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The map label for this gene is luxQ [H]

Identifier: 209695063

GI number: 209695063

Start: 1671140

End: 1673233

Strand: Reverse

Name: luxQ [H]

Synonym: VSAL_I1560

Alternate gene names: 209695063

Gene position: 1673233-1671140 (Counterclockwise)

Preceding gene: 209695064

Following gene: 209695062

Centisome position: 50.32

GC content: 33.57

Gene sequence:

>2094_bases
GTGCATAAAGTGAAGGACTACACGGAAAAAGAACAGCTTCAGGAAGCATTATTAGAATTAAAACGGAGTAAAGAAAGAGA
GGCGCATTTATACAAAGAAAATGAAGCTATTTTAAGTGGGTTATCTGCTATCTCTGATGCTCAAACCAAGCAGGATATTT
TTAATGAATTACTTGATGTCGTTAAAAAATTTGTTCCCTTCGACAACGCCATCGTTTTATCTTCTTCTTCTGAAGTTGAA
CAATTTACAGTTTTAGCCTCGACTAATGAGCGGTTTAATTCATTAGCATGGGAATATAACGATTTATTTGATCGCGCTTG
TCATAATGAGAGTATTGTCCTTTTTAGTCCTTGTGATAATCCACACTTTTCATTTATCCCAAAACACATCCAATCTGATT
TTGAATCTATATCTTTAACTGGTATTAAATCCCATTCTGGTTATGCCATTATTATGCTAATGAGTTCTACATTTGGCATG
TATTCATCTTCGACTAAAGAAAAAATGCAGCGATTCATTCCTTTAGTTGAGCGTGCGATTATAGATATTGATTACAAAGA
CAGATTGCATTCATTAGTTAATATTAAAACCAAAGAATTGCATTTAAGTAATGATCGTTTTAAAGACTTTGCAGAATCTG
CGGGGGATTGGTTTTGGGAGACTGATTTAGGTTTTAATTTTACTTATATTTCAGACTCTACCATTAAAACCATTGTTATC
ACAGATCGTAATTTATTAACTCTAATCAATGATAACCCAACAACATCTCAAATTTTATCTTCAAAATCAATGGTTAAGTC
ATTTGATGAACTAGAATGGTGGCCATCTATATTTAAGCAACAGGTTTGCATGAGCATTAGTGGTACTCCTTATTTTGATG
ACGCTGGACAACTCATTGGTTACAGAGGAACAGCTAAAGATATATCAATAAGAAAAAAACGGCTTCAACAAATACAAAAA
GCGAAACAAGAAGCTGAAACTGCCAACAAAGCTAAATCTCAATTTTTAGCTATGATGAGCCATGAAATAAGAACACCATT
GAATGCAATCCTTGGTATGGTTGATGTATTTAACGAAAGTCTTCTATCGAAAGAACAATACGAATGGCTTGATCAGATGG
AGGTTTCAGCACAACTTCTTCTGGCTATTATTAGTGACGTTCTTGATATATCTAGGATAGAAGCTGGGACCTTTGTTTTA
GATGAACAACCAATAGATTTATTAGAAACTATTATTAATTCAACGAATTACTTCAAGGAAAAGAGTAAAGATAAAGGAAT
AAATTTAACTGTTACGGTGTCACATAGTGTGCCTAACTACGTAATAGCAGATGCAGCAAGAATCATGCAGATCATATTTA
ACTTAGTTGGTAACGCTGTTAAATTCACCAAAAAAGGATCTATATGGATAAATATCACACAAACAGAGTGTAATTCAACC
AAGATAGCCATCACGGATACAGGAATTGGTATATCCAAAGATGTATTAAATAACTTGTTCCAGCCATTCGTACAAGCAGA
CAGCTCAATTACTCGTCAATTCGGTGGTTCTGGACTTGGTTTATCTATAATAAAACGACTTACTGAACTAATGAATGGTG
TTATTTCGGTTAAAAGTGTCATTAATGAAGGCAGTACTTTTACCGTAACATTACCATTTAAAGAAACGAAAGAATGTCCA
AAACGTATTACTTTAAATAATAATGACGTGACTGATAAATCAACTCGAACACTGAATATTCTTATTGCTGAAGACAGCAA
AGCAAATCAAGCGGTCATTCAATTACTTCTTGAAGGTCAAGGACATCAAATAACATTAGTCGATAATGGATGCATGGCGG
TTGAAGCGATAGAAAACAAAAATCAGAACTTCGACCTAATTTTAATGGATGTATCTATGCCAATAAAAGATGGCATCAGT
GCGACAAAAGAAATTAGAGCTAAAGGTTATAATTTACCAATCTTAGCATTAACAGCACATGCTATGAATGAAGAAAAGAA
AACATGTATAGATGCTGGTATGAATGATTTCATTTCGAAACCAGTACGAGCACAAGAATTAAAATTGATCTTAGATTCAT
TAAAGCTTGGCTAA

Upstream 100 bases:

>100_bases
TTATATTTGTCCATTTACTTTTGGCGAACAAGGTCGATTTACTGGTGGAGAAAATGCCCACGGTAATTTGATGGTTTCAG
CTGTTTTATTCCATTATTAG

Downstream 100 bases:

>100_bases
TAATCACTAGATAAATACGAAGTATTATTTAATGATTATTAGCTATTTTATGGTAAATACGATTATAGTTAAATAGCTTC
GTTATGAACATTGGGATGGT

Product: response regulator, histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 697

Protein sequence:

>697_residues
MHKVKDYTEKEQLQEALLELKRSKEREAHLYKENEAILSGLSAISDAQTKQDIFNELLDVVKKFVPFDNAIVLSSSSEVE
QFTVLASTNERFNSLAWEYNDLFDRACHNESIVLFSPCDNPHFSFIPKHIQSDFESISLTGIKSHSGYAIIMLMSSTFGM
YSSSTKEKMQRFIPLVERAIIDIDYKDRLHSLVNIKTKELHLSNDRFKDFAESAGDWFWETDLGFNFTYISDSTIKTIVI
TDRNLLTLINDNPTTSQILSSKSMVKSFDELEWWPSIFKQQVCMSISGTPYFDDAGQLIGYRGTAKDISIRKKRLQQIQK
AKQEAETANKAKSQFLAMMSHEIRTPLNAILGMVDVFNESLLSKEQYEWLDQMEVSAQLLLAIISDVLDISRIEAGTFVL
DEQPIDLLETIINSTNYFKEKSKDKGINLTVTVSHSVPNYVIADAARIMQIIFNLVGNAVKFTKKGSIWINITQTECNST
KIAITDTGIGISKDVLNNLFQPFVQADSSITRQFGGSGLGLSIIKRLTELMNGVISVKSVINEGSTFTVTLPFKETKECP
KRITLNNNDVTDKSTRTLNILIAEDSKANQAVIQLLLEGQGHQITLVDNGCMAVEAIENKNQNFDLILMDVSMPIKDGIS
ATKEIRAKGYNLPILALTAHAMNEEKKTCIDAGMNDFISKPVRAQELKLILDSLKLG

Sequences:

>Translated_697_residues
MHKVKDYTEKEQLQEALLELKRSKEREAHLYKENEAILSGLSAISDAQTKQDIFNELLDVVKKFVPFDNAIVLSSSSEVE
QFTVLASTNERFNSLAWEYNDLFDRACHNESIVLFSPCDNPHFSFIPKHIQSDFESISLTGIKSHSGYAIIMLMSSTFGM
YSSSTKEKMQRFIPLVERAIIDIDYKDRLHSLVNIKTKELHLSNDRFKDFAESAGDWFWETDLGFNFTYISDSTIKTIVI
TDRNLLTLINDNPTTSQILSSKSMVKSFDELEWWPSIFKQQVCMSISGTPYFDDAGQLIGYRGTAKDISIRKKRLQQIQK
AKQEAETANKAKSQFLAMMSHEIRTPLNAILGMVDVFNESLLSKEQYEWLDQMEVSAQLLLAIISDVLDISRIEAGTFVL
DEQPIDLLETIINSTNYFKEKSKDKGINLTVTVSHSVPNYVIADAARIMQIIFNLVGNAVKFTKKGSIWINITQTECNST
KIAITDTGIGISKDVLNNLFQPFVQADSSITRQFGGSGLGLSIIKRLTELMNGVISVKSVINEGSTFTVTLPFKETKECP
KRITLNNNDVTDKSTRTLNILIAEDSKANQAVIQLLLEGQGHQITLVDNGCMAVEAIENKNQNFDLILMDVSMPIKDGIS
ATKEIRAKGYNLPILALTAHAMNEEKKTCIDAGMNDFISKPVRAQELKLILDSLKLG
>Mature_697_residues
MHKVKDYTEKEQLQEALLELKRSKEREAHLYKENEAILSGLSAISDAQTKQDIFNELLDVVKKFVPFDNAIVLSSSSEVE
QFTVLASTNERFNSLAWEYNDLFDRACHNESIVLFSPCDNPHFSFIPKHIQSDFESISLTGIKSHSGYAIIMLMSSTFGM
YSSSTKEKMQRFIPLVERAIIDIDYKDRLHSLVNIKTKELHLSNDRFKDFAESAGDWFWETDLGFNFTYISDSTIKTIVI
TDRNLLTLINDNPTTSQILSSKSMVKSFDELEWWPSIFKQQVCMSISGTPYFDDAGQLIGYRGTAKDISIRKKRLQQIQK
AKQEAETANKAKSQFLAMMSHEIRTPLNAILGMVDVFNESLLSKEQYEWLDQMEVSAQLLLAIISDVLDISRIEAGTFVL
DEQPIDLLETIINSTNYFKEKSKDKGINLTVTVSHSVPNYVIADAARIMQIIFNLVGNAVKFTKKGSIWINITQTECNST
KIAITDTGIGISKDVLNNLFQPFVQADSSITRQFGGSGLGLSIIKRLTELMNGVISVKSVINEGSTFTVTLPFKETKECP
KRITLNNNDVTDKSTRTLNILIAEDSKANQAVIQLLLEGQGHQITLVDNGCMAVEAIENKNQNFDLILMDVSMPIKDGIS
ATKEIRAKGYNLPILALTAHAMNEEKKTCIDAGMNDFISKPVRAQELKLILDSLKLG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=416, Percent_Identity=31.9711538461538, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1788713, Length=415, Percent_Identity=32.0481927710843, Blast_Score=198, Evalue=1e-51,
Organism=Escherichia coli, GI1789149, Length=385, Percent_Identity=34.8051948051948, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI87081816, Length=388, Percent_Identity=33.5051546391753, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=36.8421052631579, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=28.1385281385281, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=29.5275590551181, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=25.5813953488372, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=25.2212389380531, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=24.7826086956522, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=280, Percent_Identity=24.6428571428571, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=25.6637168141593, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=105, Percent_Identity=34.2857142857143, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082128, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=111, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=27.7533039647577, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790551, Length=202, Percent_Identity=29.2079207920792, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=24.1666666666667, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=24.3362831858407, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=42.4, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6322000, Length=125, Percent_Identity=32.8, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78314; Mature: 78314

