIIEVVLTAMFLIVIMGATDSRAPAGFAPIAIGLCLTLIHLISIPVTN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
TSVNPARSTAVAVYVGDWATSQLWLFWVAPIVGAILGALIYKVIAKEEA
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]