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The map label for this gene is cocE [H]

Identifier: 209694795

GI number: 209694795

Start: 1360921

End: 1362912

Strand: Direct

Name: cocE [H]

Synonym: VSAL_I1253

Alternate gene names: 209694795

Gene position: 1360921-1362912 (Clockwise)

Preceding gene: 209694793

Following gene: 209694796

Centisome position: 40.93

GC content: 42.17

Gene sequence:

>1992_bases
ATGAATACAGTTAAAGAAATTCACCATGATTATCTTACGTTACCCGATGGTACTCGCCTTGCTTATCGAGCTTGGATGCC
AGAAGATGCCCACACTAACCCAGTCCCTGCTATTTTAGAGTTTCTTCCTTATCGAAAAAATGACGGCACAATCATCCGTG
ATGAAATCACCATGCCCCAAACGGCTGCACAAGGTTATGCTTGTGTGCGAGTCGATTTAAGAGGGTGTGGAGAATCTGAA
GGTTTCATGACGGATGAGTATTCCACTCAAGAATTACAAGATGGCTGTGATGTGATCACTTGGATTGCTGCTCAAGCGTG
GTGTAACGGTAATCTTGGTATGGTGGGGATTTCGTGGGGTGGCTTTAATTCTTTACAAGTCGCCGCGTTAAATCCACCTG
CTTTAAAAGCAATCATCACCCAGTGTTCAACGGACGACCGCTATCGTGATGACATTCATTTTAATGGTGGCTGTCTATTA
AATGACAACATGGATTGGGCTGCGTTTTTTTGGGCTTACGCGCAAGGTCGCTCGCCGGACAAGGCGCTTGTTGGGGAAAA
CTGGAAAGAAATTTGGCTAGAGCGATTAGAAAATATGCCTTTTTTAGCCAAGCCTTGGTTAACAGAGCAAATACGTAATG
ACTATTGGAAACACGGTTCGGTGTGTGAAAAATATTCTGATATTAAGATCCCAGTATATGCAATGGGAGGCTGGGCTGAT
GGTTATCGTAATACCGTATTTACTTTGCTTCAGAATCTTGATGTTCCGACAAAAGGGTTAGTGGGACCTTGGGCGCATAA
ATACCCCAATATCGCGTTTCCTAATCCTAAAATGGATTACGTAAAAGAATCGGTACGTTGGTGGGATCGCTGGCTTAAAG
GTATCGATAACGGAATTATGGATGAGCCTAAACTCAATTATTATTTACAAGACAGTGTGACGCCGGCAACGGATTATGAC
ACTCGTCCAGGGAAGTGGGTATCGGAACCTGATTGGCCCTCTGACAATACGCAATATCAAATTTGGCATCTATCGGATAG
TGGATTGAAAACCACGGCAAGTGAATCGGATACGATGAGTATTTGCTCACCACAAACGGTTGGGCTTGATGGTGGCCGCT
TTTGCGCGGGCATTCGATTAGATATGGAGCATCCTGCGGATCAACGTATAGATGACTCTGGATCATTGGTGTTTGATTCT
CTGATATTAGAGCAAGAGGTATCGATTGCAGGCCAAGTGCTCGCTAATCTCAATTTGTCGAGTGATAAACCTCAAGCGAG
TGTGATTGTTCGAATTTCTGATGTACATCCTAATGGGCAAGTAACAAAAGTCAGCCATGGTATTTTAAATTTGACTCATA
GAGACAGTCATGAGTTTCCCCAAGCGTTAAATCCTGATGAAAGGTATGACATTGAAATAAAAGTAAATCACATGGCGTAT
GTTATCCCTAAAGGGCATAAAATTCGTATTGCGATTTCGACCGCTTACTGGCCTCTTATTTGGCCGACAGCAGATAATGC
AACACTGACTGTTTACCCACAACACAGTTCGATTACTTTGCCAGTTAATGCTCAACCAATATGTTCAAAATCAGTACCAG
AGCACAATAAAACCGTTTCGTTTAACGGTAAGATATTAAGACCGTCAGACAGTAAACGGGTGACTCATCGGGACTACAAA
ACCGGGGTCGTAACGCTTGAAACTATGGAGGATTTTGGACGACAATTTTATGAATCATCACAAAGTGAAATCGATTTTAT
TATTCATCAAGAACTGAGCATTCATCCTGATGATCCTTTGAGTGCCAAAAATGATATCCGATTGAAAGTGGATATGGGAC
GTGAAGGGTGGTGGACAGGGATTGAATGCCATTATGAAATGATTTGTGACCATGATTATTTTTATATCACAGCAAACTGG
AAAGCTTTTTATGACAATGATGTCGTTTTTGAAAAGCAGTTTACAGAAACTATCAAGCGTCACTTTATGTAA

Upstream 100 bases:

>100_bases
TATTCTGAACTTTTAGTTAAGGATATGTTAACTAAAAAGCGGTTTACGCACAACGCTAGCCTTCTATGATGTTGATATCA
GTTCTATTATTAAGGTTCGC

Downstream 100 bases:

>100_bases
GCACGTTCAAGGAAGAAATCATGTTAAAATCAATACGCCCTTTGGTGTTTTTCCCTACATTTTTAGTTTTAGTGGCAGCA
CTGATTCTCAGTCTTGTGGA

Product: X-Pro dipeptidyl-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MNTVKEIHHDYLTLPDGTRLAYRAWMPEDAHTNPVPAILEFLPYRKNDGTIIRDEITMPQTAAQGYACVRVDLRGCGESE
GFMTDEYSTQELQDGCDVITWIAAQAWCNGNLGMVGISWGGFNSLQVAALNPPALKAIITQCSTDDRYRDDIHFNGGCLL
NDNMDWAAFFWAYAQGRSPDKALVGENWKEIWLERLENMPFLAKPWLTEQIRNDYWKHGSVCEKYSDIKIPVYAMGGWAD
GYRNTVFTLLQNLDVPTKGLVGPWAHKYPNIAFPNPKMDYVKESVRWWDRWLKGIDNGIMDEPKLNYYLQDSVTPATDYD
TRPGKWVSEPDWPSDNTQYQIWHLSDSGLKTTASESDTMSICSPQTVGLDGGRFCAGIRLDMEHPADQRIDDSGSLVFDS
LILEQEVSIAGQVLANLNLSSDKPQASVIVRISDVHPNGQVTKVSHGILNLTHRDSHEFPQALNPDERYDIEIKVNHMAY
VIPKGHKIRIAISTAYWPLIWPTADNATLTVYPQHSSITLPVNAQPICSKSVPEHNKTVSFNGKILRPSDSKRVTHRDYK
TGVVTLETMEDFGRQFYESSQSEIDFIIHQELSIHPDDPLSAKNDIRLKVDMGREGWWTGIECHYEMICDHDYFYITANW
KAFYDNDVVFEKQFTETIKRHFM

Sequences:

>Translated_663_residues
MNTVKEIHHDYLTLPDGTRLAYRAWMPEDAHTNPVPAILEFLPYRKNDGTIIRDEITMPQTAAQGYACVRVDLRGCGESE
GFMTDEYSTQELQDGCDVITWIAAQAWCNGNLGMVGISWGGFNSLQVAALNPPALKAIITQCSTDDRYRDDIHFNGGCLL
NDNMDWAAFFWAYAQGRSPDKALVGENWKEIWLERLENMPFLAKPWLTEQIRNDYWKHGSVCEKYSDIKIPVYAMGGWAD
GYRNTVFTLLQNLDVPTKGLVGPWAHKYPNIAFPNPKMDYVKESVRWWDRWLKGIDNGIMDEPKLNYYLQDSVTPATDYD
TRPGKWVSEPDWPSDNTQYQIWHLSDSGLKTTASESDTMSICSPQTVGLDGGRFCAGIRLDMEHPADQRIDDSGSLVFDS
LILEQEVSIAGQVLANLNLSSDKPQASVIVRISDVHPNGQVTKVSHGILNLTHRDSHEFPQALNPDERYDIEIKVNHMAY
VIPKGHKIRIAISTAYWPLIWPTADNATLTVYPQHSSITLPVNAQPICSKSVPEHNKTVSFNGKILRPSDSKRVTHRDYK
TGVVTLETMEDFGRQFYESSQSEIDFIIHQELSIHPDDPLSAKNDIRLKVDMGREGWWTGIECHYEMICDHDYFYITANW
KAFYDNDVVFEKQFTETIKRHFM
>Mature_663_residues
MNTVKEIHHDYLTLPDGTRLAYRAWMPEDAHTNPVPAILEFLPYRKNDGTIIRDEITMPQTAAQGYACVRVDLRGCGESE
GFMTDEYSTQELQDGCDVITWIAAQAWCNGNLGMVGISWGGFNSLQVAALNPPALKAIITQCSTDDRYRDDIHFNGGCLL
NDNMDWAAFFWAYAQGRSPDKALVGENWKEIWLERLENMPFLAKPWLTEQIRNDYWKHGSVCEKYSDIKIPVYAMGGWAD
GYRNTVFTLLQNLDVPTKGLVGPWAHKYPNIAFPNPKMDYVKESVRWWDRWLKGIDNGIMDEPKLNYYLQDSVTPATDYD
TRPGKWVSEPDWPSDNTQYQIWHLSDSGLKTTASESDTMSICSPQTVGLDGGRFCAGIRLDMEHPADQRIDDSGSLVFDS
LILEQEVSIAGQVLANLNLSSDKPQASVIVRISDVHPNGQVTKVSHGILNLTHRDSHEFPQALNPDERYDIEIKVNHMAY
VIPKGHKIRIAISTAYWPLIWPTADNATLTVYPQHSSITLPVNAQPICSKSVPEHNKTVSFNGKILRPSDSKRVTHRDYK
TGVVTLETMEDFGRQFYESSQSEIDFIIHQELSIHPDDPLSAKNDIRLKVDMGREGWWTGIECHYEMICDHDYFYITANW
KAFYDNDVVFEKQFTETIKRHFM

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 75596; Mature: 75596

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVKEIHHDYLTLPDGTRLAYRAWMPEDAHTNPVPAILEFLPYRKNDGTIIRDEITMPQ
CCCHHHHHHCEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
TAAQGYACVRVDLRGCGESEGFMTDEYSTQELQDGCDVITWIAAQAWCNGNLGMVGISWG
HHHCCEEEEEEEECCCCCCCCEECCCCCHHHHHCCHHHHHHHHHHHEECCCEEEEEEECC
GFNSLQVAALNPPALKAIITQCSTDDRYRDDIHFNGGCLLNDNMDWAAFFWAYAQGRSPD
CCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEECCCEEEECCCCHHHHEEHHHCCCCCC
KALVGENWKEIWLERLENMPFLAKPWLTEQIRNDYWKHGSVCEKYSDIKIPVYAMGGWAD
CCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCC
GYRNTVFTLLQNLDVPTKGLVGPWAHKYPNIAFPNPKMDYVKESVRWWDRWLKGIDNGIM
CHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DEPKLNYYLQDSVTPATDYDTRPGKWVSEPDWPSDNTQYQIWHLSDSGLKTTASESDTMS
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCEE
ICSPQTVGLDGGRFCAGIRLDMEHPADQRIDDSGSLVFDSLILEQEVSIAGQVLANLNLS
ECCCCEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCC
SDKPQASVIVRISDVHPNGQVTKVSHGILNLTHRDSHEFPQALNPDERYDIEIKVNHMAY
CCCCCEEEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEE
VIPKGHKIRIAISTAYWPLIWPTADNATLTVYPQHSSITLPVNAQPICSKSVPEHNKTVS
EECCCCEEEEEEEECCCEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEE
FNGKILRPSDSKRVTHRDYKTGVVTLETMEDFGRQFYESSQSEIDFIIHQELSIHPDDPL
ECCEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
SAKNDIRLKVDMGREGWWTGIECHYEMICDHDYFYITANWKAFYDNDVVFEKQFTETIKR
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCEEEEEECCEEEECCCEEEHHHHHHHHHH
HFM
HCC
>Mature Secondary Structure
MNTVKEIHHDYLTLPDGTRLAYRAWMPEDAHTNPVPAILEFLPYRKNDGTIIRDEITMPQ
CCCHHHHHHCEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEEECCCCCC
TAAQGYACVRVDLRGCGESEGFMTDEYSTQELQDGCDVITWIAAQAWCNGNLGMVGISWG
HHHCCEEEEEEEECCCCCCCCEECCCCCHHHHHCCHHHHHHHHHHHEECCCEEEEEEECC
GFNSLQVAALNPPALKAIITQCSTDDRYRDDIHFNGGCLLNDNMDWAAFFWAYAQGRSPD
CCCCEEEEEECCHHHHHHHHHCCCCCCCCCCEEECCCEEEECCCCHHHHEEHHHCCCCCC
KALVGENWKEIWLERLENMPFLAKPWLTEQIRNDYWKHGSVCEKYSDIKIPVYAMGGWAD
CCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCHHHHCCCCEEEEEEECCCCC
GYRNTVFTLLQNLDVPTKGLVGPWAHKYPNIAFPNPKMDYVKESVRWWDRWLKGIDNGIM
CHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
DEPKLNYYLQDSVTPATDYDTRPGKWVSEPDWPSDNTQYQIWHLSDSGLKTTASESDTMS
CCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCEE
ICSPQTVGLDGGRFCAGIRLDMEHPADQRIDDSGSLVFDSLILEQEVSIAGQVLANLNLS
ECCCCEECCCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCC
SDKPQASVIVRISDVHPNGQVTKVSHGILNLTHRDSHEFPQALNPDERYDIEIKVNHMAY
CCCCCEEEEEEEEECCCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEE
VIPKGHKIRIAISTAYWPLIWPTADNATLTVYPQHSSITLPVNAQPICSKSVPEHNKTVS
EECCCCEEEEEEEECCCEEEEECCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEE
FNGKILRPSDSKRVTHRDYKTGVVTLETMEDFGRQFYESSQSEIDFIIHQELSIHPDDPL
ECCEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCC
SAKNDIRLKVDMGREGWWTGIECHYEMICDHDYFYITANWKAFYDNDVVFEKQFTETIKR
CCCCCEEEEEECCCCCCCCCEEEEEEEEECCCEEEEEECCEEEECCCEEEHHHHHHHHHH
HFM
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]