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKVKDYTEKEQLQEALLELKRSKEREAHLYKENEAILSGLSAISDAQTKQDIFNELLDV
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKFVPFDNAIVLSSSSEVEQFTVLASTNERFNSLAWEYNDLFDRACHNESIVLFSPCDN
HHHHCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PHFSFIPKHIQSDFESISLTGIKSHSGYAIIMLMSSTFGMYSSSTKEKMQRFIPLVERAI
CCCHHCHHHHHCCHHHEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IDIDYKDRLHSLVNIKTKELHLSNDRFKDFAESAGDWFWETDLGFNFTYISDSTIKTIVI
CCCCHHHHHHHHHCCEEHEEECCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCEEEEEE
TDRNLLTLINDNPTTSQILSSKSMVKSFDELEWWPSIFKQQVCMSISGTPYFDDAGQLIG
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
YRGTAKDISIRKKRLQQIQKAKQEAETANKAKSQFLAMMSHEIRTPLNAILGMVDVFNES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LLSKEQYEWLDQMEVSAQLLLAIISDVLDISRIEAGTFVLDEQPIDLLETIINSTNYFKE
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHH
KSKDKGINLTVTVSHSVPNYVIADAARIMQIIFNLVGNAVKFTKKGSIWINITQTECNST
HCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCE
KIAITDTGIGISKDVLNNLFQPFVQADSSITRQFGGSGLGLSIIKRLTELMNGVISVKSV
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INEGSTFTVTLPFKETKECPKRITLNNNDVTDKSTRTLNILIAEDSKANQAVIQLLLEGQ
HCCCCEEEEEECCHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCC
GHQITLVDNGCMAVEAIENKNQNFDLILMDVSMPIKDGISATKEIRAKGYNLPILALTAH
CCEEEEEECCCEEEEEHHCCCCCCEEEEEEECCCHHHCCHHHHHHHHCCCCCCEEEEEHH
AMNEEKKTCIDAGMNDFISKPVRAQELKLILDSLKLG
HHCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKVKDYTEKEQLQEALLELKRSKEREAHLYKENEAILSGLSAISDAQTKQDIFNELLDV
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKKFVPFDNAIVLSSSSEVEQFTVLASTNERFNSLAWEYNDLFDRACHNESIVLFSPCDN
HHHHCCCCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PHFSFIPKHIQSDFESISLTGIKSHSGYAIIMLMSSTFGMYSSSTKEKMQRFIPLVERAI
CCCHHCHHHHHCCHHHEEEEEEECCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
IDIDYKDRLHSLVNIKTKELHLSNDRFKDFAESAGDWFWETDLGFNFTYISDSTIKTIVI
CCCCHHHHHHHHHCCEEHEEECCCHHHHHHHHHCCCCEEEECCCEEEEEECCCCEEEEEE
TDRNLLTLINDNPTTSQILSSKSMVKSFDELEWWPSIFKQQVCMSISGTPYFDDAGQLIG
ECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
YRGTAKDISIRKKRLQQIQKAKQEAETANKAKSQFLAMMSHEIRTPLNAILGMVDVFNES
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LLSKEQYEWLDQMEVSAQLLLAIISDVLDISRIEAGTFVLDEQPIDLLETIINSTNYFKE
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCHHHHHH
KSKDKGINLTVTVSHSVPNYVIADAARIMQIIFNLVGNAVKFTKKGSIWINITQTECNST
HCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCCCCE
KIAITDTGIGISKDVLNNLFQPFVQADSSITRQFGGSGLGLSIIKRLTELMNGVISVKSV
EEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
INEGSTFTVTLPFKETKECPKRITLNNNDVTDKSTRTLNILIAEDSKANQAVIQLLLEGQ
HCCCCEEEEEECCHHHHCCCCEEECCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCC
GHQITLVDNGCMAVEAIENKNQNFDLILMDVSMPIKDGISATKEIRAKGYNLPILALTAH
CCEEEEEECCCEEEEEHHCCCCCCEEEEEEECCCHHHCCHHHHHHHHCCCCCCEEEEEHH
AMNEEKKTCIDAGMNDFISKPVRAQELKLILDSLKLG
HHCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA