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The map label for this gene is dinB [H]

Identifier: 209694530

GI number: 209694530

Start: 1063619

End: 1064671

Strand: Reverse

Name: dinB [H]

Synonym: VSAL_I0965

Alternate gene names: 209694530

Gene position: 1064671-1063619 (Counterclockwise)

Preceding gene: 209694531

Following gene: 209694529

Centisome position: 32.02

GC content: 36.09

Gene sequence:

>1053_bases
TTGTCTCAAAAAATAATTCACATTGACCTTGATTGTTACTACGCAGCTGTTGAAGCGAGAGACAACCCAGAGTTACGGGG
AATCCCTATTGCCATTGGAGGCTCTCAACATCATCGTGGCGTGCTTTCAACATGTAATTATGAAGCACGGGAATTTGGCG
TTCGCTCTGCCATGTCTACCGCTAAAGCCCTACAGTTATGCCCGAATTTAACCGTTGTACCTGGTAACATGGATAAATAC
AAAACCGTTTCAAAACAAATTCATAAAATATTCTCAGAATATACTGACCTCATTGAACCACTTTCATTGGATGAAGCCTA
TCTCGATGTCACCGACTCTCCATTATTTCACGGTTCCGCTACTTTAATTGCAGAAGATATTAGGAAAACGATCTGGAACG
AGTTACAACTAACAGCAAGTGCGGGAGTAGCACCTTTAAAATTTATAGCTAAAGTTGCATCCGATGTAGATAAGCCTAAT
GGAATCTGTGTTGTTCCCCCAAACAAACTAGATAGTTTCATTGAACAGCTTGAACTAGGAAAAATATCCGGCGTTGGTAA
GGTAACTTTAGAAAAGCTACATAAGTTTGGTTTCTATAAAGGTCAAGATATTAGGGAGTGCGATCATCATACACTGCTAA
GCAACTTTGGAAAATTTGGTCAAGTTATATGGGAAAGATGTAATGGTATAGATAACCGTAAAATTGAAACAAATCGAACT
CGTAAATCTGTTGGTGTAGAAAGAACCTTCCAAACTGACATTTATTCTGAACAAGAATGCATTGAAGCTATTGAAGTTCT
TTATCCAAAACTAATTGAAAGACTACAAAAATCCTCAAGTAATAACAGCATTATAAAGCAAGGGTTAAAGTTAAAATTTC
AGGATTTCAAGCAAACTACTATCGAGCATAAAAAATCACAATTAGATAAAGATTACTTCTTAGAATTACTACGAGAAGGG
TTAAAAAGACAACAAAACCGAGGCATTAGATTAATAGGTATATCTATTGGTTTAAATACAGAAAAAGATAGTGGTCAAAT
TAACTTATTCTAG

Upstream 100 bases:

>100_bases
TTAGACTTAAAGAACTAATCTAAAACAACCCGTCATGAAACCTAATCTTAGTATAATGGTATAGACGATTATTGAATTGA
ATCCGTTAGGCTAAATTGTT

Downstream 100 bases:

>100_bases
AATAGATTAGCATTTAAATTAACTCGTTGTTGTCCCAAATTTTGTTACGTTACAAATTTCATTATTCAGATAATTAGCTA
GTTTTAAAATACAAAAAAAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSQKIIHIDLDCYYAAVEARDNPELRGIPIAIGGSQHHRGVLSTCNYEAREFGVRSAMSTAKALQLCPNLTVVPGNMDKY
KTVSKQIHKIFSEYTDLIEPLSLDEAYLDVTDSPLFHGSATLIAEDIRKTIWNELQLTASAGVAPLKFIAKVASDVDKPN
GICVVPPNKLDSFIEQLELGKISGVGKVTLEKLHKFGFYKGQDIRECDHHTLLSNFGKFGQVIWERCNGIDNRKIETNRT
RKSVGVERTFQTDIYSEQECIEAIEVLYPKLIERLQKSSSNNSIIKQGLKLKFQDFKQTTIEHKKSQLDKDYFLELLREG
LKRQQNRGIRLIGISIGLNTEKDSGQINLF

Sequences:

>Translated_350_residues
MSQKIIHIDLDCYYAAVEARDNPELRGIPIAIGGSQHHRGVLSTCNYEAREFGVRSAMSTAKALQLCPNLTVVPGNMDKY
KTVSKQIHKIFSEYTDLIEPLSLDEAYLDVTDSPLFHGSATLIAEDIRKTIWNELQLTASAGVAPLKFIAKVASDVDKPN
GICVVPPNKLDSFIEQLELGKISGVGKVTLEKLHKFGFYKGQDIRECDHHTLLSNFGKFGQVIWERCNGIDNRKIETNRT
RKSVGVERTFQTDIYSEQECIEAIEVLYPKLIERLQKSSSNNSIIKQGLKLKFQDFKQTTIEHKKSQLDKDYFLELLREG
LKRQQNRGIRLIGISIGLNTEKDSGQINLF
>Mature_349_residues
SQKIIHIDLDCYYAAVEARDNPELRGIPIAIGGSQHHRGVLSTCNYEAREFGVRSAMSTAKALQLCPNLTVVPGNMDKYK
TVSKQIHKIFSEYTDLIEPLSLDEAYLDVTDSPLFHGSATLIAEDIRKTIWNELQLTASAGVAPLKFIAKVASDVDKPNG
ICVVPPNKLDSFIEQLELGKISGVGKVTLEKLHKFGFYKGQDIRECDHHTLLSNFGKFGQVIWERCNGIDNRKIETNRTR
KSVGVERTFQTDIYSEQECIEAIEVLYPKLIERLQKSSSNNSIIKQGLKLKFQDFKQTTIEHKKSQLDKDYFLELLREGL
KRQQNRGIRLIGISIGLNTEKDSGQINLF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=297, Percent_Identity=27.6094276094276, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7706681, Length=298, Percent_Identity=27.5167785234899, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI7705344, Length=111, Percent_Identity=52.2522522522522, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI154350220, Length=313, Percent_Identity=29.3929712460064, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI5729982, Length=114, Percent_Identity=35.9649122807018, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786425, Length=337, Percent_Identity=56.973293768546, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI193205700, Length=314, Percent_Identity=32.8025477707006, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537959, Length=285, Percent_Identity=28.4210526315789, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI115534089, Length=126, Percent_Identity=37.3015873015873, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=205, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=325, Percent_Identity=27.0769230769231, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21355641, Length=343, Percent_Identity=26.530612244898, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24644984, Length=343, Percent_Identity=26.530612244898, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24668444, Length=447, Percent_Identity=23.9373601789709, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39517; Mature: 39386

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKIIHIDLDCYYAAVEARDNPELRGIPIAIGGSQHHRGVLSTCNYEAREFGVRSAMST
CCCCEEEEECCEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHH
AKALQLCPNLTVVPGNMDKYKTVSKQIHKIFSEYTDLIEPLSLDEAYLDVTDSPLFHGSA
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHH
TLIAEDIRKTIWNELQLTASAGVAPLKFIAKVASDVDKPNGICVVPPNKLDSFIEQLELG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHC
KISGVGKVTLEKLHKFGFYKGQDIRECDHHTLLSNFGKFGQVIWERCNGIDNRKIETNRT
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RKSVGVERTFQTDIYSEQECIEAIEVLYPKLIERLQKSSSNNSIIKQGLKLKFQDFKQTT
HHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHH
IEHKKSQLDKDYFLELLREGLKRQQNRGIRLIGISIGLNTEKDSGQINLF
HHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEECC
>Mature Secondary Structure 
SQKIIHIDLDCYYAAVEARDNPELRGIPIAIGGSQHHRGVLSTCNYEAREFGVRSAMST
CCCEEEEECCEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHH
AKALQLCPNLTVVPGNMDKYKTVSKQIHKIFSEYTDLIEPLSLDEAYLDVTDSPLFHGSA
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHH
TLIAEDIRKTIWNELQLTASAGVAPLKFIAKVASDVDKPNGICVVPPNKLDSFIEQLELG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHC
KISGVGKVTLEKLHKFGFYKGQDIRECDHHTLLSNFGKFGQVIWERCNGIDNRKIETNRT
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
RKSVGVERTFQTDIYSEQECIEAIEVLYPKLIERLQKSSSNNSIIKQGLKLKFQDFKQTT
HHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHH
IEHKKSQLDKDYFLELLREGLKRQQNRGIRLIGISIGLNTEKDSGQINLF
HHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA