Click here to switch to the map view.

The map label for this gene is minD [H]

Identifier: 209694625

GI number: 209694625

Start: 1157829

End: 1158641

Strand: Reverse

Name: minD [H]

Synonym: VSAL_I1066

Alternate gene names: 209694625

Gene position: 1158641-1157829 (Counterclockwise)

Preceding gene: 209694626

Following gene: 209694624

Centisome position: 34.84

GC content: 40.1

Gene sequence:

>813_bases
ATGGCACGTATTGTCGTTGTGACTTCTGGTAAGGGTGGCGTAGGTAAAACTACTTCCAGCTCTGCCATTGCATCGGGGCT
TGCTCTGGCTGGCAAGAAAACCGCGGTAATTGATTTTGATATTGGCTTACGTAATCTTGATTTAATCATGGGTTGTGAAC
GTCGCGTTGTTTACGATTTTGTTAATGTTATTAATGGTGAAGCAACGCTAAACCAAGCATTAATTAAAGATAAGCGCGTA
GGTAATTTATTTATCCTTCCTGCGTCTCAAACTCGTGATAAAGATGCATTAACCAAAGAAGGCGTTCGTCGTGTTCTTGA
TGAGTTAATCGCAATGAACTTTGATTTCATTATTTGTGATTCTCCAGCAGGTATTGAAGCTGGCGCATTAATGGCGTTAT
ATTTTGCGGATGAAGCCATCATTACCACAAACCCTGAAGTATCATCTGTTCGAGATTCTGACCGCATTTTAGGTATTTTA
GACTCTAAATCTCACCGTTCAGAAGAAGCTTTAGAGCCAGTAAAACAACACCTATTATTAACTCGCTATTGCCCAACACG
TGTAAATCAAGGCGAAATGTTAAGTGTGGGTGATGTTGAAGAAATTCTAAATATCCCTCTATTGGGTGTGATTCCAGAAA
GCCAATCAGTATTGAATGCATCAAACAAAGGTGTACCAGTAATTTTTGACGAAGAATCAAACGCAGGCTCTGCATACCAA
GATGCAGTTGACCGTCTGTTAGGCAAGGAAGTTTCGTTCCGCTTCTTAGAAGAAGAGAAGAAAGGTATCTTTAAACGACT
ATTTGGAGGTTAA

Upstream 100 bases:

>100_bases
ACAAAGAGTATTGGCATCAAAATGTCATGGTCACTATGGTTGAAGACCATATTAAGATCGATACCCTAACGTTATAGCAC
AACATAAAAGGAATAATAAA

Downstream 100 bases:

>100_bases
GCATGGCACTGCTAGAGTTTTTTAGACCACAAAAAAAAGCCACTGCTAACATAGCGAAGGAAAGGCTACAGATCATTGTT
GCTGAACGCAGGAATGGAGG

Product: septum site-determining protein MinD (cell division inhibitor MinD)

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MARIVVVTSGKGGVGKTTSSSAIASGLALAGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQALIKDKRV
GNLFILPASQTRDKDALTKEGVRRVLDELIAMNFDFIICDSPAGIEAGALMALYFADEAIITTNPEVSSVRDSDRILGIL
DSKSHRSEEALEPVKQHLLLTRYCPTRVNQGEMLSVGDVEEILNIPLLGVIPESQSVLNASNKGVPVIFDEESNAGSAYQ
DAVDRLLGKEVSFRFLEEEKKGIFKRLFGG

Sequences:

>Translated_270_residues
MARIVVVTSGKGGVGKTTSSSAIASGLALAGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQALIKDKRV
GNLFILPASQTRDKDALTKEGVRRVLDELIAMNFDFIICDSPAGIEAGALMALYFADEAIITTNPEVSSVRDSDRILGIL
DSKSHRSEEALEPVKQHLLLTRYCPTRVNQGEMLSVGDVEEILNIPLLGVIPESQSVLNASNKGVPVIFDEESNAGSAYQ
DAVDRLLGKEVSFRFLEEEKKGIFKRLFGG
>Mature_269_residues
ARIVVVTSGKGGVGKTTSSSAIASGLALAGKKTAVIDFDIGLRNLDLIMGCERRVVYDFVNVINGEATLNQALIKDKRVG
NLFILPASQTRDKDALTKEGVRRVLDELIAMNFDFIICDSPAGIEAGALMALYFADEAIITTNPEVSSVRDSDRILGILD
SKSHRSEEALEPVKQHLLLTRYCPTRVNQGEMLSVGDVEEILNIPLLGVIPESQSVLNASNKGVPVIFDEESNAGSAYQD
AVDRLLGKEVSFRFLEEEKKGIFKRLFGG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=78.5185185185185, Blast_Score=427, Evalue=1e-121,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29287; Mature: 29156

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIVVVTSGKGGVGKTTSSSAIASGLALAGKKTAVIDFDIGLRNLDLIMGCERRVVYDF
CEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVINGEATLNQALIKDKRVGNLFILPASQTRDKDALTKEGVRRVLDELIAMNFDFIICD
HHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEC
SPAGIEAGALMALYFADEAIITTNPEVSSVRDSDRILGILDSKSHRSEEALEPVKQHLLL
CCCCCCHHHEEEEEECCCEEEECCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TRYCPTRVNQGEMLSVGDVEEILNIPLLGVIPESQSVLNASNKGVPVIFDEESNAGSAYQ
HHCCCCCCCCCCEEECCCHHHHHCCCEEEEECCCHHHHCCCCCCCEEEEECCCCCCCHHH
DAVDRLLGKEVSFRFLEEEKKGIFKRLFGG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARIVVVTSGKGGVGKTTSSSAIASGLALAGKKTAVIDFDIGLRNLDLIMGCERRVVYDF
EEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVINGEATLNQALIKDKRVGNLFILPASQTRDKDALTKEGVRRVLDELIAMNFDFIICD
HHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEC
SPAGIEAGALMALYFADEAIITTNPEVSSVRDSDRILGILDSKSHRSEEALEPVKQHLLL
CCCCCCHHHEEEEEECCCEEEECCCCHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHH
TRYCPTRVNQGEMLSVGDVEEILNIPLLGVIPESQSVLNASNKGVPVIFDEESNAGSAYQ
HHCCCCCCCCCCEEECCCHHHHHCCCEEEEECCCHHHHCCCCCCCEEEEECCCCCCCHHH
DAVDRLLGKEVSFRFLEEEKKGIFKRLFGG
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]