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The map label for this gene is betT [C]

Identifier: 209694817

GI number: 209694817

Start: 1392050

End: 1393654

Strand: Direct

Name: betT [C]

Synonym: VSAL_I1282

Alternate gene names: 209694817

Gene position: 1392050-1393654 (Clockwise)

Preceding gene: 209694815

Following gene: 209694818

Centisome position: 41.86

GC content: 43.36

Gene sequence:

>1605_bases
ATGGGTTTTAAATCAGAAAAGTACAGTATTGAATCGACGGATTATGAAGTCGGTCAAGATAACATCAGTAAATGGGGCAT
GGATGTCCACAACACCGTTTTTGTAGCCTCAGTCGGCTTATCTCTTCTCTTCATTATCACTCTTCTCGCATTACCTCCCG
CAGACGCAAAAGCAGCCATTGATTCACTTAAAGGTTCTGTGTTGTCAAATTTTGACTTCCTCTTTATGTGGGGCGCTAAC
ATCTTATTAATCTTTGCCATTATTTTAGCATTTTCGCCTTTGGGTAAAATTCGCTTAGGTGGTGACGACGCGAAACCAGA
TTATTCTAAAGCCTCTTGGATCTCGATGTTATTCGCTGCCGGTATGGGTATTGGGCTTATCTTCTGGGGTGTTGCAGAGC
CAACCGCGTTCTTTACCAACTGGTTTGGAACCCCGCTTAATGTAGAACCTTTTACAGAAGCAGGGCGTGAACTTGCTCTG
GGGGCAACGGTCTTCCACTGGGGCTTACACGCATGGGCTATCTATGGCATGACAGCACTTTGTCTTGCTTATTTTGTTTA
CAATAAAGGGTTGCCACTTTCAATGCGCTCGGTATTTTACCCATTATTGGGTGATCGAGTTTGGGGGCGAACAGGTGATG
TGATTGATATCTTAACCGTATTGGTTACCTTGTTTGGCCTAGCGACTTCCCTTGGTTTAGGAGGCACACAAGCGGCTAGT
GGTATCAGCCATGTTTTCGGAATAGACAATAATATCTATCTTCAACAAGCCGTTATCGTATTGATCATGGGTCTGGCGAT
CATTTCTGTTCTACGTGGTATGGATGGTGGCGTTAAGTTTCTTAGTAACCTGAATATGGTTATTGCGTTTGTCTTCCTTG
GCCTTATTGCTGTTTTGAATTTCACTACCGTATTGGATTCTTTGGTTACGGCTCTAACGGGTTATGTGAAAAATATTATT
CCATTGAGTCAAACCTCGGGTCGTGAAGATACAGCGTGGTTGCACGGTTGGACTGTGTTCTATTGGGCGTGGTGGGTTGC
GTATGCACCTTTCTTTGGTATGTTTGTTGCTCGTATCTCTAGAGGACGTACCGTTCGTGAATTCCTTCTTTGCGTAATGC
TTATTCCTACAATGGTAACCACGGCGTGGATGTCTATCTTCGGCGGTGTTGCGATTCAACAAGTAATAGATAAAGTTGGA
TTATTGGGCGCTCAACAAGGTATTAGCGATGTTTCTCTAAGCTTGTTCCATATGTTAGACGCTTACCCATTTGGGGATAT
TCTATCCTTTATTGCCGTGGCACTGATTATCGTTTTCTTTGTGACAACGTTGGACTCAGGCTCTATCGTTATTGATGGCA
TGACCGCCGGTGGTAAGTTAGAAGTACCCGTTAAACAGAAAGTAGTTTGGGCAGTTATCTCCGGTGCTATCGCAATGGTT
ATGTTGTGGATTGGTGGTACTCAATCTATTGAATCTCTGCAATCAATTACCATTATTGCTGCAATGCCGTTTACAATTAT
TCTCTTGCTAGGCAGTGTGAGTCTACTTAAAGGACTATTGACGGAAGTTGATAAACCAAAGGTAGCGACTAAACGAGTTA
ACTAG

Upstream 100 bases:

>100_bases
TTATATGGTATCGCTACTCAATCAAATAGTAATTGGATAAGGAGTTGTCCTTATATTCGTCTAGCTGTTCGCTTAGCCGG
ATATGTGAACATTATCGTTT

Downstream 100 bases:

>100_bases
TTAGGTTAGTTTGTAGCTAGATTAAGAGCTAAAGTTACAATTAGATCTACAATCAAACTCTCTGGTACTTTTTGCTGGGG
AGTTTTTTATGCAATAACAA

Product: transporter BCCT family

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MGFKSEKYSIESTDYEVGQDNISKWGMDVHNTVFVASVGLSLLFIITLLALPPADAKAAIDSLKGSVLSNFDFLFMWGAN
ILLIFAIILAFSPLGKIRLGGDDAKPDYSKASWISMLFAAGMGIGLIFWGVAEPTAFFTNWFGTPLNVEPFTEAGRELAL
GATVFHWGLHAWAIYGMTALCLAYFVYNKGLPLSMRSVFYPLLGDRVWGRTGDVIDILTVLVTLFGLATSLGLGGTQAAS
GISHVFGIDNNIYLQQAVIVLIMGLAIISVLRGMDGGVKFLSNLNMVIAFVFLGLIAVLNFTTVLDSLVTALTGYVKNII
PLSQTSGREDTAWLHGWTVFYWAWWVAYAPFFGMFVARISRGRTVREFLLCVMLIPTMVTTAWMSIFGGVAIQQVIDKVG
LLGAQQGISDVSLSLFHMLDAYPFGDILSFIAVALIIVFFVTTLDSGSIVIDGMTAGGKLEVPVKQKVVWAVISGAIAMV
MLWIGGTQSIESLQSITIIAAMPFTIILLLGSVSLLKGLLTEVDKPKVATKRVN

Sequences:

>Translated_534_residues
MGFKSEKYSIESTDYEVGQDNISKWGMDVHNTVFVASVGLSLLFIITLLALPPADAKAAIDSLKGSVLSNFDFLFMWGAN
ILLIFAIILAFSPLGKIRLGGDDAKPDYSKASWISMLFAAGMGIGLIFWGVAEPTAFFTNWFGTPLNVEPFTEAGRELAL
GATVFHWGLHAWAIYGMTALCLAYFVYNKGLPLSMRSVFYPLLGDRVWGRTGDVIDILTVLVTLFGLATSLGLGGTQAAS
GISHVFGIDNNIYLQQAVIVLIMGLAIISVLRGMDGGVKFLSNLNMVIAFVFLGLIAVLNFTTVLDSLVTALTGYVKNII
PLSQTSGREDTAWLHGWTVFYWAWWVAYAPFFGMFVARISRGRTVREFLLCVMLIPTMVTTAWMSIFGGVAIQQVIDKVG
LLGAQQGISDVSLSLFHMLDAYPFGDILSFIAVALIIVFFVTTLDSGSIVIDGMTAGGKLEVPVKQKVVWAVISGAIAMV
MLWIGGTQSIESLQSITIIAAMPFTIILLLGSVSLLKGLLTEVDKPKVATKRVN
>Mature_533_residues
GFKSEKYSIESTDYEVGQDNISKWGMDVHNTVFVASVGLSLLFIITLLALPPADAKAAIDSLKGSVLSNFDFLFMWGANI
LLIFAIILAFSPLGKIRLGGDDAKPDYSKASWISMLFAAGMGIGLIFWGVAEPTAFFTNWFGTPLNVEPFTEAGRELALG
ATVFHWGLHAWAIYGMTALCLAYFVYNKGLPLSMRSVFYPLLGDRVWGRTGDVIDILTVLVTLFGLATSLGLGGTQAASG
ISHVFGIDNNIYLQQAVIVLIMGLAIISVLRGMDGGVKFLSNLNMVIAFVFLGLIAVLNFTTVLDSLVTALTGYVKNIIP
LSQTSGREDTAWLHGWTVFYWAWWVAYAPFFGMFVARISRGRTVREFLLCVMLIPTMVTTAWMSIFGGVAIQQVIDKVGL
LGAQQGISDVSLSLFHMLDAYPFGDILSFIAVALIIVFFVTTLDSGSIVIDGMTAGGKLEVPVKQKVVWAVISGAIAMVM
LWIGGTQSIESLQSITIIAAMPFTIILLLGSVSLLKGLLTEVDKPKVATKRVN

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=518, Percent_Identity=34.7490347490347, Blast_Score=288, Evalue=9e-79,
Organism=Escherichia coli, GI1788102, Length=440, Percent_Identity=29.7727272727273, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1786224, Length=480, Percent_Identity=27.9166666666667, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 57788; Mature: 57657

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKSEKYSIESTDYEVGQDNISKWGMDVHNTVFVASVGLSLLFIITLLALPPADAKAAI
CCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DSLKGSVLSNFDFLFMWGANILLIFAIILAFSPLGKIRLGGDDAKPDYSKASWISMLFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHH
GMGIGLIFWGVAEPTAFFTNWFGTPLNVEPFTEAGRELALGATVFHWGLHAWAIYGMTAL
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
CLAYFVYNKGLPLSMRSVFYPLLGDRVWGRTGDVIDILTVLVTLFGLATSLGLGGTQAAS
HHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
GISHVFGIDNNIYLQQAVIVLIMGLAIISVLRGMDGGVKFLSNLNMVIAFVFLGLIAVLN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FTTVLDSLVTALTGYVKNIIPLSQTSGREDTAWLHGWTVFYWAWWVAYAPFFGMFVARIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGRTVREFLLCVMLIPTMVTTAWMSIFGGVAIQQVIDKVGLLGAQQGISDVSLSLFHMLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AYPFGDILSFIAVALIIVFFVTTLDSGSIVIDGMTAGGKLEVPVKQKVVWAVISGAIAMV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHH
MLWIGGTQSIESLQSITIIAAMPFTIILLLGSVSLLKGLLTEVDKPKVATKRVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC
>Mature Secondary Structure 
GFKSEKYSIESTDYEVGQDNISKWGMDVHNTVFVASVGLSLLFIITLLALPPADAKAAI
CCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
DSLKGSVLSNFDFLFMWGANILLIFAIILAFSPLGKIRLGGDDAKPDYSKASWISMLFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHH
GMGIGLIFWGVAEPTAFFTNWFGTPLNVEPFTEAGRELALGATVFHWGLHAWAIYGMTAL
CCHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
CLAYFVYNKGLPLSMRSVFYPLLGDRVWGRTGDVIDILTVLVTLFGLATSLGLGGTQAAS
HHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
GISHVFGIDNNIYLQQAVIVLIMGLAIISVLRGMDGGVKFLSNLNMVIAFVFLGLIAVLN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FTTVLDSLVTALTGYVKNIIPLSQTSGREDTAWLHGWTVFYWAWWVAYAPFFGMFVARIS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGRTVREFLLCVMLIPTMVTTAWMSIFGGVAIQQVIDKVGLLGAQQGISDVSLSLFHMLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AYPFGDILSFIAVALIIVFFVTTLDSGSIVIDGMTAGGKLEVPVKQKVVWAVISGAIAMV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHHH
MLWIGGTQSIESLQSITIIAAMPFTIILLLGSVSLLKGLLTEVDKPKVATKRVN
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]