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The map label for this gene is dcuC [H]

Identifier: 209694740

GI number: 209694740

Start: 1300729

End: 1302093

Strand: Direct

Name: dcuC [H]

Synonym: VSAL_I1194

Alternate gene names: 209694740

Gene position: 1300729-1302093 (Clockwise)

Preceding gene: 209694739

Following gene: 209694742

Centisome position: 39.12

GC content: 41.83

Gene sequence:

>1365_bases
ATGGCTCAGTTAATATTGGTTCTTATTATTGTCGTTATTGCCGCCAGAATGATTCTAAAAGGCTACAAAGCAGAGCCTAC
CTTACTTATGTCAGGGACTGTTTTAATTTTTGCTACTGGGATATTTGGTTGGGGACCGATGCTTCCAACTTCTGTGGCAT
CAACCAATTTTTCAGGGTTTGATCCGTTTAAGTATATCCAATTTTTGATGGGATATCGTGCGGGTGCATTAGGTTTGATG
ATAATGGCGTTAGTCGGTTTTGCTGATTATATGAGTCATATCGGTGCTAACGATGTAGTCGTTCGCTTAGCTACAAAACC
ATTAAGTCGCATTAAAAACAAAAATATCATGCTGTTCTTTGCTTATTGTATGGCGAGTATTCTTCAACTCGCGATCCCAT
CCGCAACCGGATTAGGTGTGTTATTAATGGGGACTTTGTATCCCGTAATGTTAGGTTTAGGTCTTTCTCGTGGTAGTGCT
GCTGCGGTTATTGCTAGTTCATTGGCGGTAAGTTTTACGCCAACGGGTGTTGATGCTATTCGTGCTAGTGAAGCATTAGG
AATGGATTTAATGAGCTACGTTTCTCATTACCAAGCGCCAACATCTATTGCAACAATGGTCGTGATCGGGATTATGCATG
TTATCTGGCAAACCCATGTAGATAAAAAACACCCAGAGCAGTTTGAAGAAGCCACATTAGCTGAATCAAAAGAGGGGAGC
TCTGCGCCGAGTTACTATGTAATGCTCCCTTTACTTCCTATTATTATGGCTGTGTTTTTTTCAAAATTAGTGGTTTCAAC
CATTAATATGGATGTGACGACAATAGTATTTGTCTCTATGTTTATCGCCATGCTGTGTGAATGTGTTACGAAAAGAAGCC
TAAAGGTTGTGTTTGATGGCTTTGGTGTCTTTTCAAAAGGAATGGGGAGTGCGTTTAGTAGCGTCGTTGTTTTACTCGTG
GCAGCTGGTGTTTTTGCGTATGGTATTCAAGCGACGGGTGCTATTGCTAACTTAATCATGCTTGCCGAATCGGTTGGTTT
ACCAAGTGTTGCTATGACGTTAGTTTTTGCTGTTGTTACCCTATTGGCAGCAGTGATTATGGGGTCAGGAAATGCGCCAT
TCTTAGCGTTTGTTGAATTAATTCCAACTATCGCAGCAAGCATGGGAGCAAATACCGCAGCGATGTTAATGCCAATGCAA
CAAGCTTCGGCAATTGGTCGTGGAATGTCTCCGGTGTCGGCGGTTGTTATTGCGTCAGCAACAGGAGCGAAGTTAAGTCC
TTTTGATGTAGCCAAGCGCACTTCAGTACCTGTGCTAGTTGGATTTGTATTCCACTTTATTATCGTATATGCATTTTATA
GCTAA

Upstream 100 bases:

>100_bases
ATTCAATATTTGAGTATTTGCCTGTTCCATCACTAATGGCTGCAAGTAACGTGGTTAAGACAATTATTATCAACTTAACA
GAGCATGAAGGTATATAAAT

Downstream 100 bases:

>100_bases
ATTGCGTTTATATATATTTGATATAAAAAAGCCGCACTCCCTAAAATTCTCACAAAATAGGGGAGTGCGGCTTTCTAATT
CTTTGTTTGGAAATGTACGT

Product: anaerobic C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAQLILVLIIVVIAARMILKGYKAEPTLLMSGTVLIFATGIFGWGPMLPTSVASTNFSGFDPFKYIQFLMGYRAGALGLM
IMALVGFADYMSHIGANDVVVRLATKPLSRIKNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGLSRGSA
AAVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSIATMVVIGIMHVIWQTHVDKKHPEQFEEATLAESKEGS
SAPSYYVMLPLLPIIMAVFFSKLVVSTINMDVTTIVFVSMFIAMLCECVTKRSLKVVFDGFGVFSKGMGSAFSSVVVLLV
AAGVFAYGIQATGAIANLIMLAESVGLPSVAMTLVFAVVTLLAAVIMGSGNAPFLAFVELIPTIAASMGANTAAMLMPMQ
QASAIGRGMSPVSAVVIASATGAKLSPFDVAKRTSVPVLVGFVFHFIIVYAFYS

Sequences:

>Translated_454_residues
MAQLILVLIIVVIAARMILKGYKAEPTLLMSGTVLIFATGIFGWGPMLPTSVASTNFSGFDPFKYIQFLMGYRAGALGLM
IMALVGFADYMSHIGANDVVVRLATKPLSRIKNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGLSRGSA
AAVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSIATMVVIGIMHVIWQTHVDKKHPEQFEEATLAESKEGS
SAPSYYVMLPLLPIIMAVFFSKLVVSTINMDVTTIVFVSMFIAMLCECVTKRSLKVVFDGFGVFSKGMGSAFSSVVVLLV
AAGVFAYGIQATGAIANLIMLAESVGLPSVAMTLVFAVVTLLAAVIMGSGNAPFLAFVELIPTIAASMGANTAAMLMPMQ
QASAIGRGMSPVSAVVIASATGAKLSPFDVAKRTSVPVLVGFVFHFIIVYAFYS
>Mature_453_residues
AQLILVLIIVVIAARMILKGYKAEPTLLMSGTVLIFATGIFGWGPMLPTSVASTNFSGFDPFKYIQFLMGYRAGALGLMI
MALVGFADYMSHIGANDVVVRLATKPLSRIKNKNIMLFFAYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGLSRGSAA
AVIASSLAVSFTPTGVDAIRASEALGMDLMSYVSHYQAPTSIATMVVIGIMHVIWQTHVDKKHPEQFEEATLAESKEGSS
APSYYVMLPLLPIIMAVFFSKLVVSTINMDVTTIVFVSMFIAMLCECVTKRSLKVVFDGFGVFSKGMGSAFSSVVVLLVA
AGVFAYGIQATGAIANLIMLAESVGLPSVAMTLVFAVVTLLAAVIMGSGNAPFLAFVELIPTIAASMGANTAAMLMPMQQ
ASAIGRGMSPVSAVVIASATGAKLSPFDVAKRTSVPVLVGFVFHFIIVYAFYS

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=423, Percent_Identity=46.0992907801418, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1789622, Length=452, Percent_Identity=35.1769911504425, Blast_Score=261, Evalue=7e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47887; Mature: 47756

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLILVLIIVVIAARMILKGYKAEPTLLMSGTVLIFATGIFGWGPMLPTSVASTNFSGF
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCCCCHHHCCCCCCC
DPFKYIQFLMGYRAGALGLMIMALVGFADYMSHIGANDVVVRLATKPLSRIKNKNIMLFF
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCCCEEEEH
AYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGLSRGSAAAVIASSLAVSFTPTGVDAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCHHHH
RASEALGMDLMSYVSHYQAPTSIATMVVIGIMHVIWQTHVDKKHPEQFEEATLAESKEGS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
SAPSYYVMLPLLPIIMAVFFSKLVVSTINMDVTTIVFVSMFIAMLCECVTKRSLKVVFDG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
FGVFSKGMGSAFSSVVVLLVAAGVFAYGIQATGAIANLIMLAESVGLPSVAMTLVFAVVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLAAVIMGSGNAPFLAFVELIPTIAASMGANTAAMLMPMQQASAIGRGMSPVSAVVIASA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEC
TGAKLSPFDVAKRTSVPVLVGFVFHFIIVYAFYS
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQLILVLIIVVIAARMILKGYKAEPTLLMSGTVLIFATGIFGWGPMLPTSVASTNFSGF
HHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCCCCHHHCCCCCCC
DPFKYIQFLMGYRAGALGLMIMALVGFADYMSHIGANDVVVRLATKPLSRIKNKNIMLFF
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEHHHHHHHHHCCCCEEEEH
AYCMASILQLAIPSATGLGVLLMGTLYPVMLGLGLSRGSAAAVIASSLAVSFTPTGVDAI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCHHHH
RASEALGMDLMSYVSHYQAPTSIATMVVIGIMHVIWQTHVDKKHPEQFEEATLAESKEGS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
SAPSYYVMLPLLPIIMAVFFSKLVVSTINMDVTTIVFVSMFIAMLCECVTKRSLKVVFDG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHC
FGVFSKGMGSAFSSVVVLLVAAGVFAYGIQATGAIANLIMLAESVGLPSVAMTLVFAVVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LLAAVIMGSGNAPFLAFVELIPTIAASMGANTAAMLMPMQQASAIGRGMSPVSAVVIASA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHEEEC
TGAKLSPFDVAKRTSVPVLVGFVFHFIIVYAFYS
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]