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The map label for this gene is murR [H]

Identifier: 209694800

GI number: 209694800

Start: 1368340

End: 1369143

Strand: Reverse

Name: murR [H]

Synonym: VSAL_I1259

Alternate gene names: 209694800

Gene position: 1369143-1368340 (Counterclockwise)

Preceding gene: 209694804

Following gene: 209694794

Centisome position: 41.18

GC content: 37.56

Gene sequence:

>804_bases
ATGAGTATTTTAGAAAAGATACAAAATCAGAGAAGCAATTTGTCAGCCAATGGCATTAAAATTTTAGATTTTATACTAGA
ACAGCCTGCGGCAATCGGTGCCTACTCTAGCCAAGAATTGGCAAATAGAGTTCAAGTTTCTCAATCTAGCATCATTAAGC
TAACGCAAAAATTGGGCTTTAAAGGATTCACTGCTTTTAAATTGGCCATAATTGAAGACATAGGAAGAAAGCACGCCATC
CTCGAACCAGAAAAGCCAATCCACAATAAAATCCACAGTGATGATTCTTCATTAACAATGGCTCAAAAACTGGTTCAAGA
AAAACACCACGCCTTAGTTGCTACCACCAACGCCATTGATTACCAAGAGTTTGAACACATTATCTCGTTATTAAACAATG
CTAACCGAATTCAAATTATTGGTATTGGAGGATCCGCATTAACCGCAAAAGATCTGTCCTTTAAATTACTAAAGATTGGA
ATGACAGCGTTATCAGAACAAGACAGTCATGTCCAAATCGCTACCGCGAATACGCTATCAAACACAGATGTACAAATGGC
AATAGAAAAAGGAGCGACGGTTATTGCCCTTACCTCTACGAAGAAAAGTCCATTAAGGAAAGTCGCAAGCTATTGTATTG
ATACCATTGCAGATGAACGTCAGTTTCGCAGTTCATCCATTTCATCTCGTACGGCACAAAACGTCATTACCGATTTAATT
TTTATGACCTTATTTCAATTAAGAAGTGACAGTGCCAAATTGCTTATCGATAAAATCTCATCGACTATCGACAGCATTAG
ATAA

Upstream 100 bases:

>100_bases
CAGAAACAAACCATTAATTTTCAATAAGATAAAAACAATAAACCAATCAAGAATAATAAGAGTAAATTTGGAATAATTAA
TTCAAAAAAAGATAGGCATT

Downstream 100 bases:

>100_bases
TCGAGAACAACATAAGGTGCTTTTCTCTAGCAAATAACATTAATTGCCTATGGATTTAGGCAACATGCCTCTCTGTAGTT
TAGTATAATTCAGCTCCATA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSILEKIQNQRSNLSANGIKILDFILEQPAAIGAYSSQELANRVQVSQSSIIKLTQKLGFKGFTAFKLAIIEDIGRKHAI
LEPEKPIHNKIHSDDSSLTMAQKLVQEKHHALVATTNAIDYQEFEHIISLLNNANRIQIIGIGGSALTAKDLSFKLLKIG
MTALSEQDSHVQIATANTLSNTDVQMAIEKGATVIALTSTKKSPLRKVASYCIDTIADERQFRSSSISSRTAQNVITDLI
FMTLFQLRSDSAKLLIDKISSTIDSIR

Sequences:

>Translated_267_residues
MSILEKIQNQRSNLSANGIKILDFILEQPAAIGAYSSQELANRVQVSQSSIIKLTQKLGFKGFTAFKLAIIEDIGRKHAI
LEPEKPIHNKIHSDDSSLTMAQKLVQEKHHALVATTNAIDYQEFEHIISLLNNANRIQIIGIGGSALTAKDLSFKLLKIG
MTALSEQDSHVQIATANTLSNTDVQMAIEKGATVIALTSTKKSPLRKVASYCIDTIADERQFRSSSISSRTAQNVITDLI
FMTLFQLRSDSAKLLIDKISSTIDSIR
>Mature_266_residues
SILEKIQNQRSNLSANGIKILDFILEQPAAIGAYSSQELANRVQVSQSSIIKLTQKLGFKGFTAFKLAIIEDIGRKHAIL
EPEKPIHNKIHSDDSSLTMAQKLVQEKHHALVATTNAIDYQEFEHIISLLNNANRIQIIGIGGSALTAKDLSFKLLKIGM
TALSEQDSHVQIATANTLSNTDVQMAIEKGATVIALTSTKKSPLRKVASYCIDTIADERQFRSSSISSRTAQNVITDLIF
MTLFQLRSDSAKLLIDKISSTIDSIR

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=268, Percent_Identity=42.1641791044776, Blast_Score=193, Evalue=8e-51,
Organism=Escherichia coli, GI87082130, Length=263, Percent_Identity=36.5019011406844, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87082369, Length=275, Percent_Identity=21.4545454545455, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788159, Length=265, Percent_Identity=25.6603773584906, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 29348; Mature: 29217

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILEKIQNQRSNLSANGIKILDFILEQPAAIGAYSSQELANRVQVSQSSIIKLTQKLGF
CCHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KGFTAFKLAIIEDIGRKHAILEPEKPIHNKIHSDDSSLTMAQKLVQEKHHALVATTNAID
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCC
YQEFEHIISLLNNANRIQIIGIGGSALTAKDLSFKLLKIGMTALSEQDSHVQIATANTLS
HHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
NTDVQMAIEKGATVIALTSTKKSPLRKVASYCIDTIADERQFRSSSISSRTAQNVITDLI
CCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMTLFQLRSDSAKLLIDKISSTIDSIR
HHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILEKIQNQRSNLSANGIKILDFILEQPAAIGAYSSQELANRVQVSQSSIIKLTQKLGF
CHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KGFTAFKLAIIEDIGRKHAILEPEKPIHNKIHSDDSSLTMAQKLVQEKHHALVATTNAID
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCEEEEECCCCC
YQEFEHIISLLNNANRIQIIGIGGSALTAKDLSFKLLKIGMTALSEQDSHVQIATANTLS
HHHHHHHHHHHCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
NTDVQMAIEKGATVIALTSTKKSPLRKVASYCIDTIADERQFRSSSISSRTAQNVITDLI
CCHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMTLFQLRSDSAKLLIDKISSTIDSIR
HHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA