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The map label for this gene is rbsK [H]

Identifier: 209694895

GI number: 209694895

Start: 1489002

End: 1489919

Strand: Reverse

Name: rbsK [H]

Synonym: VSAL_I1368

Alternate gene names: 209694895

Gene position: 1489919-1489002 (Counterclockwise)

Preceding gene: 209694896

Following gene: 209694894

Centisome position: 44.81

GC content: 45.32

Gene sequence:

>918_bases
ATGAATAAATTAGTTGTTTTAGGTAGCGTAAATGCAGATCACGTTCTACAAGTGGCTTCTTTCCCTCGTCCGGGCGAGAC
GTTACACGGTCACAGCTATTCCGTTATTCCTGGTGGTAAAGGCGCAAACCAAGCGGTTGCTGCCGCGCGATTAGGCGCAG
ATGTTGCTTTTATTGCCAGTGTTGGTGATGACAATTTTGGTCAACAAATGATTGAAGCATTCAAGTTTGATGGCATTAAT
ACCGAAGCGGTAATGATCGAAGAGAACACCCCAACAGGTATCGCGATGATCCAAGTCGCAGCAACGGGCGAAAACAGCAT
TTGTATTTCAGCAGAAGCAAACGCACGTTTAACCGCAGAACGCATTGCACCTCATCATGGTTTAATTGAAGCGGCTGATA
CCTTATTAATGCAACTTGAAACCCCTATTGAAACCATCGAAAAAGCAGCACAAATTGCAAAAGCGGCCGGAACGAAAGTC
GTATTAAACCCAGCCCCTGCTCAGCAATTAAGTGATGACTTATTACAACTTGTTGATATGATTACGCCAAATGAAACTGA
AGCCGAATTATTAACAGGCATTGAAGTAACGGATATGGCAAGCGCACAACGCGCAGCAGATGCGCTTCATGCAAAAGGCA
TTGAAACCGTGATGATCACCCTAGGTAGCAAAGGTGTGTGGATCAGTAAAAATGGCAAAGGCCGTCAAGTGGAAGGCTTT
AGAGTACAAGCTACCGACACCACAGGCGCAGGCGATACCTTCAATGGTGCATTTTTAACTGGCCTACAGTCTGGTCGTAA
ATTGGATGATGCGATTAAATTCGCTCACGCGGCAGCGGCAATTTCAGTAACACGAATGGGTGCTCAAACCTCTATTCCTT
CTATCACCGAAGTAGAGCGTTTTCTATTAGAGCATTGA

Upstream 100 bases:

>100_bases
AGAAAATGTATCGCTAAATGACAGAGTCTTCTCACCCATTTATCCATACGTTTTAAGGCCAATTTTCCGGCAATTTTAAA
ATAAGAAACAAAGGCACATT

Downstream 100 bases:

>100_bases
GCATTACTCTCTATTTCAGTGCCTTTGACTGCCATTCATAACGCAGTCAAAGACACAAACAAAGGATTGGATTTTATGGC
AACGATCAAAGATGTAGCCA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADVAFIASVGDDNFGQQMIEAFKFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAERIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAQQLSDDLLQLVDMITPNETEAELLTGIEVTDMASAQRAADALHAKGIETVMITLGSKGVWISKNGKGRQVEGF
RVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH

Sequences:

>Translated_305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADVAFIASVGDDNFGQQMIEAFKFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAERIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAQQLSDDLLQLVDMITPNETEAELLTGIEVTDMASAQRAADALHAKGIETVMITLGSKGVWISKNGKGRQVEGF
RVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH
>Mature_305_residues
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADVAFIASVGDDNFGQQMIEAFKFDGIN
TEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAERIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKV
VLNPAPAQQLSDDLLQLVDMITPNETEAELLTGIEVTDMASAQRAADALHAKGIETVMITLGSKGVWISKNGKGRQVEGF
RVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVERFLLEH

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=39.041095890411, Blast_Score=176, Evalue=3e-44,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=55.8528428093645, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=30.3630363036304, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081971, Length=306, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788491, Length=294, Percent_Identity=24.1496598639456, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788484, Length=282, Percent_Identity=24.468085106383, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082281, Length=274, Percent_Identity=25.1824817518248, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=38.8704318936877, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319884, Length=332, Percent_Identity=28.3132530120482, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322565, Length=290, Percent_Identity=28.6206896551724, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20128807, Length=303, Percent_Identity=37.953795379538, Blast_Score=157, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24583886, Length=298, Percent_Identity=33.2214765100671, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31964; Mature: 31964

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADVAFIAS
CCCEEEEECCCHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNFGQQMIEAFKFDGINTEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAE
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCEEEHH
RIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKVVLNPAPAQQLSDDLLQLVDM
HCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
ITPNETEAELLTGIEVTDMASAQRAADALHAKGIETVMITLGSKGVWISKNGKGRQVEGF
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
RVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVER
EEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLLEH
HHHCC
>Mature Secondary Structure
MNKLVVLGSVNADHVLQVASFPRPGETLHGHSYSVIPGGKGANQAVAAARLGADVAFIAS
CCCEEEEECCCHHHEEEECCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNFGQQMIEAFKFDGINTEAVMIEENTPTGIAMIQVAATGENSICISAEANARLTAE
CCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCEEEEECCCCEEEHH
RIAPHHGLIEAADTLLMQLETPIETIEKAAQIAKAAGTKVVLNPAPAQQLSDDLLQLVDM
HCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
ITPNETEAELLTGIEVTDMASAQRAADALHAKGIETVMITLGSKGVWISKNGKGRQVEGF
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCEECCE
RVQATDTTGAGDTFNGAFLTGLQSGRKLDDAIKFAHAAAAISVTRMGAQTSIPSITEVER
EEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLLEH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]