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The map label for this gene is yicO [C]

Identifier: 209694537

GI number: 209694537

Start: 1076578

End: 1077870

Strand: Direct

Name: yicO [C]

Synonym: VSAL_I0974

Alternate gene names: 209694537

Gene position: 1076578-1077870 (Clockwise)

Preceding gene: 209694528

Following gene: 209694538

Centisome position: 32.38

GC content: 40.99

Gene sequence:

>1293_bases
ATGCTTGAAAAACTATTTCAACTTAAAGCTAATGGTACGAACGTTCGTACTGAAATTATTGCCGGGTTAACCACCTTCTT
AACAATGGCTTATGTTATTTTTGTGAATCCAGCAATCTTGGCTGATGCTGGAATGGATAAAGGCGCTGTTTTTGTTGCAA
CGTGTATTGCTGCTGCAATAGGGTGTTTTATCATGGGATTTGTTGCCAACTTCCCAATAGCTCAAGCTCCAGGTATGGGG
TTGAATGCGTTCTTTACCTACACTGTTGTACTGGGAATGGGTCATACATGGCAAGTAGCGCTCGCTGCTGTATTCATGTC
AGGTGTGTTATTTATTCTTCTAAGTTTATGTAAAATAAGAGAGTTGATTATTAATTCGATTCCTCTTTCTTTACGCACTG
GTATTTCGGCGGGTATTGGTTTATTTTTGGCTTTCATCGCTCTAAAGAATTCAGGCATAGTTGTCGATAATCCGGCAACT
TTATTGTCTATTGGTCATATTAATAGCTTTCCTGCCGCTATGGGGGCATTGGCTTTATTTTTAACTATCGCTTTAGTTCA
TCGTGGCTATAAAGCGGCTGTTATGATCGCTATTTTAGCCGTTACTGGACTTGCCTTGCTTTTTGGTGAAGTTCAATATG
CTGGCATTATGTCAATGCCACCAAGTCTTGCACCTACATTTTTACAACTCGATTTTTCAGGTGCTTTTGACATTGGTATG
CTAAGCGTTGTTTTTGCTTTCTTATTCGTTGATTTATTTGATACTGCCGGTACGTTAGTTGGTGTATCTCAAAAGGCAGG
GATCATGGATAAAGATGGCAATATTCCTCGTCTAAATAGAGCTTTGCTGGCGGATTCAACGGCGACATCTGTAGGGGCTT
TATTAGGTACATCAAACACAACATCATACATTGAAAGTGTTGCTGGTGTAGCTGCCGGTGGTCGAACTGGTTTGACGGCT
GTTGTTGTGGGCATTCTGTTTTTATTGGCTTTATTCTTTGCTCCATTAGCTGGGATGGTTCCTGCTTATGCAACGGCCGG
TGCGTTGTTTTATGTCGCAATCTTAATGATGTCGGGTCTTGTGAGTATTGATTGGAGAGATCTTACTGAAGCGGCGCCAG
TTGTTGTGGTATGCTTGCTAATGCCTTTAACCTTCTCTATTGCTGATGGTATTTCACTAGGCTTTATCTCTTATGCAGCG
ATTAAGTTGTTAAGTGGTAAAGGTCGCGATGTTCATATCAGTGTTTGGGTTCTTGCTGCACTATTCACGCTGAAATTTAT
TTTTACGGCATAG

Upstream 100 bases:

>100_bases
AAATAATCGCTAGAAATTCCCATAATACCTCTTTATAATTCTCAGCCAATCGATTACGCAAACGTTTAATCAGTATAAAG
CAGACTAGGAATGAGCCCCA

Downstream 100 bases:

>100_bases
TTGTTGTTAACTGTGCCACTGAGAGGTTTTGTCTATTATGGCTAATAAATTTGTAATAACTTGGGATAACATGCAGATGT
ATACTCGTCAGCTTGCTGAA

Product: membrane permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MLEKLFQLKANGTNVRTEIIAGLTTFLTMAYVIFVNPAILADAGMDKGAVFVATCIAAAIGCFIMGFVANFPIAQAPGMG
LNAFFTYTVVLGMGHTWQVALAAVFMSGVLFILLSLCKIRELIINSIPLSLRTGISAGIGLFLAFIALKNSGIVVDNPAT
LLSIGHINSFPAAMGALALFLTIALVHRGYKAAVMIAILAVTGLALLFGEVQYAGIMSMPPSLAPTFLQLDFSGAFDIGM
LSVVFAFLFVDLFDTAGTLVGVSQKAGIMDKDGNIPRLNRALLADSTATSVGALLGTSNTTSYIESVAGVAAGGRTGLTA
VVVGILFLLALFFAPLAGMVPAYATAGALFYVAILMMSGLVSIDWRDLTEAAPVVVVCLLMPLTFSIADGISLGFISYAA
IKLLSGKGRDVHISVWVLAALFTLKFIFTA

