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The map label for this gene is minC

Identifier: 209694626

GI number: 209694626

Start: 1158665

End: 1159330

Strand: Reverse

Name: minC

Synonym: VSAL_I1067

Alternate gene names: 209694626

Gene position: 1159330-1158665 (Counterclockwise)

Preceding gene: 209694629

Following gene: 209694625

Centisome position: 34.87

GC content: 40.84

Gene sequence:

>666_bases
ATGACAAAAACAGCCGATTTAAAGGGCAGTAATTTCACCCTTTCAGTATTACATTTACCTAATGATGACATCACTCAAGC
CCTTAGTATGCTTGAGCAAAAAGTAGCACAAGCGCCTTCTTTTTTTGCTTCCGCTCCAGTGGTCATTAATATTGAAAATG
TATCGAATGAAATTAATTTTGTTGACCTTAAATTAGGTGTAGAGCGCACAGGTATGATCCCTGTTGGCATTACTGGTTGC
AAAGATAAAGAAAAGCAAGCGCAGGCAACGTCTGCAGGTTTTGCGGTAATGACTTCTTTTACACCTCAGCAAGTAACACA
AAAAGCAAATATGCAACCAACGAAAGTGGTAAGAACCCCTATTCGTTCTGGACAACAAGTGTATGCCAAGGATGCTGACC
TTGTGATCTTAAATCATGTAAGCCCTGGGGCCGAAGTTATCGCCGATGGCAGCATACATATTCACGGCACGTTAAGAGGC
AGAGCAATTGCCGGTGCCAGTGGCCAAAAAGAAGCAAAGATATTTTGCAAAAATTTACAAGCGGAGCTGATATCCATTGC
CGGAAATTATTGGCTAAGCGATCAAATTAACAAAGAGTATTGGCATCAAAATGTCATGGTCACTATGGTTGAAGACCATA
TTAAGATCGATACCCTAACGTTATAG

Upstream 100 bases:

>100_bases
TGCTGTGTGGTCAAACTGACTATAACATGGTATCAGATTTGTGGTATTAAAATTACCGTCTGAAAATCTGAATATTCATA
ACAGCGAAGATACCGAGAGC

Downstream 100 bases:

>100_bases
CACAACATAAAAGGAATAATAAAATGGCACGTATTGTCGTTGTGACTTCTGGTAAGGGTGGCGTAGGTAAAACTACTTCC
AGCTCTGCCATTGCATCGGG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINFVDLKLGVERTGMIPVGITGC
KDKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTPIRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRG
RAIAGASGQKEAKIFCKNLQAELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL

Sequences:

>Translated_221_residues
MTKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINFVDLKLGVERTGMIPVGITGC
KDKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTPIRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRG
RAIAGASGQKEAKIFCKNLQAELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL
>Mature_220_residues
TKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINFVDLKLGVERTGMIPVGITGCK
DKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTPIRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRGR
AIAGASGQKEAKIFCKNLQAELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=226, Percent_Identity=43.8053097345133, Blast_Score=203, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_ALISL (B6EIV8)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262554.1
- GeneID:   6988806
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I1067
- HOGENOM:   HBG399077
- OMA:   KGDTKAR
- ProtClustDB:   PRK04804
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 24046; Mature: 23915

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINF
CCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEECCCCCEEE
VDLKLGVERTGMIPVGITGCKDKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTP
EEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCEEEEECCCHHHHHHHCCCCHHHHHHHH
IRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRGRAIAGASGQKEAKIFCKNLQ
HHCCCEEEECCCCEEEEECCCCCCCEEECCEEEEEEEECCEEEECCCCCHHHHHHHHHHH
AELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL
HHHHHHHCCEEECCCCCHHHHHCCEEEEEEECCEEEEEEEC
>Mature Secondary Structure 
TKTADLKGSNFTLSVLHLPNDDITQALSMLEQKVAQAPSFFASAPVVINIENVSNEINF
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHCCCCEEEEEECCCCCEEE
VDLKLGVERTGMIPVGITGCKDKEKQAQATSAGFAVMTSFTPQQVTQKANMQPTKVVRTP
EEEEECCCCCCEEEEEEECCCCCHHHHHHHCCCEEEEECCCHHHHHHHCCCCHHHHHHHH
IRSGQQVYAKDADLVILNHVSPGAEVIADGSIHIHGTLRGRAIAGASGQKEAKIFCKNLQ
HHCCCEEEECCCCEEEEECCCCCCCEEECCEEEEEEEECCEEEECCCCCHHHHHHHHHHH
AELISIAGNYWLSDQINKEYWHQNVMVTMVEDHIKIDTLTL
HHHHHHHCCEEECCCCCHHHHHCCEEEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA