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The map label for this gene is nqrA

Identifier: 209694516

GI number: 209694516

Start: 1046336

End: 1047676

Strand: Direct

Name: nqrA

Synonym: VSAL_I0949

Alternate gene names: 209694516

Gene position: 1046336-1047676 (Clockwise)

Preceding gene: 209694515

Following gene: 209694517

Centisome position: 31.47

GC content: 41.54

Gene sequence:

>1341_bases
ATGATTACAATAAAAAAGGGTTTGGATCTTCCTATAGCAGGAGTTCCAACTCAGGTGATTAATGATGGTAATTCCATCAC
TAAAGTCGCCTTGCTTGGCGAAGAGTATGTTGGTATGCGTCCTACGATGCATGCTCGCGTTGAAGATGTAGTTAAAAAAG
GTCAGATTCTTTTTGCTGATAAAAAGAATCCTGGTGTTATTTTTACATCTCCAGTAAGTGGTAAAGTTGTTGAAATTAAC
CGTGGTGCTAAACGTGTACTTCAATCTGTAGTAATTGCAGTTGAAGGCGAAGAGCAGGTTACTTTTAATAGCTATGCAGC
AAATCAGTTGGCTTCTCTTGATCGTGATGCGATCAAGCAACAGCTTATTGATTCTGGTGCATGGACTGCATTACGTACTC
GTCCGTTCAGCAAGGTTCCAGCGATCGATTCTGAAACAAAGGCTATCTTTGTAACTGCTATGGATACTAATCCTTTAGCA
GCTGATGCAGAAGTGATCATCAACCAACAAGAAGACGCTTTTGTTGCAGGCCTAGATTTATTATCTGTGTTAACAGGTGA
GAAGGTTTATGTATGTAAGAAAGGTGGGAGTTTACCTCGCTCTTCTCAAGGCAATGTTGAAGAACATGTATTTGATGGCC
CTCATCCAGCAGGGTTAGCGGGTACTCACATGCATTATTTGTATCCTGTGGATCTAAATAATGTGGCGTGGAGCATTGGC
TACCAAGACGTTATTGCTTTTGGTCAATTATTCTTAACGGGTGAAATCTACTCTGACAGAATCGTATCTTTAGCTGGACC
TGCCGTAAATAATCCTCGTTTAGTTCGTACTATTACTGGTGCTAGCTTACTTGAATTAACTGACAGCGAAGTAATGCCTG
GTGAAGTACGAATCATTTCTGGTTCTGTATTAAATGGTACTCAAGCGTCTGGCCCTCATGCCTACCTTGGTCCTTACCAT
CAGCAAGTATGTGTTCTTCGTGAAGGTCGTGAGAAAGAGTTTTTAGGCTGGGCTGTCCCTGGTAAAAACAAATTCTCTGT
TACTCGTTCATTCCTAAGCCATGTATTCTCAGGTCAATTGTTTAACATGACAACAACTACCAATGGTAGTGATCGTGCAA
TGGTGCCAATTGGTAGTTACGAACGTGTAATGCCTTTAGACATGGAACCTACCATGTTATTGCGTGACCTTTGTGCTGGT
GATGTTGACAGTGCTGCACGTTTAGGTGCATTAGAATTAGATGAAGATGATCTAGGTCTATGTACGTATGTGTGCCCTGG
TAAATATGAGTATGGTCCAATGCTTCGTGAGATTTTGGATACCATCGAGAAGGAAGGGTAA

Upstream 100 bases:

>100_bases
TTATTGTGTTGATAGTTTTAATTATTAACACTGAACATGAATTAGTAATGTCGTGTCTTATATAGAATCCTTTTTCCCAA
TTAAATTAGTGCAAGTGCGT

Downstream 100 bases:

>100_bases
TCAATGAGCCTGTTAAAGATTATTGAAAAAATTGAACCTCATTTTGAACCTGGCGGTAAATATGAGAAGTGGTTTGCGCT
TTATGAAGCGGCTGCAACTC

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFADKKNPGVIFTSPVSGKVVEIN
RGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQQLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLA
ADAEVIINQQEDAFVAGLDLLSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIG
YQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIISGSVLNGTQASGPHAYLGPYH
QQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQLFNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAG
DVDSAARLGALELDEDDLGLCTYVCPGKYEYGPMLREILDTIEKEG

Sequences:

>Translated_446_residues
MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFADKKNPGVIFTSPVSGKVVEIN
RGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQQLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLA
ADAEVIINQQEDAFVAGLDLLSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIG
YQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIISGSVLNGTQASGPHAYLGPYH
QQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQLFNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAG
DVDSAARLGALELDEDDLGLCTYVCPGKYEYGPMLREILDTIEKEG
>Mature_446_residues
MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFADKKNPGVIFTSPVSGKVVEIN
RGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQQLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLA
ADAEVIINQQEDAFVAGLDLLSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIG
YQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIISGSVLNGTQASGPHAYLGPYH
QQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQLFNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAG
DVDSAARLGALELDEDDLGLCTYVCPGKYEYGPMLREILDTIEKEG

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_ALISL (B6EIC3)

Other databases:

- EMBL:   FM178379
- RefSeq:   YP_002262444.1
- GeneID:   6988293
- GenomeReviews:   FM178379_GR
- KEGG:   vsa:VSAL_I0949
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 48316; Mature: 48316

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFAD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHCCCEEEEE
KKNPGVIFTSPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQ
CCCCCEEEECCCCCEEEEECCHHHHHHHHEEEEECCCCEEEECHHHHHHHHHCCHHHHHH
QLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAADAEVIINQQEDAFVAGLDL
HHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHH
LSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIG
HHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEECC
YQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIIS
HHHHHHHHHEEEEEEHHHCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEE
GSVLNGTQASGPHAYLGPYHQQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQL
CCEECCCCCCCCCCCCCCHHHHHHEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEE
FNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAGDVDSAARLGALELDEDDLGL
EEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHCCCCCHHHHCCEEEECCCCCCE
CTYVCPGKYEYGPMLREILDTIEKEG
EEEECCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFAD
CEEECCCCCCCCCCCCHHHHCCCCCEEEEEEECCHHCCCCCCHHHHHHHHHHCCCEEEEE
KKNPGVIFTSPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQ
CCCCCEEEECCCCCEEEEECCHHHHHHHHEEEEECCCCEEEECHHHHHHHHHCCHHHHHH
QLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAADAEVIINQQEDAFVAGLDL
HHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHH
LSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIG
HHHHCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEECC
YQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIIS
HHHHHHHHHEEEEEEHHHCCEEEECCCCCCCCEEEEEECCCEEEEECCCCCCCCEEEEEE
GSVLNGTQASGPHAYLGPYHQQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQL
CCEECCCCCCCCCCCCCCHHHHHHEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCEE
FNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAGDVDSAARLGALELDEDDLGL
EEEEECCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHCCCCCHHHHCCEEEECCCCCCE
CTYVCPGKYEYGPMLREILDTIEKEG
EEEECCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA