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The map label for this gene is 209694759

Identifier: 209694759

GI number: 209694759

Start: 1323029

End: 1323775

Strand: Direct

Name: 209694759

Synonym: VSAL_I1214

Alternate gene names: NA

Gene position: 1323029-1323775 (Clockwise)

Preceding gene: 209694756

Following gene: 209694760

Centisome position: 39.79

GC content: 38.02

Gene sequence:

>747_bases
ATGAAATTTATGTTTAAACTTACTCTCGCATTACTAAGTTCGGTTATCGGCTTTAATGCAGCAGCAGAGCCTGTAGTTAA
ACCGCTTCAATTTGAAGAAATCACGAATAATGTGTTTTTAGTTAAATCGTATCGTGAATTTAAAAACTTACAGAGCCCAA
AGAAACCTATTTTGGTCGATGCTAATTCTTTAGTGTATGTTGATGGAAAGGATGCGTATTTGATTGATACGCCATGGAAT
GCGTCGAACATGCCTCAGTTGATGACGTGGATTGAAAACAGAGGATTAACATTAAAGAAAACGGTCTTTTCTCATTTTCA
TGAAGATCAAACTGGTGGTTTAGAATACCTGCAAGAACATCACTTTGAGACTTACGCGTCTGCATTAACGAACAAATTTT
TGAAAGGTGATAACAAGAAAGCGACGAATCATCAATTTTCAGGTGATAATTTTGTGTTGTTAGAAAATAAGATTGAAGTT
TTCTATCCGGGAGGAGGCCATACTAAAGACAATGCGGTGGTATGGTTACCAAAAGAAAAAGTATTACTTGGCGGTTGTTT
AATGCGAGCAAATGAGGTGAATACGATTGGGTGGACTGGTGATGCCGATATGAAAGCATGGGCGGGGTCTGCTCAAAAAG
TCTTAACGAAATACCCTCAAGCAAATTTTGTTGTTCCTGGACACGGGAACGTTGGTGAAGGGACGAGTATTATTAGTCAT
ACTGTCGATATTACCGGAAAAATTTAG

Upstream 100 bases:

>100_bases
ATAAACGAAGACTCCGTATTGATCTTAATGAATGTTTTACATTTAATTAACAGTAGTAAGAGGGAGAATATTGTATGTTT
ACAGTTATATTTAAAAAGGA

Downstream 100 bases:

>100_bases
CCAATCTTATGAAAAGGAATTTTGAGAAATAGTGCTTTTTTGTTTTTATATCGACTTTTAATATTTTATTATCGCTTTGC
GATAAAATTATATTGATTTG

Product: mobile metallo-beta-lactamase

Products: NA

Alternate protein names: BLAIMP; Beta-lactamase type II; Penicillinase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKFMFKLTLALLSSVIGFNAAAEPVVKPLQFEEITNNVFLVKSYREFKNLQSPKKPILVDANSLVYVDGKDAYLIDTPWN
ASNMPQLMTWIENRGLTLKKTVFSHFHEDQTGGLEYLQEHHFETYASALTNKFLKGDNKKATNHQFSGDNFVLLENKIEV
FYPGGGHTKDNAVVWLPKEKVLLGGCLMRANEVNTIGWTGDADMKAWAGSAQKVLTKYPQANFVVPGHGNVGEGTSIISH
TVDITGKI

Sequences:

>Translated_248_residues
MKFMFKLTLALLSSVIGFNAAAEPVVKPLQFEEITNNVFLVKSYREFKNLQSPKKPILVDANSLVYVDGKDAYLIDTPWN
ASNMPQLMTWIENRGLTLKKTVFSHFHEDQTGGLEYLQEHHFETYASALTNKFLKGDNKKATNHQFSGDNFVLLENKIEV
FYPGGGHTKDNAVVWLPKEKVLLGGCLMRANEVNTIGWTGDADMKAWAGSAQKVLTKYPQANFVVPGHGNVGEGTSIISH
TVDITGKI
>Mature_248_residues
MKFMFKLTLALLSSVIGFNAAAEPVVKPLQFEEITNNVFLVKSYREFKNLQSPKKPILVDANSLVYVDGKDAYLIDTPWN
ASNMPQLMTWIENRGLTLKKTVFSHFHEDQTGGLEYLQEHHFETYASALTNKFLKGDNKKATNHQFSGDNFVLLENKIEV
FYPGGGHTKDNAVVWLPKEKVLLGGCLMRANEVNTIGWTGDADMKAWAGSAQKVLTKYPQANFVVPGHGNVGEGTSIISH
TVDITGKI

Specific function: Confers resistance to imipenem and broad-spectrum beta- lactams. Also hydrolyzes carbapenems [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27608; Mature: 27608

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFMFKLTLALLSSVIGFNAAAEPVVKPLQFEEITNNVFLVKSYREFKNLQSPKKPILVD
CCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCEEEEECHHHHHHCCCCCCCEEEE
ANSLVYVDGKDAYLIDTPWNASNMPQLMTWIENRGLTLKKTVFSHFHEDQTGGLEYLQEH
CCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEHHHHHHHHCCCCCCCHHHHHHH
HFETYASALTNKFLKGDNKKATNHQFSGDNFVLLENKIEVFYPGGGHTKDNAVVWLPKEK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCCEEEEECCCC
VLLGGCLMRANEVNTIGWTGDADMKAWAGSAQKVLTKYPQANFVVPGHGNVGEGTSIISH
EEEHHHHEECCCCCEEECCCCCCHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCCEEEE
TVDITGKI
EEEEEECC
>Mature Secondary Structure
MKFMFKLTLALLSSVIGFNAAAEPVVKPLQFEEITNNVFLVKSYREFKNLQSPKKPILVD
CCHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHCCCEEEEECHHHHHHCCCCCCCEEEE
ANSLVYVDGKDAYLIDTPWNASNMPQLMTWIENRGLTLKKTVFSHFHEDQTGGLEYLQEH
CCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEHHHHHHHHCCCCCCCHHHHHHH
HFETYASALTNKFLKGDNKKATNHQFSGDNFVLLENKIEVFYPGGGHTKDNAVVWLPKEK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCCEEEEECCCC
VLLGGCLMRANEVNTIGWTGDADMKAWAGSAQKVLTKYPQANFVVPGHGNVGEGTSIISH
EEEHHHHEECCCCCEEECCCCCCHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCCEEEE
TVDITGKI
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8141584 [H]