Sequences:

>Translated_430_residues
MLEKLFQLKANGTNVRTEIIAGLTTFLTMAYVIFVNPAILADAGMDKGAVFVATCIAAAIGCFIMGFVANFPIAQAPGMG
LNAFFTYTVVLGMGHTWQVALAAVFMSGVLFILLSLCKIRELIINSIPLSLRTGISAGIGLFLAFIALKNSGIVVDNPAT
LLSIGHINSFPAAMGALALFLTIALVHRGYKAAVMIAILAVTGLALLFGEVQYAGIMSMPPSLAPTFLQLDFSGAFDIGM
LSVVFAFLFVDLFDTAGTLVGVSQKAGIMDKDGNIPRLNRALLADSTATSVGALLGTSNTTSYIESVAGVAAGGRTGLTA
VVVGILFLLALFFAPLAGMVPAYATAGALFYVAILMMSGLVSIDWRDLTEAAPVVVVCLLMPLTFSIADGISLGFISYAA
IKLLSGKGRDVHISVWVLAALFTLKFIFTA
>Mature_430_residues
MLEKLFQLKANGTNVRTEIIAGLTTFLTMAYVIFVNPAILADAGMDKGAVFVATCIAAAIGCFIMGFVANFPIAQAPGMG
LNAFFTYTVVLGMGHTWQVALAAVFMSGVLFILLSLCKIRELIINSIPLSLRTGISAGIGLFLAFIALKNSGIVVDNPAT
LLSIGHINSFPAAMGALALFLTIALVHRGYKAAVMIAILAVTGLALLFGEVQYAGIMSMPPSLAPTFLQLDFSGAFDIGM
LSVVFAFLFVDLFDTAGTLVGVSQKAGIMDKDGNIPRLNRALLADSTATSVGALLGTSNTTSYIESVAGVAAGGRTGLTA
VVVGILFLLALFFAPLAGMVPAYATAGALFYVAILMMSGLVSIDWRDLTEAAPVVVVCLLMPLTFSIADGISLGFISYAA
IKLLSGKGRDVHISVWVLAALFTLKFIFTA

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=426, Percent_Identity=49.5305164319249, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1790150, Length=428, Percent_Identity=50.4672897196262, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1790499, Length=426, Percent_Identity=39.2018779342723, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI48994909, Length=426, Percent_Identity=37.793427230047, Blast_Score=254, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44867; Mature: 44867

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKLFQLKANGTNVRTEIIAGLTTFLTMAYVIFVNPAILADAGMDKGAVFVATCIAAAI
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHH
GCFIMGFVANFPIAQAPGMGLNAFFTYTVVLGMGHTWQVALAAVFMSGVLFILLSLCKIR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELIINSIPLSLRTGISAGIGLFLAFIALKNSGIVVDNPATLLSIGHINSFPAAMGALALF
HHHHHCCCHHHHHCHHHHHHHHHHHHHHCCCCEEEECCHHEEEECCCCCHHHHHHHHHHH
LTIALVHRGYKAAVMIAILAVTGLALLFGEVQYAGIMSMPPSLAPTFLQLDFSGAFDIGM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEECCCCCHHHH
LSVVFAFLFVDLFDTAGTLVGVSQKAGIMDKDGNIPRLNRALLADSTATSVGALLGTSNT
HHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCH
TSYIESVAGVAAGGRTGLTAVVVGILFLLALFFAPLAGMVPAYATAGALFYVAILMMSGL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSIDWRDLTEAAPVVVVCLLMPLTFSIADGISLGFISYAAIKLLSGKGRDVHISVWVLAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHH
LFTLKFIFTA
HHHHHHHHCC
>Mature Secondary Structure
MLEKLFQLKANGTNVRTEIIAGLTTFLTMAYVIFVNPAILADAGMDKGAVFVATCIAAAI
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHH
GCFIMGFVANFPIAQAPGMGLNAFFTYTVVLGMGHTWQVALAAVFMSGVLFILLSLCKIR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELIINSIPLSLRTGISAGIGLFLAFIALKNSGIVVDNPATLLSIGHINSFPAAMGALALF
HHHHHCCCHHHHHCHHHHHHHHHHHHHHCCCCEEEECCHHEEEECCCCCHHHHHHHHHHH
LTIALVHRGYKAAVMIAILAVTGLALLFGEVQYAGIMSMPPSLAPTFLQLDFSGAFDIGM
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCEEEEECCCCCHHHH
LSVVFAFLFVDLFDTAGTLVGVSQKAGIMDKDGNIPRLNRALLADSTATSVGALLGTSNT
HHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCH
TSYIESVAGVAAGGRTGLTAVVVGILFLLALFFAPLAGMVPAYATAGALFYVAILMMSGL
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VSIDWRDLTEAAPVVVVCLLMPLTFSIADGISLGFISYAAIKLLSGKGRDVHISVWVLAA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHH
LFTLKFIFTA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]