Click here to switch to the map view.

The map label for this gene is menC

Identifier: 209694660

GI number: 209694660

Start: 1198806

End: 1199780

Strand: Direct

Name: menC

Synonym: VSAL_I1102

Alternate gene names: 209694660

Gene position: 1198806-1199780 (Clockwise)

Preceding gene: 209694659

Following gene: 209694661

Centisome position: 36.05

GC content: 41.64

Gene sequence:

>975_bases
ATGAAAACAGCCAAGATATATCAATATCAACTCCCTATGGACAGTGGAGTGATTCTTCGTGATCAACGTCTTCAACAAAG
AGATGGGTTGATCATTGAATTAAGTGATGGAAAACACACTGCAAAAGGTGAGATTGCGCCTTTACCTGAATTTAGCCAAG
AAAATTTAGAACAAGCACGTGAAGATTTAATCTCATTAACTCAAGCGTGGCTAAATGATGAAGTTCTGGATGTGGATGCC
AATTGTCCCTCTGTTGCTTTTGGTTTTAGCATGGCGTTACTTGAGCTTGAAAATAATCTACCTGAAGTTGGTAATTATCA
AGTTGCTCCTTTATGTTCTGGTGATCCAGACGATTTAGTGGTGAAGCTAAATGAGATGAGTGGTAAGAAAGTCGCGAAAA
TTAAAGTTGGAATGTATGAAGCGATTCGTGATGGAATGGTTGCGAATATGTTTTTAGAGTTGATCCCCGACCTCTCTTTA
CGTCTTGATGCTAATCGCGGTTGGACTCCTAAAAAAGCAGAGCAATTTGCGAATTATGTTAGCCCGCAATACCGTTCTCG
CATTGAGTTTTTAGAAGAGCCTTGCCATAGACCAGAAGAAAGTCTTGAATTTTCTAAAGCGACGGGAATTGCCATTGCGT
GGGATGAAACCGTACGTGATGAAGGTTTTGAAGTGAAAGCTCAAGATGGCGTGGCGGCAATCGTAATTAAACCGACGTTA
GTTGGCTCTGTCGGTAAATGTATTGAACTTGTTGAGCAGGCACACCTGTTAGGAATGCAAGCTGTGATCAGTTCAAGTAT
TGAATCAAGCTTAGCGCTAACACAACTTGCACGACTTGCTGCTTGGAAAACACCGAATACGATCCCTGGTTTAGATACCA
TCGATTTATTTAAAATGCAGTTAGACACACCGTGGCCTCATTGTGAGTTACCGATGCAAGCGCTGTCCGATCTCGAGGTG
ATATGGGAAAGTTAA

Upstream 100 bases:

>100_bases
TAAATTCCCTCGTAATCCATAAGCGACACTATCACTTATTTTGATAAGTTTGAGAGGCTCTCTGGAGTCTCTTTTTTCTT
TTTATTGGTTGGAGTAACAA

Downstream 100 bases:

>100_bases
TTACGCCTGAATTTACAACTTGGCCGTGGGTTAAGTGGAGTGAAACACGTGAGCTTGAAATCGCATTACGAGATGGTGAT
ACGATCTGGACATGGGCTGA

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKTAKIYQYQLPMDSGVILRDQRLQQRDGLIIELSDGKHTAKGEIAPLPEFSQENLEQAREDLISLTQAWLNDEVLDVDA
NCPSVAFGFSMALLELENNLPEVGNYQVAPLCSGDPDDLVVKLNEMSGKKVAKIKVGMYEAIRDGMVANMFLELIPDLSL
RLDANRGWTPKKAEQFANYVSPQYRSRIEFLEEPCHRPEESLEFSKATGIAIAWDETVRDEGFEVKAQDGVAAIVIKPTL
VGSVGKCIELVEQAHLLGMQAVISSSIESSLALTQLARLAAWKTPNTIPGLDTIDLFKMQLDTPWPHCELPMQALSDLEV
IWES

Sequences:

>Translated_324_residues
MKTAKIYQYQLPMDSGVILRDQRLQQRDGLIIELSDGKHTAKGEIAPLPEFSQENLEQAREDLISLTQAWLNDEVLDVDA
NCPSVAFGFSMALLELENNLPEVGNYQVAPLCSGDPDDLVVKLNEMSGKKVAKIKVGMYEAIRDGMVANMFLELIPDLSL
RLDANRGWTPKKAEQFANYVSPQYRSRIEFLEEPCHRPEESLEFSKATGIAIAWDETVRDEGFEVKAQDGVAAIVIKPTL
VGSVGKCIELVEQAHLLGMQAVISSSIESSLALTQLARLAAWKTPNTIPGLDTIDLFKMQLDTPWPHCELPMQALSDLEV
IWES
>Mature_324_residues
MKTAKIYQYQLPMDSGVILRDQRLQQRDGLIIELSDGKHTAKGEIAPLPEFSQENLEQAREDLISLTQAWLNDEVLDVDA
NCPSVAFGFSMALLELENNLPEVGNYQVAPLCSGDPDDLVVKLNEMSGKKVAKIKVGMYEAIRDGMVANMFLELIPDLSL
RLDANRGWTPKKAEQFANYVSPQYRSRIEFLEEPCHRPEESLEFSKATGIAIAWDETVRDEGFEVKAQDGVAAIVIKPTL
VGSVGKCIELVEQAHLLGMQAVISSSIESSLALTQLARLAAWKTPNTIPGLDTIDLFKMQLDTPWPHCELPMQALSDLEV
IWES

Specific function: Converts SHCHC to OSB

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1788596, Length=324, Percent_Identity=56.7901234567901, Blast_Score=376, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MENC_ALISL (B6EJ59)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262588.1
- ProteinModelPortal:   B6EJ59
- GeneID:   6988782
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1102
- HOGENOM:   HBG644552
- OMA:   YEANRDG
- ProtClustDB:   PRK05105
- HAMAP:   MF_00470
- InterPro:   IPR013342
- InterPro:   IPR010196
- SMART:   SM00922
- TIGRFAMs:   TIGR01927

Pfam domain/function: PF01188 MR_MLE

EC number: =4.2.1.113

Molecular weight: Translated: 36029; Mature: 36029

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: ACT_SITE 135-135 ACT_SITE 237-237

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAKIYQYQLPMDSGVILRDQRLQQRDGLIIELSDGKHTAKGEIAPLPEFSQENLEQAR
CCCCEEEEEECCCCCCEEEEHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
EDLISLTQAWLNDEVLDVDANCPSVAFGFSMALLELENNLPEVGNYQVAPLCSGDPDDLV
HHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEE
VKLNEMSGKKVAKIKVGMYEAIRDGMVANMFLELIPDLSLRLDANRGWTPKKAEQFANYV
EEEECCCCCEEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHC
SPQYRSRIEFLEEPCHRPEESLEFSKATGIAIAWDETVRDEGFEVKAQDGVAAIVIKPTL
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCHHCCCCCEEEECCCEEEEEECCHH
VGSVGKCIELVEQAHLLGMQAVISSSIESSLALTQLARLAAWKTPNTIPGLDTIDLFKMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEE
LDTPWPHCELPMQALSDLEVIWES
CCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKTAKIYQYQLPMDSGVILRDQRLQQRDGLIIELSDGKHTAKGEIAPLPEFSQENLEQAR
CCCCEEEEEECCCCCCEEEEHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHH
EDLISLTQAWLNDEVLDVDANCPSVAFGFSMALLELENNLPEVGNYQVAPLCSGDPDDLV
HHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEE
VKLNEMSGKKVAKIKVGMYEAIRDGMVANMFLELIPDLSLRLDANRGWTPKKAEQFANYV
EEEECCCCCEEEEEEHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHC
SPQYRSRIEFLEEPCHRPEESLEFSKATGIAIAWDETVRDEGFEVKAQDGVAAIVIKPTL
CHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCHHCCCCCEEEECCCEEEEEECCHH
VGSVGKCIELVEQAHLLGMQAVISSSIESSLALTQLARLAAWKTPNTIPGLDTIDLFKMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEE
LDTPWPHCELPMQALSDLEVIWES
CCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA